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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/11/2002 |
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Data da última atualização: |
06/11/2002 |
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Autoria: |
DALEY, C. A.; SAKURAI, H.; ADAMS, B. M.; ADAMS, T. E. |
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Título: |
Effect of stress-like concentrations of cortisol on gonadotroph function in orchidectomized sheep. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 60, n. 1, p. 158-163, 1999. |
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Idioma: |
Inglês |
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Conteúdo: |
The effect of stress-like concentrations of cortisol (C) on the feedback potency of estradiol (E,) was assessed using 32 orchidectomized sheep (wethers) assigned at random to 1 of 4 treatment groups in a 2 x 2 factorial design. Wethers received C (3.6 mg/50 kg per hour; groups 2 and 4) or a comparable volume of C delivery vehicle (groups 1 and 3) as a continuous infusion for 7 days. During the final 48 h of infusion, wethers received E2 (0.3 ug/50 kg/h; groups 3 and 4) or E2 delivery vehicle (groups 1 and 2). The pattern of LH secretion was assessed during a 4 h period of intensive blood collection beginning 44 h after initiation of E2 infusion. Gonadotroph responsiveness (LH secretion induced by GnRH challenge [500 ng, i.v.]) was determined 48 h after E2 delivery was begun. Although lhe frequency of secretory episodes of LH was not affected (p > 0.05) by infusion of C or E2 alone, LH pulse frequency was significantly decreased in wethers receiving C and E2 in combination. In contrast, neither the magnitude of basal gonadotroph responsiveness nor the extent of E2-dependent augmentation of responsiveness was significantly affected by stress-like concentrations of C. In a second experiment, the effect of C on the magnitude of E2-induced in- crease in pituitary concentration of GnRH receptor and GnRH receptor mRNA was assessed using 32 additional wethers. Continuous infusion of E2 for 48 h increased (p < 0.05) tissue concentrations of GnRH receptor and GnRH receptor mRNA. Con- current delivery of C did not affect (p > 0.05) E2-induced in- crease in GnRH receptor mRNA but significantly reduced the magnitude of the E2-dependent increase in pituitary concentration of GnRH receptor. Collectively, these data indicate that stress-like concentrations of C enhance the negative feedback potency of E2 and reduce estrogen-dependent augmentation of the concentration of GnRH receptor in pituitary tissue. MenosThe effect of stress-like concentrations of cortisol (C) on the feedback potency of estradiol (E,) was assessed using 32 orchidectomized sheep (wethers) assigned at random to 1 of 4 treatment groups in a 2 x 2 factorial design. Wethers received C (3.6 mg/50 kg per hour; groups 2 and 4) or a comparable volume of C delivery vehicle (groups 1 and 3) as a continuous infusion for 7 days. During the final 48 h of infusion, wethers received E2 (0.3 ug/50 kg/h; groups 3 and 4) or E2 delivery vehicle (groups 1 and 2). The pattern of LH secretion was assessed during a 4 h period of intensive blood collection beginning 44 h after initiation of E2 infusion. Gonadotroph responsiveness (LH secretion induced by GnRH challenge [500 ng, i.v.]) was determined 48 h after E2 delivery was begun. Although lhe frequency of secretory episodes of LH was not affected (p > 0.05) by infusion of C or E2 alone, LH pulse frequency was significantly decreased in wethers receiving C and E2 in combination. In contrast, neither the magnitude of basal gonadotroph responsiveness nor the extent of E2-dependent augmentation of responsiveness was significantly affected by stress-like concentrations of C. In a second experiment, the effect of C on the magnitude of E2-induced in- crease in pituitary concentration of GnRH receptor and GnRH receptor mRNA was assessed using 32 additional wethers. Continuous infusion of E2 for 48 h increased (p < 0.05) tissue concentrations of GnRH receptor and GnRH receptor mRNA. Con- ... Mostrar Tudo |
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Palavras-Chave: |
Gonadotropina. |
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Thesagro: |
Hormônio; Ovino; Stress. |
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Thesaurus Nal: |
cortisol. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02515naa a2200217 a 4500
001 1528806
005 2002-11-06
008 1999 bl uuuu u00u1 u #d
100 1 $aDALEY, C. A.
245 $aEffect of stress-like concentrations of cortisol on gonadotroph function in orchidectomized sheep.
260 $c1999
520 $aThe effect of stress-like concentrations of cortisol (C) on the feedback potency of estradiol (E,) was assessed using 32 orchidectomized sheep (wethers) assigned at random to 1 of 4 treatment groups in a 2 x 2 factorial design. Wethers received C (3.6 mg/50 kg per hour; groups 2 and 4) or a comparable volume of C delivery vehicle (groups 1 and 3) as a continuous infusion for 7 days. During the final 48 h of infusion, wethers received E2 (0.3 ug/50 kg/h; groups 3 and 4) or E2 delivery vehicle (groups 1 and 2). The pattern of LH secretion was assessed during a 4 h period of intensive blood collection beginning 44 h after initiation of E2 infusion. Gonadotroph responsiveness (LH secretion induced by GnRH challenge [500 ng, i.v.]) was determined 48 h after E2 delivery was begun. Although lhe frequency of secretory episodes of LH was not affected (p > 0.05) by infusion of C or E2 alone, LH pulse frequency was significantly decreased in wethers receiving C and E2 in combination. In contrast, neither the magnitude of basal gonadotroph responsiveness nor the extent of E2-dependent augmentation of responsiveness was significantly affected by stress-like concentrations of C. In a second experiment, the effect of C on the magnitude of E2-induced in- crease in pituitary concentration of GnRH receptor and GnRH receptor mRNA was assessed using 32 additional wethers. Continuous infusion of E2 for 48 h increased (p < 0.05) tissue concentrations of GnRH receptor and GnRH receptor mRNA. Con- current delivery of C did not affect (p > 0.05) E2-induced in- crease in GnRH receptor mRNA but significantly reduced the magnitude of the E2-dependent increase in pituitary concentration of GnRH receptor. Collectively, these data indicate that stress-like concentrations of C enhance the negative feedback potency of E2 and reduce estrogen-dependent augmentation of the concentration of GnRH receptor in pituitary tissue.
650 $acortisol
650 $aHormônio
650 $aOvino
650 $aStress
653 $aGonadotropina
700 1 $aSAKURAI, H.
700 1 $aADAMS, B. M.
700 1 $aADAMS, T. E.
773 $tBiology of Reproduction$gv. 60, n. 1, p. 158-163, 1999.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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Registro Completo
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Biblioteca(s): |
Embrapa Clima Temperado. |
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Data corrente: |
19/10/2017 |
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Data da última atualização: |
19/10/2017 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
ZORZO, B.; TRINDADE, C. T. O.; FAGUNDES, J. P.; DUARTE, A. da F.; CUNHA, U. SILVA da; RASEIRA, M. do C. B.; NAVA, D. E. |
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Afiliação: |
ZORZO, BRUNO; CUNHA, UEMERSON SILVA DA; MARIA DO CARMO BASSOLS RASEIRA, CPACT; DORI EDSON NAVA, CPACT. |
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Título: |
Ocorrência de ácaros em Rubus spp. em Pelotas. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
In: CONGRESSO DE INICIAÇÃO CIENTÍFICA, 26.; ENCONTRO DE PÓS-GRADUAÇÃO UFPEL, 19.; SEMANA INTEGRADA DE ENSINO, PESQUISA E EXTENSÃO, 3., 2016, Pelotas. Anais... Pelotas: UFPel, 2017. |
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Idioma: |
Português |
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Palavras-Chave: |
Rubus spp. |
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Categoria do assunto: |
-- |
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URL: |
https://www.alice.cnptia.embrapa.br/alice/bitstream/doc/1077668/1/MariadocarmoOcorrenciadeacaros...CIC2017.pdf
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Marc: |
LEADER 00665nam a2200181 a 4500
001 2077668
005 2017-10-19
008 2017 bl uuuu u00u1 u #d
100 1 $aZORZO, B.
245 $aOcorrência de ácaros em Rubus spp. em Pelotas.$h[electronic resource]
260 $aIn: CONGRESSO DE INICIAÇÃO CIENTÍFICA, 26.; ENCONTRO DE PÓS-GRADUAÇÃO UFPEL, 19.; SEMANA INTEGRADA DE ENSINO, PESQUISA E EXTENSÃO, 3., 2016, Pelotas. Anais... Pelotas: UFPel$c2017
653 $aRubus spp
700 1 $aTRINDADE, C. T. O.
700 1 $aFAGUNDES, J. P.
700 1 $aDUARTE, A. da F.
700 1 $aCUNHA, U. SILVA da
700 1 $aRASEIRA, M. do C. B.
700 1 $aNAVA, D. E.
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Embrapa Clima Temperado (CPACT) |
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