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| Registros recuperados : 15 | |
| Registros recuperados : 15 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Semiárido; Embrapa Uva e Vinho. |
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Data corrente: |
21/05/2014 |
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Data da última atualização: |
02/04/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
DENNY, C.; LAZARINI, J. G.; FRANCHIN, M.; MELO, P. S.; PEREIRA, G. E.; MASSARIOLI, A. P.; MORENO, I. A. M.; PASCHOAL, J. A. R.; ALENCAR, S. M.; ROSALEN, P. L. |
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Afiliação: |
Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; GIULIANO ELIAS PEREIRA, CNPUV; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo; Department of Agri-food Industry, Food and Nutrition, ‘Luiz de Queiroz’ College of Agriculture, University of São Paulo; Piracicaba Dental School, Department of Physiological Sciences, University of Campinas. |
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Título: |
Bioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Journal of Functional Foods, v. 8, p. 292-300, 2014. |
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Idioma: |
Inglês |
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Conteúdo: |
The aim of this study was to evaluate the anti-inflammatory activity of Petit Verdot Extract and hexane, chloroform and ethyl acetate fractions obtained from grape pomace, in addition to identifying active compounds. The PVE and EAF reduced significantly paw edema and neutrophil migration when compared with control groups. The PVE reduced levels of TNF-α and IL1-β in the peritoneal fluid, whereas the EAF did not reduce cytokines significantly. Two hydroxybenzoic acids, two proanthocyanidins, three flavan-3-ol monomers and three anthocyanins were identified in the PVE and EAF by LC-MS/MS. The stilbene transresveratrol was identified only in the EAF. The phenolic compounds were quantified using HPLC-DAD analysis, except for the stilbenes, which were not sensible for the detection by the method. Since PVE and EAF showed significantly anti-inflammatory effects and high concentration of phenolic compounds, we concluded that Petit Verdot pomace could be an interesting source of anti-inflammatory bioactives. |
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Palavras-Chave: |
Bagaço de uva; Citocinas; Petit Verdot; Subprodutos. |
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Thesagro: |
Antiinflamatorio; Bagaço; Composto fenolico; Uva; Vitis Vinifera. |
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Thesaurus NAL: |
Anti-inflammatory activity; Grape pomace; Grapes; Phenolic compounds. |
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Categoria do assunto: |
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F Plantas e Produtos de Origem Vegetal |
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URL: |
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/986684/1/Bioprospection.pdf
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/991125/1/Giuliano2014.pdf
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Marc: |
LEADER 02055naa a2200385 a 4500
001 1986684
005 2019-04-02
008 2014 bl uuuu u00u1 u #d
100 1 $aDENNY, C.
245 $aBioprospection of Petit Verdot grape pomace as a source of anti-inflammatory compounds.
260 $c2014
520 $aThe aim of this study was to evaluate the anti-inflammatory activity of Petit Verdot Extract and hexane, chloroform and ethyl acetate fractions obtained from grape pomace, in addition to identifying active compounds. The PVE and EAF reduced significantly paw edema and neutrophil migration when compared with control groups. The PVE reduced levels of TNF-α and IL1-β in the peritoneal fluid, whereas the EAF did not reduce cytokines significantly. Two hydroxybenzoic acids, two proanthocyanidins, three flavan-3-ol monomers and three anthocyanins were identified in the PVE and EAF by LC-MS/MS. The stilbene transresveratrol was identified only in the EAF. The phenolic compounds were quantified using HPLC-DAD analysis, except for the stilbenes, which were not sensible for the detection by the method. Since PVE and EAF showed significantly anti-inflammatory effects and high concentration of phenolic compounds, we concluded that Petit Verdot pomace could be an interesting source of anti-inflammatory bioactives.
650 $aAnti-inflammatory activity
650 $aGrape pomace
650 $aGrapes
650 $aPhenolic compounds
650 $aAntiinflamatorio
650 $aBagaço
650 $aComposto fenolico
650 $aUva
650 $aVitis Vinifera
653 $aBagaço de uva
653 $aCitocinas
653 $aPetit Verdot
653 $aSubprodutos
700 1 $aLAZARINI, J. G.
700 1 $aFRANCHIN, M.
700 1 $aMELO, P. S.
700 1 $aPEREIRA, G. E.
700 1 $aMASSARIOLI, A. P.
700 1 $aMORENO, I. A. M.
700 1 $aPASCHOAL, J. A. R.
700 1 $aALENCAR, S. M.
700 1 $aROSALEN, P. L.
773 $tJournal of Functional Foods$gv. 8, p. 292-300, 2014.
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Registro original: |
Embrapa Uva e Vinho (CNPUV) |
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