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2. | | MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; SANTOS, R. C. dos; RAMOS, J. P. C.; LIMA, L. M. de L.; ALENCAR, S. M. de. Optimizing procedures for antioxidant phenolics extraction from skin and kernel of peanuts with contrasting levels of drought tolerance. Foods, v. 11, n. 3, 449, p. 2-14, 2022. Biblioteca(s): Embrapa Algodão. |
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3. | | MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; AMARAL, J. E. P. G. do; SANTOS, R. C. dos; LIMA, L. M. de; ALENCAR, S. M. de. Simulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut. Food Chemistry, v. 400, 134036, p. 1-8, 2023. Biblioteca(s): Embrapa Algodão. |
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Registros recuperados : 3 | |
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Registro Completo
Biblioteca(s): |
Embrapa Algodão. |
Data corrente: |
28/03/2023 |
Data da última atualização: |
28/03/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; AMARAL, J. E. P. G. do; SANTOS, R. C. dos; LIMA, L. M. de; ALENCAR, S. M. de. |
Afiliação: |
ADNA PRADO MASSARIOLI, ESALQ; ALAN GIOVANINI DE OLIVEIRA SARTORI, ESALQ; FERNANDA FRANCETTO JULIANO, ESALQ; JOSÉ EDUARDO PEDROSO GOMES DO AMARAL, ESALQ; ROSEANE CAVALCANTI DOS SANTOS, CNPA; LIZIANE MARIA DE LIMA, CNPA; SEVERINO MATIAS DE ALENCAR, ESALQ. |
Título: |
Simulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
Food Chemistry, v. 400, 134036, p. 1-8, 2023. |
ISSN: |
2590-1575 |
Idioma: |
Inglês |
Conteúdo: |
Data concerning physiological recovery of whole peanut major phenolics throughout the gastrointestinal tract are scarce. In our study, the bioaccessibility and intestinal permeability of peanuts major phenolics were predicted by simulated digestion followed by Caco-2 cells monolayer model. Phenolics identification and quantification were performed by HPLC-ESI-QTOF-MS and HPLC-PDA, respectively. As results, p-coumaroyl conjugates with tartaric, sinapic and ferulic acids, and p-coumaric acid were the major phenolics found in the non-digested extract and in the digested and transported fractions. The in vitro bioaccessibility and Caco-2 cell transport of pcoumaric acid was 370% and 127%, respectively, while it was much lower for p-coumaroyl derivatives (7-100% and 14-31%, respectively). Nonetheless, the peroxyl scavenging activity remained unaltered, likely, at least artly, due to synergies between some phenolics, which concentration proportions changed throughout the experiment. Hence, there is indication that whole peanut is a source of bioavailable antioxidant phenolics. |
Thesagro: |
Amendoim; Nutrição Humana; Óleo Vegetal; Proteína Vegetal. |
Thesaurus NAL: |
Arid zones; Peanuts; Phenolic compounds. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1152824/1/SIMULATED-GASTROINTESTINAL-DIGESTION.pdf
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Marc: |
LEADER 01992naa a2200289 a 4500 001 2152824 005 2023-03-28 008 2023 bl uuuu u00u1 u #d 022 $a2590-1575 100 1 $aMASSARIOLI, A. P. 245 $aSimulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut.$h[electronic resource] 260 $c2023 520 $aData concerning physiological recovery of whole peanut major phenolics throughout the gastrointestinal tract are scarce. In our study, the bioaccessibility and intestinal permeability of peanuts major phenolics were predicted by simulated digestion followed by Caco-2 cells monolayer model. Phenolics identification and quantification were performed by HPLC-ESI-QTOF-MS and HPLC-PDA, respectively. As results, p-coumaroyl conjugates with tartaric, sinapic and ferulic acids, and p-coumaric acid were the major phenolics found in the non-digested extract and in the digested and transported fractions. The in vitro bioaccessibility and Caco-2 cell transport of pcoumaric acid was 370% and 127%, respectively, while it was much lower for p-coumaroyl derivatives (7-100% and 14-31%, respectively). Nonetheless, the peroxyl scavenging activity remained unaltered, likely, at least artly, due to synergies between some phenolics, which concentration proportions changed throughout the experiment. Hence, there is indication that whole peanut is a source of bioavailable antioxidant phenolics. 650 $aArid zones 650 $aPeanuts 650 $aPhenolic compounds 650 $aAmendoim 650 $aNutrição Humana 650 $aÓleo Vegetal 650 $aProteína Vegetal 700 1 $aSARTORI, A. G. de O. 700 1 $aJULIANO, F. F. 700 1 $aAMARAL, J. E. P. G. do 700 1 $aSANTOS, R. C. dos 700 1 $aLIMA, L. M. de 700 1 $aALENCAR, S. M. de 773 $tFood Chemistry$gv. 400, 134036, p. 1-8, 2023.
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Embrapa Algodão (CNPA) |
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