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Registros recuperados : 86 | |
41. |  | LIMA, B. L.; LIMA, A. O. de; MOKRY, F. B.; BRESSANI, F.; MALAGO JUNIOR, W.; HIGA, R. H.; MUDADU, M. de A.; REGITANO, L. C. de A. Validação de um SNP associado à área de olho de lombo em uma população de animais Canchim In: JORNADA CIENTÍFICA - EMBRAPA SÃO CARLOS, 4., 2012, São Carlos, SP. Anais... São Carlos: Embrapa Instrumentação: Embrapa Pecuária Sudeste, 2012. 145 p. Editores técnicos: João de Mendonça Naime, Lucimara Aparecida Forato, Maria Alice Martins, Ladislau Marcelino Rabello, Rubens Bernardes Filho. (Embrapa Instrumentação. Documentos, 56). p. 43 Biblioteca(s): Embrapa Pecuária Sudeste. |
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42. |  | SOUZA, M.; NICIURA, S. C. M.; TIZIOTO, P.; IBELLI, A. M. G.; GASPARIN, G.; MALAGO JUNIOR, W.; MUDADU, M. de A.; BARIONI JUNIOR, W.; COUTINHO, L.; REGITANO, L. C. de A. Allelic and parental-specific expression on the KCNJ11 gene in cattle. In: SUMMER SCHOOL ON CHROMATIN AND SYSTEMS BIOLOGY, 2013, Spetses. Proceedings... Spetese: Chromatin and Systems Biology, 2013. p. 147 Biblioteca(s): Embrapa Pecuária Sudeste. |
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43. |  | KASARAPU, P.; PORTO NETO, L. R.; FORTES, M. R. S.; LEHNERT, S. A.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A.; GEORGE, A.; REVERTER, A. The Bos taurus-Bos indicus balance in fertility and milk related genes. PLOS one, v. 12, n. 8, p. 1-20, 2017. Biblioteca(s): Embrapa Pecuária Sudeste. |
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44. |  | ALEXANDRE, P. A.; GOMES, R. da C.; SANTANA, M. H. A.; SILVA, S. L.; MUDADU, M. de A.; REGITANO, L. C. de A.; MEIRELLES, F. V.; FERRAZ, J. B. S.; FUKUMASU, H. Bovine NR1I3 gene polymorphisms and its association with feed efficiency traits in Nellore cattle. Meta Gene, v. 2, p. 206-217, 2014 Biblioteca(s): Embrapa Pecuária Sudeste. |
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45. |  | SOMAVILLA, A. L.; MOTA, M. D. S.; ALENCAR, M. M. de; ROSA, A. do N.; COUTINHO, L. L.; TULLIO, R. R.; MUDADU, M. de A.; REGITANO, L. C. de A. Genome-wide association study of weight gain in feedlot Nellore cattle: comparison of single nucleotide polymorphism and haplotype blocks approaches. In: ANNUAL MEETING BRAZILIAN SOCIETY OF ANIMAL SCIENCE, 50., 2013, Campinas. The integration of Knowledge in animal production - Abstracts. Campinas: SBZ, 2013. 1 CD-ROM Biblioteca(s): Embrapa Pecuária Sudeste. |
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46. |  | BUSS, C. E.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; MUDADU, M. de A.; CESAR, A. S. M.; VENTURA, R. V.; AFONSO, J.; LIMA, A. O. de; COUTINHO, L. L.; TULLIO, R. R.; REGITANO, L. C. de A. Genome-wide efficient mixed-model study for meat quality in Nellore cattle. Journal of Animal Science, v. 94, e-suppl. 5; Journal of Dairy Science, v. 99, e-suppl. 1, p. 159, jul. 2016. Biblioteca(s): Embrapa Pecuária Sudeste. |
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47. |  | BUSS, C. E.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; MUDADU, M. de A.; CESAR, A. S. M.; VENTURA, R. V.; AFONSO, J.; LIMA, A. O. D.; COUTINHO, L. L.; TULLIO, R. R.; REGITANO, L. C. de A. Genome-wide efficient mixed-model study for meat quality in Nellore cattle. Journal of Animal Science, v. 94, p. 428-429, 2016. Supplement 5. Na publicação: M. A. Mudadu. Biblioteca(s): Embrapa Informática Agropecuária. |
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48. |  | SOMAVILLA, A. L.; HIGA, R. H.; ROSA, A. do N.; SIQUEIRA, F.; SILVA, L. O. C. da; TORRES JUNIOR, R. A. de A.; MUDADU, M. de A.; ALENCAR, M. M. de; REGITANO, L. C. de A. A genome-wide scan for selection signatures in Nellore cattle. Animal Genetics, v. 45, n. 6, p. 771-781, 2014. Biblioteca(s): Embrapa Gado de Corte. |
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49. |  | SOMAVILLA, A. L.; SONSTEGARD, T. S.; HIGA, R. H.; ROSA, A. do N.; SIQUEIRA, F.; SILVA, L. O. C.; TORRES JÚNIOR, R. A. de A.; COUTINHO, L. L.; MUDADU, M. de A.; ALENCAR, M. M.; REGITANO, L. C. A. A genome-wide scan for selection signatures in Nellore cattle. Animal Genetics, Oxford, v. 45, n. 6, p. 771-781, 2014. Biblioteca(s): Embrapa Informática Agropecuária; Embrapa Pecuária Sudeste. |
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50. |  | SOMAVILLA, A. L.; REGITANO, L. C. de A.; ROSA, G. J. M.; MOKRY, F. B.; MUDADU, M. de A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; SOUZA, M. M.; COUTINHO, L. L.; MUNARI, D. P. Genome-enabled prediction of breeding values for feedlot average daily weight gain in nelore cattle. G3: Genes, Genomes, Genetics, v. 7, n. 6, p. 1855-1859, 2017. Na publicação: Luciana C. A. Regitano. Biblioteca(s): Embrapa Informática Agropecuária; Embrapa Pecuária Sudeste. |
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51. |  | CESAR, A. S. M.; REGITANO, L. C. de A.; LANNA, D. P. D.; POLETI, M. D.; KOLTES, J. E.; REECY, J. M.; FRITZ-WATERS, E.; KRAMER, L.; GARRICK, D.; MUDADU, M. de A.; TULLIO, R. R.; COUTINHO, L. L. Expression quantitative trait loci (eQTL) hotspot regions from whole genome analysis of Nellore steers. In: PLANT AND ANIMAL GENOME CONFERENCE, 24., 2016, San Diego. Anais... San Diego: PAG, 2016. Biblioteca(s): Embrapa Pecuária Sudeste. |
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52. |  | TIZIOTO, P. C.; GASPARIN, G.; COUTINHO, L. L.; MOURÃO, G. B.; MUDADU, M. de A.; SOUZA, M. M.; MALAGO JUNIOR, W.; DONATONI, F. A. B.; TULLIO, R. R.; NASSU, R. T.; REGITANO, L. C. de A. MyoD1 expression levels affect meat tenderness in Nellore beef cattle. In:WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOK PRODUCTION, 10;. 2014, Vancouver. Proceedings... Vancouver: American Society of animal Science, 2014 Biblioteca(s): Embrapa Pecuária Sudeste. |
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53. |  | DINIZ, M. R. V.; PAIVA, A. L. B.; GUERRA-DUARTE, C.; NISHIYAMA JÚNIOR, M. Y.; MUDADU, M. de A.; OLIVEIRA, U. de; BORGES, M. H.; YATES, J. R.; JUNQUEIRA-DE-AZEVEDO, I. de. An overview of Phoneutria nigriventer spider venom using combined transcriptomic and proteomic approaches. PLoS ONE, v. 13, n. 8, p. 1-29, 2018. Artigo e0200628. Na publicação: Mauricio A. Mudadu. Biblioteca(s): Embrapa Informática Agropecuária. |
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54. |  | TIZIOTO, P. C.; GROMBONI, C. F.; NOGUEIRA, A. R. de A.; SOUZA, M. M. de; MUDADU, M. de A.; THOLON, P.; ROSA, A. do N.; TULLIO, R. R.; MEDEIROS, S. R. de; NASSU, R. T.; REGITANO, L. C. de A. Calcium and potassium content in beef: In fluences on tenderness and associations with molecular markers in Nellore cattle. Meat Science, v. 96, p. 436-440, 2014. Biblioteca(s): Embrapa Pecuária Sudeste. |
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55. |  | TIZIOTO, P. C.; GROMBONI, C. F.; NOGUEIRA, A. R. de A.; SOUZA, M. M. de; MUDADU, M. de A.; THOLON, P.; ROSA, A. do N.; TULLIO, R. R.; MEDEIROS, S. R. de; NASSU, R. T.; REGITANO, L. C. de A. Calcium and potassium content in beef: Influences on tenderness and associations with molecular markers in Nellore cattle. Meat Science, v. 96, n. 1, p. 436-440, January 2014 Biblioteca(s): Embrapa Gado de Corte. |
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56. |  | MOKRY, F. B.; LIMA, A. O.; MUDADU, M. de A.; HIGA, R. H.; MEIRELLES, S. L. C.; SILVA, M. V. G. B.; CARDOSO, F. F.; NICIURA, S. C. M. Descriptive analysis of haplotypes in a population of Canchim beef cattle. In: CONGRESSO BRASILEIRO DE GENÉTICA, 58., 2012, Foz do Iguaçu. Anais... Foz do Igauaçu: SBG, 2012. 1 CD-ROM Biblioteca(s): Embrapa Pecuária Sudeste. |
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57. |  | AZEVEDO, D. A. A. de; MONTEIRO, J. P.; PINHEIRO, R. R.; MUDADU, M. de A.; ANDRIOLI, A.; ARAÚJO, J. F.; SOUSA, A. L. M. de; SIDER, L. H.; PEIXOTO, R. M.; TEIXEIRA, M. F. da S. Molecular characterization of circulating strains of small ruminant lentiviruses in Brazil based on complete gag and pol genes. Small Ruminant Research, v. 177, p. 160-166, 2019. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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58. |  | CHUD, T. C. S.; VENTURA, R. V.; SCHENKEL, F. S.; CARVALHEIRO, R.; BUZANSKAS, M. E.; ROSA, J. O.; MUDADU, M. de A.; SILVA, M. V. G. B.; MARCONDES, C. R.; REGITANO, L. C. de A.; MUNARI, D. P. Strategies for genotype imputation in composite beef cattle BMC Genetics, v. 16, p. 99, 2015. 10 p. Biblioteca(s): Embrapa Gado de Leite; Embrapa Pecuária Sudeste. |
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59. |  | BRESSANI, F. A.; TIZIOTO, P. C.; GIGLIOTI, R.; MEIRELLHES, S. L. C.; COUTINHO, L. L.; BENVENUTI, C. L.; MALAGO JUNIOR, W.; MUDADU, M. de A.; VIEIRA, L. da S.; ZAROS, L. G.; CARRILHO, E.; REGITANO, L. C. de A. Single nucleotide polymorphisms in candidate genes associated with gastrointestinal nematode infection in goats. Genetics and Molecular Research, v. 13, n. 4, p. 8530-8436, Oct. 2014. Biblioteca(s): Embrapa Caprinos e Ovinos; Embrapa Pecuária Sudeste. |
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60. |  | SOUZA, M. M. de; NICIURA, S. C. M.; TIZIOTO, P. C.; IBELLI, A. M. G.; GASPARIN, G.; ROCHA, M. I. P.; DONATONI, F. A. B.; MALAGO JUNIOR, W.; DINIZ, W. J. S.; OLIVEIRA, P. S. N. de; LIMA, A. O.; MUDADU, M. de A.; BARIONI JUNIOR, W.; COUTINHO, L. L.; REGITANO, L. C. de A. Allele-and parent-of-origin-specific effects on expression of the KCNJ11 gene: a candidate for meat tenderness in cattle. Genetics and Molecular Research, v. 15, n. 2, p. 1-9, Aug. 2016. Biblioteca(s): Embrapa Informática Agropecuária; Embrapa Pecuária Sudeste. |
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Registros recuperados : 86 | |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
04/09/2017 |
Data da última atualização: |
21/05/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
KASARAPU, P.; PORTO NETO, L. R.; FORTES, M. R. S.; LEHNERT, S. A.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A.; GEORGE, A.; REVERTER, A. |
Afiliação: |
Parthan Kasarapu, Agriculture and Food/CSIRO; Laercio Ribeiro Porto Neto, Agriculture and Food/CSIRO; Marina R. S. Fortes, The University of Queensland; Sigrid A. Lehnert, Agriculture and Food/CSIRO; MAURICIO DE ALVARENGA MUDADU, CNPTIA; Luiz Lehmann Coutinho, ESALQ/USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; Andrew George, Agriculture and Food/CSIRO; Antonio Reverter, Agriculture and Food/CSIRO. |
Título: |
The Bos taurus-Bos indicus balance in fertility and milk related genes. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
PLOS one, v. 12, n. 8, p. 1-20, 2017. |
DOI: |
https://doi.org/10.1371/journal.pone.0181930 |
Idioma: |
Inglês |
Conteúdo: |
Numerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene?s contribution to the Bos taurus-Bos indicus axis. We used deviation from HWE, contribution to Bos indicus content and association to fertility traits to select 1,284 genes. With this set, we developed a co-heterozygosity network where the group of genes annotated as fertility-related had significantly higher Bos indicus content compared to other functional classes of genes, while the group of genes associated with milk production had significantly higher Bos taurus content. The network analysis resulted in capturing novel gene associations of relevance to bovine domestication events. We report transcription factors that are likely to regulate genes associated with cattle domestication and tropical adaptation. Our pipeline can be generalized to any scenarios where population structure requires scrutiny at the molecular level, particularly in the presence of a priori set of genes known to impact a phenotype of evolutionary interest such as fertility. MenosNumerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene?s contribution to the Bos taurus-Bos indicus axis. We used deviation from HWE, contribution to Bos indicus content and association to fertility traits to select 1,284 genes. With this set, we developed a co-heterozygosity network where the group of genes annotated as fertility-related had significantly higher Bos indicus content compared to other functional classes of genes, while the group of genes associated with milk production had significantly higher Bos taurus content. The network analysis resulted in capturing novel gene associations of relevance to bovine domestication events. We report transcription factors that are likely to regulate genes associated with cattle domestication and tropical adaptation. Our pipeline can be generalized to any scenarios w... Mostrar Tudo |
Palavras-Chave: |
Hardy-Weinberg equilibrium. |
Thesagro: |
Bos Indicus; Bos Taurus. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
URL: |
http://ainfo.cnptia.embrapa.br/digital/bitstream/item/163369/1/journal.pone.0181930.pdf
|
Marc: |
LEADER 02467naa a2200265 a 4500 001 2074938 005 2019-05-21 008 2017 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1371/journal.pone.0181930$2DOI 100 1 $aKASARAPU, P. 245 $aThe Bos taurus-Bos indicus balance in fertility and milk related genes.$h[electronic resource] 260 $c2017 520 $aNumerical approaches to high-density single nucleotide polymorphism (SNP) data are often employed independently to address individual questions. We linked independent approaches in a bioinformatics pipeline for further insight. The pipeline driven by heterozygosity and Hardy-Weinberg equilibrium (HWE) analyses was applied to characterize Bos taurus and Bos indicus ancestry. We infer a gene co-heterozygosity network that regulates bovine fertility, from data on 18,363 cattle with genotypes for 729,068 SNP. Hierarchical clustering separated populations according to Bos taurus and Bos indicus ancestry. The weights of the first principal component were subjected to Normal mixture modelling allowing the estimation of a gene?s contribution to the Bos taurus-Bos indicus axis. We used deviation from HWE, contribution to Bos indicus content and association to fertility traits to select 1,284 genes. With this set, we developed a co-heterozygosity network where the group of genes annotated as fertility-related had significantly higher Bos indicus content compared to other functional classes of genes, while the group of genes associated with milk production had significantly higher Bos taurus content. The network analysis resulted in capturing novel gene associations of relevance to bovine domestication events. We report transcription factors that are likely to regulate genes associated with cattle domestication and tropical adaptation. Our pipeline can be generalized to any scenarios where population structure requires scrutiny at the molecular level, particularly in the presence of a priori set of genes known to impact a phenotype of evolutionary interest such as fertility. 650 $aBos Indicus 650 $aBos Taurus 653 $aHardy-Weinberg equilibrium 700 1 $aPORTO NETO, L. R. 700 1 $aFORTES, M. R. S. 700 1 $aLEHNERT, S. A. 700 1 $aMUDADU, M. de A. 700 1 $aCOUTINHO, L. L. 700 1 $aREGITANO, L. C. de A. 700 1 $aGEORGE, A. 700 1 $aREVERTER, A. 773 $tPLOS one$gv. 12, n. 8, p. 1-20, 2017.
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