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| Registros recuperados : 19 | |
| 5. |  | CAMPOS, A. R. N.; SILVA, F. L. H. da; GOMES, J. P.; OLIVEIRA, L. S. C.; OLIVEIRA, M. M. Isotermas de adsorção e calor isostérico da palma forrageira enriquecida proteicamente. Revista Brasileira de Engenharia Agrícola e Ambiental, v. 13, n. 6, p. 734-740, nov./dez., 2009. 1 CD-ROM| Biblioteca(s): Embrapa Algodão. |
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| 9. | | SANTOS, S. F. de M.; SOUZA, R. L. A. de; ALCÂNTARA, S. R.; PINTO, G. A. S.; SILVA, F. L. H. da; MACEDO, G. R. de. Aplicação da metodologia de superfície de resposta no estudo da produção de pectinase por fermentação em estado sólido do pedúnculo de caju. Revista Brasileira de Produtos Agroindustriais, v. 10, n. 2, p. 101-109, 2008.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 12. | | ALMEIDA, M. M. de; SILVA, F. L. H. da; OLIVEIRA, L. de S. C.; FREIRE, R. M. M.; CAIÇARA, J. J. Enriquecimento protéico do mandacaru (Cereus jamacaru p.dc.) em tambor rotativo. In: CONGRESSO BRASILEIRO DE ENGENHARIA QUÍMICA, 17.; CONGRESSO BRASILEIRO DE TERMODINâMICA APLICADA, 4., 2008, Recife. Engenharia Química energia e novos desafios: [anais]. Recife, 2008. 8 p.| Biblioteca(s): Embrapa Algodão. |
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| 14. | | SANTOS, R. T. dos S. e; TORRES, L. H. P. S.; BIASOTO, A. C. T.; FREITAS, S. T. de; MELO, N. F. de; SILVA, F. L. H. da. Optimization of pectinolytic hydrolysis in Caatinga passion fruit wine must with commercial pectinase, according to the central composite rotatable design approach. Research, Society and Development, v. 11, n. 5, e14511528088, 2022.| Biblioteca(s): Embrapa Semiárido. |
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| 15. | | ALMEIDA, M. M. de; SILVA, F. L. H. da; OLIVEIRA, L. de S. C.; MOTA, J. C.; FREIRE, R. M. M.; AMORIM, B. C. Produção e caracterização do fermentado acético do fruto do mandacaru. In: SIMPÓSIO NACIONAL DE BIOPROCESSOS, 17., 2009, Natal. Anais... Natal: Universidade Federal do Rio Grande do Norte, 2009. 3 p.| Biblioteca(s): Embrapa Algodão. |
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| 16. | | SOUSA, W. J. B. de; ALMEIDA, K. V. de; RIBEIRO FILHO, N. M.; SILVA, F. L. H. da; FIRMINO, P. de T.; ROCHA, A. S. Produção de aguardente de laranja. In: CONGRESSO NORTE-NORDESTE DE QUÍMICA, 3.; ENCONTRO NORTE-NORDESTE DE ENSINO DE QUÍMICA, 1., 2009, São Luís.São Luís, 2009. 1 CD-ROM| Biblioteca(s): Embrapa Algodão. |
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| 17. | | SANTOS, R. T. dos S. e; RYBKA, A. C. P.; CASTRO, C. D. P. da C.; AIDAR, S. de T.; BIASOTO, A. C. T.; SILVA, F. L. H. da. Desenvolvimento de fermentado alcoólico de maracujá da Caatinga a partir de frutos colhidos em diferentes estádios de maturação. In: ENCONTRO NACIONAL DA AGROINDÚSTRIA, 5., Bananeiras, PB. Anais eletrônico... Campinas: GALOA, 2019.| Biblioteca(s): Embrapa Semiárido. |
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| 18. | | CHEN, L. S.; HECK, J. X.; JESUS, K. R. E. de; ORTEGA, C. E.; RIZZATO, M. L.; SILVA, D.; SILVA, F. L. H. da; DEL BIANCHI, V. L.; KRIEGER, N.; MORAES, R. O.; SOARES, C. M. Produção de enzimas proteolíticas neutras por fermentação fúngica em meio semi-sólido. In: SIMPÓSIO NACIONAL DE FERMENTAÇÕES, 14., Florianópolis, 2003. Anais... Florianópolis: Universidade Federal de Santa Catarina, Centro Tecnológico, Depto. de Eng. Química e Eng. Alimentos, 2003.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 19. | | MORAIS, S. DE M.; GALVÃO, M. DE S.; CARVALHO, L. M. DE; OLEGARIO, O. S.; PEREIRA, G. E.; ANDRADE LIMA, L. L. DE; SILVA, F. L. H. DA; MADRUGA, M. S. Potential typicality marker of volatile composition of commercial sparkling wines from the caatinga biome. Food Analytical Methods, s12161, July 2022.| Biblioteca(s): Embrapa Uva e Vinho. |
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| Registros recuperados : 19 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
25/09/2023 |
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Data da última atualização: |
25/09/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GRIZZO, A.; SANTOS, D. M. dos; COSTA, V. P. V. da; LOPES, R. G.; INADA, N. M.; CORREA, D. S.; CAMPANA-FILHO, S. P. |
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Afiliação: |
Sao Carlos Institute of Chemistry/University of Sao Paulo; Nanotechnology National Laboratory for Agriculture (LNNA); Center for Exact Sciences and Technology, Federal University of Sao Carlos (UFSCar); Sao Carlos Institute of Physics/University of Sao Paulo; Sao Carlos Institute of Physics/University of Sao Paulo; DANIEL SOUZA CORREA, CNPDIA; CAMPANA-FILHO, S. P., Sao Carlos Institute of Chemistry/University of Sao Paulo. |
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Título: |
Multifunctional bilayer membranes composed of poly(lactic acid), beta-chitin whiskers and silver nanoparticles for wound dressing applications. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
International Journal of Biological Macromolecules, v. 251, 126314, 2023. |
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ISSN: |
0141-8130 |
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DOI: |
https://doi.org/10.1016/j.ijbiomac.2023.126314 |
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Idioma: |
Inglês |
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Conteúdo: |
Nanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal human dermal fibroblast (HDFn) cell line. Moreover, bilayer membranes exhibited a high surface area and porosity (> 80%), remarkable stability in aqueous media, and favorable mechanical properties, making them promising candidates for application as multifunctional wound dressings. MenosNanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal hu... Mostrar Tudo |
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Palavras-Chave: |
Beta-chitin whiskers; Biocompatible material; Electrospun nanofibers; Natural polymer; Solution blow spinning; Wound dressing. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02746naa a2200289 a 4500
001 2156857
005 2023-09-25
008 2023 bl uuuu u00u1 u #d
022 $a0141-8130
024 7 $ahttps://doi.org/10.1016/j.ijbiomac.2023.126314$2DOI
100 1 $aGRIZZO, A.
245 $aMultifunctional bilayer membranes composed of poly(lactic acid), beta-chitin whiskers and silver nanoparticles for wound dressing applications.$h[electronic resource]
260 $c2023
520 $aNanomaterial-based wound dressings have been extensively studied for the treatment of both minor and lifethreatening tissue injuries. These wound dressings must possess several crucial characteristics, such as tissue compatibility, non-toxicity, appropriate biodegradability to facilitate wound healing, effective antibacterial activity to prevent infection, and adequate physical and mechanical strength to withstand repetitive dynamic forces that could potentially disrupt the healing process. Nevertheless, the development of nanostructured wound dressings that incorporate various functional micro- and nanomaterials in distinct architectures, each serving specific purposes, presents significant challenges. In this study, we successfully developed a novel multifunctional wound dressing based on poly(lactic acid) (PLA) fibrous membranes produced by solution-blow spinning (SBS) and electrospinning. The PLA-based membranes underwent surface modifications aimed at tailoring their properties for utilization as effective wound dressing platforms. Initially, beta-chitin whiskers were deposited onto the membrane surface through filtration, imparting hydrophilic character. Afterward, silver nanoparticles (AgNPs) were incorporated onto the beta-chitin layer using a spray deposition method, resulting in platforms with antimicrobial properties against both Staphylococcus aureus and Escherichia coli. Cytotoxicity studies demonstrated the biocompatibility of the membranes with the neonatal human dermal fibroblast (HDFn) cell line. Moreover, bilayer membranes exhibited a high surface area and porosity (> 80%), remarkable stability in aqueous media, and favorable mechanical properties, making them promising candidates for application as multifunctional wound dressings.
653 $aBeta-chitin whiskers
653 $aBiocompatible material
653 $aElectrospun nanofibers
653 $aNatural polymer
653 $aSolution blow spinning
653 $aWound dressing
700 1 $aSANTOS, D. M. dos
700 1 $aCOSTA, V. P. V. da
700 1 $aLOPES, R. G.
700 1 $aINADA, N. M.
700 1 $aCORREA, D. S.
700 1 $aCAMPANA-FILHO, S. P.
773 $tInternational Journal of Biological Macromolecules$gv. 251, 126314, 2023.
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