| |
|
|
| Registros recuperados : 34 | |
| 4. |  | MOREIRA, C. S.; PIO, R. M. Melhoramento de citros 2.ed Campinas, SP: Fundacao Cargill, 1991 v.1 p.116-152 In: RODRIGUEZ, O.; VIEGAS, F.; POMPEU JUNIOR, J.; AMARO, A. A. Citricultura brasileira. Campinas, SP: Fundacao Cargill, 1980.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
|   |
| 6. | | PIO, R. M.; POMPEU JUNIOR, J.; BOAVENTURA, Y. M. S. Caracterizacao das laranjas doces `Homossassa', `Mangaratiba' e `Itaborai' Campinas: Sociedade Brasileira de Fruticultura, 1988. v.1 p.237-242 In: CONGRESSO BRASILEIRO DE FRUTICULTURA, 9., Campinas, 1987. Anais...Campinas, Sociedade Brasileira de Fruticultura, 1988.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
| |
| 7. | | PIO, R. M.; POMPEU JUNIOR, J.; BOAVENTURA, Y. M. S. Caracterizacao das laranjas doces seleta, sanguinea, tomango e tarocco Revista Brasileira de Fruticultura, v. 13, n.1, p.201-209, Cruz das Almas, 1991| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
| |
| 16. | | FIGUEIREDO, DE J. O.; JUNIOR, J. P.; PIO, R. M.; MULLER, G. W.; SOBRINHO, J. T. Levantamento da ocorrencia de caneluras da tristeza dos citrus em variedade de laranja doce. Revista Brasileira de Fruticultura, Cruz das Almas, v.13, n.4, p.49-51, 1991.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
| |
| 17. | | FIGUEIREDO, J. O. de; PIO, R. M.; TEOFILO SOBRINHO, J.; LARANJEIRA, F. F. SALIBE, A. A. Comportamento de quinze porta-enxertos para o tangot "Murcott' na Regiao de Porto Feliz, SP1 Revista Brasileira de Fruticultura, Jaboticabal-SP, v.23, n.1, p.147-151, 2001| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
| |
| 18. | | PIO, R. M.; MINAMI, K.; FIGUEIREDO, J. O. de; POMPEU JUNIOR, J. Caracterizacao e avaliacao de duas novas variedades hibridas de tangerina 'Clementina' Laranja: Revista Tecnico-Cientifica de Citricultura, v.21, n.1, p.149-159, Cordeiropolis, SP, 2000| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
| |
| Registros recuperados : 34 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
25/09/2023 |
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Data da última atualização: |
25/09/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GRIZZO, A.; SANTOS, D. M. dos; COSTA, V. P. V. da; LOPES, R. G.; INADA, N. M.; CORREA, D. S.; CAMPANA-FILHO, S. P. |
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Afiliação: |
Sao Carlos Institute of Chemistry/University of Sao Paulo; Nanotechnology National Laboratory for Agriculture (LNNA); Center for Exact Sciences and Technology, Federal University of Sao Carlos (UFSCar); Sao Carlos Institute of Physics/University of Sao Paulo; Sao Carlos Institute of Physics/University of Sao Paulo; DANIEL SOUZA CORREA, CNPDIA; CAMPANA-FILHO, S. P., Sao Carlos Institute of Chemistry/University of Sao Paulo. |
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Título: |
Multifunctional bilayer membranes composed of poly(lactic acid), beta-chitin whiskers and silver nanoparticles for wound dressing applications. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
International Journal of Biological Macromolecules, v. 251, 126314, 2023. |
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ISSN: |
0141-8130 |
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DOI: |
https://doi.org/10.1016/j.ijbiomac.2023.126314 |
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Idioma: |
Inglês |
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Conteúdo: |
Nanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal human dermal fibroblast (HDFn) cell line. Moreover, bilayer membranes exhibited a high surface area and porosity (> 80%), remarkable stability in aqueous media, and favorable mechanical properties, making them promising candidates for application as multifunctional wound dressings. MenosNanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal hu... Mostrar Tudo |
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Palavras-Chave: |
Beta-chitin whiskers; Biocompatible material; Electrospun nanofibers; Natural polymer; Solution blow spinning; Wound dressing. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02746naa a2200289 a 4500
001 2156857
005 2023-09-25
008 2023 bl uuuu u00u1 u #d
022 $a0141-8130
024 7 $ahttps://doi.org/10.1016/j.ijbiomac.2023.126314$2DOI
100 1 $aGRIZZO, A.
245 $aMultifunctional bilayer membranes composed of poly(lactic acid), beta-chitin whiskers and silver nanoparticles for wound dressing applications.$h[electronic resource]
260 $c2023
520 $aNanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal human dermal fibroblast (HDFn) cell line. Moreover, bilayer membranes exhibited a high surface area and porosity (> 80%), remarkable stability in aqueous media, and favorable mechanical properties, making them promising candidates for application as multifunctional wound dressings.
653 $aBeta-chitin whiskers
653 $aBiocompatible material
653 $aElectrospun nanofibers
653 $aNatural polymer
653 $aSolution blow spinning
653 $aWound dressing
700 1 $aSANTOS, D. M. dos
700 1 $aCOSTA, V. P. V. da
700 1 $aLOPES, R. G.
700 1 $aINADA, N. M.
700 1 $aCORREA, D. S.
700 1 $aCAMPANA-FILHO, S. P.
773 $tInternational Journal of Biological Macromolecules$gv. 251, 126314, 2023.
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