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| 1. |  | SOARES, J. K. B.; MELO, A. P. R. de; MEDEIROS, M. C.; QUEIROGA, R. C. R. E.; BOMFIM, M. A. D.; SANTIAGO, E. C. A.; GUEDES, R. C. A. Anxiety behavior is reduced, and physical growth is improved in theprogeny of rat dams that consumed lipids from goat milk: An elevatedplus maze analysis. Neuroscience Letters, v. 552, p. 25-29, Sept., 2013.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 2. | | SOARES, J. K. B.; ROCHA-DE-MELO, A. P.; MEDEIROS, M. C.; QUEIROGA, R. C. R. E.; BOMFIM, M. A. D.; SOUZA, A. F. O. de; NASCIMENTO, A. L. V.; GUEDES, R. C. A. Conjugated linoleic acid in the maternal diet differentially enhances growth and cortical spreading depression in the rat progeny. Biochimica et Biophysica Acta (BBA) - General Subjects, v. 1820, n. 10, p. 1490-1495, Oct., 2012.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| Registros recuperados : 2 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
19/11/2012 |
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Data da última atualização: |
24/04/2015 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SOARES, J. K. B.; ROCHA-DE-MELO, A. P.; MEDEIROS, M. C.; QUEIROGA, R. C. R. E.; BOMFIM, M. A. D.; SOUZA, A. F. O. de; NASCIMENTO, A. L. V.; GUEDES, R. C. A. |
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Afiliação: |
Juliana K. B. Soares, Universidade Federal de Pernambuco (UFPE), Recife, PE; Ana P. Rocha-de-Melo, Universidade Federal de Pernambuco (UFPE), Recife, PE; Maria C. Medeiros, Universidade Federal de Pernambuco (UFPE), Recife, PE; Rita C. R. E. Queiroga, Universidade Federal da Paraíba (UFPB) - Campina Grande, PB; MARCO AURELIO DELMONDES BOMFIM, CNPC; Amanda F. O. de Souza, Universidade Federal de Pernambuco (UFPE), Recife, PE; Ana L. V. Nascimento, Universidade Federal de Pernambuco (UFPE), Recife, PE; Rubem C. A. Guedes, Universidade Federal de Pernambuco (UFPE), Recife, PE. |
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Título: |
Conjugated linoleic acid in the maternal diet differentially enhances growth and cortical spreading depression in the rat progeny. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Biochimica et Biophysica Acta (BBA) - General Subjects, v. 1820, n. 10, p. 1490-1495, Oct., 2012. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract - Background: Conjugated linoleic acids (CLA) are fatty acids that are found in the lipids from goat milk, and appear to protect neurons from excitotoxicity. Methods: We investigated in developing rats the effects of a maternal CLA-rich diet (containing 7% lipids from goat milk) on body development and cerebral electrical activity of the progeny from dams receiving the CLA diet during gestation (G), lactation (L) or both periods (G + L). Results: Compared to a control group (C) receiving a diet with 7% soybean oil, body weight increased at 14, 21 and 28 days, but not at 35-45 days, in L and G + L groups (P < 0.05). No intergroup difference was found on body and brain weights, body length, abdominal and thoracic circumferences, body mass index and abdominal to thoracic circumference ratio at 35?45 days. In contrast, at this later age the CSD velocities of propagation were significantly higher (P < 0.05) in L as compared with the C and G group, and in the L + G, as compared with the C, G and L groups, suggesting a long-lasting brain effect. Conclusion: These data indicate that a maternal CLA-rich diet can differentially influence body weight increment (short-term effect), and CSD propagation (long-term effect) in the progeny, and the lactation is the most critical period for such diet actions. General significance. The facilitating effect of the lipids from goat milk on an excitability-related phenomenon in the brain (CSD) can be of clinical relevance, since CSD has been associated to neurological disturbances like migraine and epilepsy. MenosAbstract - Background: Conjugated linoleic acids (CLA) are fatty acids that are found in the lipids from goat milk, and appear to protect neurons from excitotoxicity. Methods: We investigated in developing rats the effects of a maternal CLA-rich diet (containing 7% lipids from goat milk) on body development and cerebral electrical activity of the progeny from dams receiving the CLA diet during gestation (G), lactation (L) or both periods (G + L). Results: Compared to a control group (C) receiving a diet with 7% soybean oil, body weight increased at 14, 21 and 28 days, but not at 35-45 days, in L and G + L groups (P < 0.05). No intergroup difference was found on body and brain weights, body length, abdominal and thoracic circumferences, body mass index and abdominal to thoracic circumference ratio at 35?45 days. In contrast, at this later age the CSD velocities of propagation were significantly higher (P < 0.05) in L as compared with the C and G group, and in the L + G, as compared with the C, G and L groups, suggesting a long-lasting brain effect. Conclusion: These data indicate that a maternal CLA-rich diet can differentially influence body weight increment (short-term effect), and CSD propagation (long-term effect) in the progeny, and the lactation is the most critical period for such diet actions. General significance. The facilitating effect of the lipids from goat milk on an excitability-related phenomenon in the brain (CSD) can be of clinical relevance, since CSD has b... Mostrar Tudo |
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Palavras-Chave: |
Brain development; Brain electrophysiology; Cortical spreading depression; Drug effects; Physical parameter. |
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Thesagro: |
Ácido linoleico; Caprino; Leite de cabra. |
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Thesaurus NAL: |
Goat milk; Linoleic acid; Polyunsaturated fatty acids; Rats. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
http://ainfo.cnptia.embrapa.br/digital/bitstream/item/70369/1/API-Conjugated-linoleic.pdf
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Marc: |
LEADER 02685naa a2200349 a 4500
001 1939969
005 2015-04-24
008 2012 bl uuuu u00u1 u #d
100 1 $aSOARES, J. K. B.
245 $aConjugated linoleic acid in the maternal diet differentially enhances growth and cortical spreading depression in the rat progeny.$h[electronic resource]
260 $c2012
520 $aAbstract - Background: Conjugated linoleic acids (CLA) are fatty acids that are found in the lipids from goat milk, and appear to protect neurons from excitotoxicity. Methods: We investigated in developing rats the effects of a maternal CLA-rich diet (containing 7% lipids from goat milk) on body development and cerebral electrical activity of the progeny from dams receiving the CLA diet during gestation (G), lactation (L) or both periods (G + L). Results: Compared to a control group (C) receiving a diet with 7% soybean oil, body weight increased at 14, 21 and 28 days, but not at 35-45 days, in L and G + L groups (P < 0.05). No intergroup difference was found on body and brain weights, body length, abdominal and thoracic circumferences, body mass index and abdominal to thoracic circumference ratio at 35?45 days. In contrast, at this later age the CSD velocities of propagation were significantly higher (P < 0.05) in L as compared with the C and G group, and in the L + G, as compared with the C, G and L groups, suggesting a long-lasting brain effect. Conclusion: These data indicate that a maternal CLA-rich diet can differentially influence body weight increment (short-term effect), and CSD propagation (long-term effect) in the progeny, and the lactation is the most critical period for such diet actions. General significance. The facilitating effect of the lipids from goat milk on an excitability-related phenomenon in the brain (CSD) can be of clinical relevance, since CSD has been associated to neurological disturbances like migraine and epilepsy.
650 $aGoat milk
650 $aLinoleic acid
650 $aPolyunsaturated fatty acids
650 $aRats
650 $aÁcido linoleico
650 $aCaprino
650 $aLeite de cabra
653 $aBrain development
653 $aBrain electrophysiology
653 $aCortical spreading depression
653 $aDrug effects
653 $aPhysical parameter
700 1 $aROCHA-DE-MELO, A. P.
700 1 $aMEDEIROS, M. C.
700 1 $aQUEIROGA, R. C. R. E.
700 1 $aBOMFIM, M. A. D.
700 1 $aSOUZA, A. F. O. de
700 1 $aNASCIMENTO, A. L. V.
700 1 $aGUEDES, R. C. A.
773 $tBiochimica et Biophysica Acta (BBA) - General Subjects$gv. 1820, n. 10, p. 1490-1495, Oct., 2012.
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Embrapa Caprinos e Ovinos (CNPC) |
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