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 | Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
24/08/2023 |
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Data da última atualização: |
08/11/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GALANTE, P.; CAMPOS, G. A. A.; MOSER, J. C. G.; MARTINS, D. B.; CABRERA, M. P. dos S.; RANGEL, M.; COELHO, L. C.; SIMON, K. S.; AMADO, V. M.; MULLER, J. de A. I.; KOEHBACH, J.; LOHMAN, R.-J.; CABOT, P. J.; VETTER, I.; CRAIK, D. J.; TOFFOLI-KADRI, M. C.; MONGE-FUENTES, V.; GOULART, J. T.; SCHWARTZ, E. F.; SILVA, L. P. da; BOCCA, A. L.; MORTARI, M. R. |
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Afiliação: |
PRISCILLA GALANTE, University of Brasília; GABRIEL A. A. CAMPOS, University of Brasília; JACQUELINE C. G. MOSER, University of Brasília; DANUBIA B. MARTINS, São Paulo State University; MARCIA P. DOS SANTOS CABRERA, São Paulo State University; MARISA RANGEL, Butantan Institute, Sao Paulo; LUIZA C. COELHO, University of Brasilia; KARINA S. SIMON, University of Brasilia; VERONICA M. AMADO, University of Brasilia; JESSICA DE A. I. MULLER, Federal University of Mato Grosso do Sul; JOHANNES KOEHBACH, The University of Queensland, Australia; RINK‑JAN LOHMAN, The University of Queensland, Australia; PETER J. CABOT, The University of Queensland, ,Australia; IRINA VETTER, The University of Queensland, ,Australia; DAVID J. CRAIK, The University of Queensland, Australia; MONICA C. TOFFOLI-KADRI, Federal University of Mato Grosso do Sul; VICTORIA MONGE-FUENTES, University of Brasília; JAIR T. GOULART, University of Brasília; ELISABETH F. SCHWARTZ, University of Brasília; LUCIANO PAULINO DA SILVA, Cenargen; ANAMELIA L. BOCCA, University of Brasilia; MÁRCIA R. MORTARI, University of Brasília. |
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Título: |
Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Scientific Reports, v. 13, 2023. Article number: 12491. |
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DOI: |
https://doi.org/10.1038/s41598-023-38828-w |
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Idioma: |
Inglês |
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Notas: |
Na publicação: Luciano P. Silva. |
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Palavras-Chave: |
Animal venoms; Anti-inflammatory; Antiepileptic; Ntinociceptive. |
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Thesaurus Nal: |
Parachartergus fraternus. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01323naa a2200445 a 4500
001 2156106
005 2023-11-08
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1038/s41598-023-38828-w$2DOI
100 1 $aGALANTE, P.
245 $aExploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom.$h[electronic resource]
260 $c2023
500 $aNa publicação: Luciano P. Silva.
650 $aParachartergus fraternus
653 $aAnimal venoms
653 $aAnti-inflammatory
653 $aAntiepileptic
653 $aNtinociceptive
700 1 $aCAMPOS, G. A. A.
700 1 $aMOSER, J. C. G.
700 1 $aMARTINS, D. B.
700 1 $aCABRERA, M. P. dos S.
700 1 $aRANGEL, M.
700 1 $aCOELHO, L. C.
700 1 $aSIMON, K. S.
700 1 $aAMADO, V. M.
700 1 $aMULLER, J. de A. I.
700 1 $aKOEHBACH, J.
700 1 $aLOHMAN, R.-J.
700 1 $aCABOT, P. J.
700 1 $aVETTER, I.
700 1 $aCRAIK, D. J.
700 1 $aTOFFOLI-KADRI, M. C.
700 1 $aMONGE-FUENTES, V.
700 1 $aGOULART, J. T.
700 1 $aSCHWARTZ, E. F.
700 1 $aSILVA, L. P. da
700 1 $aBOCCA, A. L.
700 1 $aMORTARI, M. R.
773 $tScientific Reports$gv. 13, 2023. Article number: 12491.
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Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
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| Acesso ao texto completo restrito à biblioteca da Embrapa Semiárido. Para informações adicionais entre em contato com cpatsa.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Semiárido. |
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Data corrente: |
29/05/2019 |
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Data da última atualização: |
02/12/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
CAMARGO, A. C. de; BIASOTO, A. C. T.; SCHWEMBER, A. R.; GRANADO, D.; RASERA, G. B.; FRANCHIN, M.; ROSALEN, P. L.; ALENCAR, S. M.; SHAHIDI, F. |
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Afiliação: |
Adriano Costa de Camargo; ALINE TELLES BIASOTO MARQUES, CPATSA; Andrés R. Schwember; Daniel Granato; Gabriela Boscariol Rasera; Marcelo Franchin; Pedro L. Rosalen; Severino Matias Alencar; Fereidoon Shahidi. |
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Título: |
Should we ban total phenolics and antioxidant screening methods? The link between antioxidant potential and activation of NF-KB using phenolic compounds from grape by-products. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Food Chemistry, v. 290, p. 229-238, 2019. |
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DOI: |
10.1016/j.foodchem.2019.03.145 |
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Idioma: |
Inglês |
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Conteúdo: |
Free radical imbalance is associated with several chronic diseases. However, recent controversies have put in check the validity of colorimetric methods to screen the functionality of polyphenols. Therefore, in this study two antioxidant methods, based on chemical reactions, were tested for their ability in anticipating the reduction of the activation of NF-κB using LPS-activated RAW 264.7 macrophages, selected as a biological model. Grape processing by-products from winemaking showed higher total phenolic content (TPC), antioxidant capacity towards peroxyl radical (31.1%) as well as reducing power (39.5%) than those of grape juice by-products. The same trend was observed when these samples were tested against LPS-activated RAW 264.7 macrophages by reducing the activation NF-κB. Feedstocks containing higher TPC and corresponding ORAC and FRAP results translated to higher reduction in the activation of NF-κB (36.5%). Therefore, this contribution demonstrates that colorimetric methods are still important screening tools owing their simplicity and widespread application. |
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Palavras-Chave: |
Compostos fenólicos; Fenólicos bioativos; Redução de poder antioxidante férrico. |
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Thesagro: |
Subproduto; Uva. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02041naa a2200289 a 4500
001 2109420
005 2019-12-02
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1016/j.foodchem.2019.03.145$2DOI
100 1 $aCAMARGO, A. C. de
245 $aShould we ban total phenolics and antioxidant screening methods? The link between antioxidant potential and activation of NF-KB using phenolic compounds from grape by-products.$h[electronic resource]
260 $c2019
520 $aFree radical imbalance is associated with several chronic diseases. However, recent controversies have put in check the validity of colorimetric methods to screen the functionality of polyphenols. Therefore, in this study two antioxidant methods, based on chemical reactions, were tested for their ability in anticipating the reduction of the activation of NF-κB using LPS-activated RAW 264.7 macrophages, selected as a biological model. Grape processing by-products from winemaking showed higher total phenolic content (TPC), antioxidant capacity towards peroxyl radical (31.1%) as well as reducing power (39.5%) than those of grape juice by-products. The same trend was observed when these samples were tested against LPS-activated RAW 264.7 macrophages by reducing the activation NF-κB. Feedstocks containing higher TPC and corresponding ORAC and FRAP results translated to higher reduction in the activation of NF-κB (36.5%). Therefore, this contribution demonstrates that colorimetric methods are still important screening tools owing their simplicity and widespread application.
650 $aSubproduto
650 $aUva
653 $aCompostos fenólicos
653 $aFenólicos bioativos
653 $aRedução de poder antioxidante férrico
700 1 $aBIASOTO, A. C. T.
700 1 $aSCHWEMBER, A. R.
700 1 $aGRANADO, D.
700 1 $aRASERA, G. B.
700 1 $aFRANCHIN, M.
700 1 $aROSALEN, P. L.
700 1 $aALENCAR, S. M.
700 1 $aSHAHIDI, F.
773 $tFood Chemistry$gv. 290, p. 229-238, 2019.
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Embrapa Semiárido (CPATSA) |
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