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Registro Completo |
Biblioteca(s): |
Embrapa Unidades Centrais. |
Data corrente: |
15/08/2016 |
Data da última atualização: |
15/08/2016 |
Autoria: |
ARGOLO NETO, N. M.; DEL CARLO, R. J.; MONTEIRO, B. S.; NARDI, N. B.; CHAGASTELLES, P. C.; BRITO, A. F. S.; REIS, A. M. S.; SILVA, L. M. C. |
Afiliação: |
NAPOLEÃO C. CHAGASTELLES, UFPI; RICARDO J. DEL CARLO, UFV; BETÂNEA S. MONTEIRO, UFV; NACE B. NARDI, ULBRA; PEDRO C. CHAGASTELLES, UFRGS; ANA FLORA S. BRITO, UFV; AMANDA M. S. REIS, UFV; LAÍS M. C. SILVA, UFPI. |
Título: |
Role of the autologous mesenchymal stem cells compared with platelet rich plasma on cicatrization of cutaneous wounds in diabetic mice. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Brasília, DF, v.36, n. 7, p. 617-624, jul. 2016. |
Idioma: |
Inglês |
Conteúdo: |
Chronic cutaneous lesions affect 15% of diabetic human patients and represent a risk 15 to 46 times larger of limb amputations compared to people with normal glycemia. It is assumed that half of these amputations could be prevented by early treatment of wounds, for example, with proper cell therapy. Objectives: In this study, the action of the autologous transplant of mesenchymal stem-cells (MSC) was evaluated compared to the treatment with autologous platelet rich plasma (PRP) in the cicatrization of cutaneous lesions induced in diabetic mice. These animals were previously treated with streptozootocin to induce diabetes mellitus and round wounds of 1.5cm in diameter were created in the posterior region. Diameters of the wounds and healing time were evaluated during 30 days and the results were submitted to variance analysis and Tukey?s test average. It was noticed that the animals treated with MSC presented a more accelerated cicatrization of the cutaneous lesion than the animals treated with PRP. However, the treatment with PRP presented better results than just the daily asepsis of the lesions with saline or covering them with semi-permeable bandage. Besides, the use of semi-permeable bandage kept the cutaneous lesions of diabetic mice did not interfere negatively with cicatrization, proved to be harmless to use, but kept the cutaneous lesions more hydrated than the ones exposed to the environment. |
Palavras-Chave: |
Célula-troncos mesenquimais; Cicatrização da lesão; Cicatrization; Mesenchymal stem cells. |
Thesagro: |
Lesão cutânea. |
Thesaurus Nal: |
diabetes mellitus; Skin lesions; Tissue repair. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/146380/1/Role-of-the-autologous.pdf
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Marc: |
LEADER 02376naa a2200301 a 4500 001 2050889 005 2016-08-15 008 2016 bl uuuu u00u1 u #d 100 1 $aARGOLO NETO, N. M. 245 $aRole of the autologous mesenchymal stem cells compared with platelet rich plasma on cicatrization of cutaneous wounds in diabetic mice. 260 $c2016 520 $aChronic cutaneous lesions affect 15% of diabetic human patients and represent a risk 15 to 46 times larger of limb amputations compared to people with normal glycemia. It is assumed that half of these amputations could be prevented by early treatment of wounds, for example, with proper cell therapy. Objectives: In this study, the action of the autologous transplant of mesenchymal stem-cells (MSC) was evaluated compared to the treatment with autologous platelet rich plasma (PRP) in the cicatrization of cutaneous lesions induced in diabetic mice. These animals were previously treated with streptozootocin to induce diabetes mellitus and round wounds of 1.5cm in diameter were created in the posterior region. Diameters of the wounds and healing time were evaluated during 30 days and the results were submitted to variance analysis and Tukey?s test average. It was noticed that the animals treated with MSC presented a more accelerated cicatrization of the cutaneous lesion than the animals treated with PRP. However, the treatment with PRP presented better results than just the daily asepsis of the lesions with saline or covering them with semi-permeable bandage. Besides, the use of semi-permeable bandage kept the cutaneous lesions of diabetic mice did not interfere negatively with cicatrization, proved to be harmless to use, but kept the cutaneous lesions more hydrated than the ones exposed to the environment. 650 $adiabetes mellitus 650 $aSkin lesions 650 $aTissue repair 650 $aLesão cutânea 653 $aCélula-troncos mesenquimais 653 $aCicatrização da lesão 653 $aCicatrization 653 $aMesenchymal stem cells 700 1 $aDEL CARLO, R. J. 700 1 $aMONTEIRO, B. S. 700 1 $aNARDI, N. B. 700 1 $aCHAGASTELLES, P. C. 700 1 $aBRITO, A. F. S. 700 1 $aREIS, A. M. S. 700 1 $aSILVA, L. M. C. 773 $tPesquisa Veterinária Brasileira, Brasília, DF$gv.36, n. 7, p. 617-624, jul. 2016.
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Embrapa Unidades Centrais (AI-SEDE) |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
13/12/2021 |
Data da última atualização: |
13/12/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
LOPES, M. A.; DEMEU, F. A.; REIS, E. M. B.; LIMA, A. L. R.; CARVALHO, F. DE M.; PALHARES, J. C. P.; COSTA, G. M. DA; PINHEIRO, M. V. G.; DEMEU, A. A. |
Afiliação: |
MARCOS AURÉLIO LOPES, UFLA; FABIANA ALVES DEMEU, Instituto Federal de Rondônia, IFRO; EDUARDO MITKE BRANDÃO REIS, Universidade Federal do Acre, UFAC; ANDRÉ LUIS RIBEIRO LIMA, UFLA; FRANCISVAL DE MELO CARVALHO, UFLA; JULIO CESAR PASCALE PALHARES, CPPSE; GERALDO MÁRCIO DA COSTA, UFLA; MARCELO VINÍCIUS GONTIJO PINHEIRO, Médico Veterinário, Autônomo, Ilícinea, MG; ANDRÉIA ALVES DEMEU, Zootecnista, Autônoma, Porto Velho, RO. |
Título: |
Economic viability of implementing an infrastructure for recycling bedding sand from a free-stall facility for dairy cows. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Semina, v.42, n.1, p.361-374, jan./fev. 2021. |
ISSN: |
1679-0359 |
DOI: |
10.5433/1679-0359.2021v42n1p361 |
Idioma: |
Português |
Conteúdo: |
This study proposes to examine the economic viability of implementing the necessary infrastructure for the recycling of bedding sand from a free-stall facility in a milk production system in southern Minas Gerais, Brazil. In specific terms, the total production cost (TC), total operating cost (TOC) and effective operating cost (EOC) of a cubic meter of recycled sand were estimated in order to estimate the total sand consumption for the free-stall system and per bed year-1 as well as the equilibrium point of the amount of recycled sand, in cubic meters. The experiment was carried out on a farm located in the south of Minas Gerais from January 2016 to December 2017. Three scenarios were analyzed by the tree-point estimation method (MOP - most likely, optimistic, and pessimistic). Utilization of 85%, 95% and 75% of the recycled sand was considered for scenarios 1, 2 and 3, respectively. In all of them, the value charged per cubic meter of sand by a supplier close to the farm was considered. Monte Carlo simulation was also carried out with hurdle rates (HR) of up to 90%. Under the studied conditions, sand recycling showed to be economically viable in all scenarios, with positive net present values (NPV), internal rates of return above the HR, simple and discounted payback below the 10-year horizon, and satisfactory cost benefit-1 ratios (greater than 1). The EOC of one cubic meter of recycled sand was estimated at R$5.04, R$4.51 and R$5.72 for scenarios 1, 2 and 3, respectively, whereas the average TC, considering all scenarios, was R$6.84 (+0.81), which is less than the acquisition price of R$28.57 at the sand extraction site. The TC was R$37,219.51 and R$34,637.74 for the scenarios with HR of 8.50 and 6.99%, respectively, whereas TOC was R$22,572.08 in all analyzed scenarios. The estimated total annual sand consumption by the free-stall system was 526.44 m³, with an estimated average of 1.23 m³ (+0.28) bed-1 year-1. All Monte Carlo simulation models showed positive NPV as well as HR of up to 90%, which reflect a high probability of positive NPV. MenosThis study proposes to examine the economic viability of implementing the necessary infrastructure for the recycling of bedding sand from a free-stall facility in a milk production system in southern Minas Gerais, Brazil. In specific terms, the total production cost (TC), total operating cost (TOC) and effective operating cost (EOC) of a cubic meter of recycled sand were estimated in order to estimate the total sand consumption for the free-stall system and per bed year-1 as well as the equilibrium point of the amount of recycled sand, in cubic meters. The experiment was carried out on a farm located in the south of Minas Gerais from January 2016 to December 2017. Three scenarios were analyzed by the tree-point estimation method (MOP - most likely, optimistic, and pessimistic). Utilization of 85%, 95% and 75% of the recycled sand was considered for scenarios 1, 2 and 3, respectively. In all of them, the value charged per cubic meter of sand by a supplier close to the farm was considered. Monte Carlo simulation was also carried out with hurdle rates (HR) of up to 90%. Under the studied conditions, sand recycling showed to be economically viable in all scenarios, with positive net present values (NPV), internal rates of return above the HR, simple and discounted payback below the 10-year horizon, and satisfactory cost benefit-1 ratios (greater than 1). The EOC of one cubic meter of recycled sand was estimated at R$5.04, R$4.51 and R$5.72 for scenarios 1, 2 and 3, respectively,... Mostrar Tudo |
Palavras-Chave: |
Análise de cenários; Bovinocultura leiteira; Dairy cattle farming; Indicadores de rentabilidade; Profitability indicators; Reuse; Reuso; Scenario analysis; Sustainability; Sustentabilidade. |
Categoria do assunto: |
E Economia e Indústria Agrícola |
URL: |
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/1137670/1/EconomicViabilityImplementing.pdf
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Marc: |
LEADER 03172naa a2200361 a 4500 001 2137670 005 2021-12-13 008 2021 bl uuuu u00u1 u #d 022 $a1679-0359 024 7 $a10.5433/1679-0359.2021v42n1p361$2DOI 100 1 $aLOPES, M. A. 245 $aEconomic viability of implementing an infrastructure for recycling bedding sand from a free-stall facility for dairy cows.$h[electronic resource] 260 $c2021 520 $aThis study proposes to examine the economic viability of implementing the necessary infrastructure for the recycling of bedding sand from a free-stall facility in a milk production system in southern Minas Gerais, Brazil. In specific terms, the total production cost (TC), total operating cost (TOC) and effective operating cost (EOC) of a cubic meter of recycled sand were estimated in order to estimate the total sand consumption for the free-stall system and per bed year-1 as well as the equilibrium point of the amount of recycled sand, in cubic meters. The experiment was carried out on a farm located in the south of Minas Gerais from January 2016 to December 2017. Three scenarios were analyzed by the tree-point estimation method (MOP - most likely, optimistic, and pessimistic). Utilization of 85%, 95% and 75% of the recycled sand was considered for scenarios 1, 2 and 3, respectively. In all of them, the value charged per cubic meter of sand by a supplier close to the farm was considered. Monte Carlo simulation was also carried out with hurdle rates (HR) of up to 90%. Under the studied conditions, sand recycling showed to be economically viable in all scenarios, with positive net present values (NPV), internal rates of return above the HR, simple and discounted payback below the 10-year horizon, and satisfactory cost benefit-1 ratios (greater than 1). The EOC of one cubic meter of recycled sand was estimated at R$5.04, R$4.51 and R$5.72 for scenarios 1, 2 and 3, respectively, whereas the average TC, considering all scenarios, was R$6.84 (+0.81), which is less than the acquisition price of R$28.57 at the sand extraction site. The TC was R$37,219.51 and R$34,637.74 for the scenarios with HR of 8.50 and 6.99%, respectively, whereas TOC was R$22,572.08 in all analyzed scenarios. The estimated total annual sand consumption by the free-stall system was 526.44 m³, with an estimated average of 1.23 m³ (+0.28) bed-1 year-1. All Monte Carlo simulation models showed positive NPV as well as HR of up to 90%, which reflect a high probability of positive NPV. 653 $aAnálise de cenários 653 $aBovinocultura leiteira 653 $aDairy cattle farming 653 $aIndicadores de rentabilidade 653 $aProfitability indicators 653 $aReuse 653 $aReuso 653 $aScenario analysis 653 $aSustainability 653 $aSustentabilidade 700 1 $aDEMEU, F. A. 700 1 $aREIS, E. M. B. 700 1 $aLIMA, A. L. R. 700 1 $aCARVALHO, F. DE M. 700 1 $aPALHARES, J. C. P. 700 1 $aCOSTA, G. M. DA 700 1 $aPINHEIRO, M. V. G. 700 1 $aDEMEU, A. A. 773 $tSemina$gv.42, n.1, p.361-374, jan./fev. 2021.
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