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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
15/09/2015 |
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Data da última atualização: |
06/09/2021 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
BEZERRA JUNIOR, R. Q.; ELOY, A. M. X.; FURTADO, J. R.; PINHEIRO, R. R.; ANDRIOLI, A. |
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Afiliação: |
Universidade Estadual do Ceará (UECe) - Fortaleza, CE, Brazil; ANGELA MARIA XAVIER ELOY, CNPC; JOAO RICARDO FURTADO, CNPC; RAYMUNDO RIZALDO PINHEIRO, CNPC; ALICE ANDRIOLI, CNPC. |
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Título: |
Matrix metalloproteinases (MMPs) in buck blood chronically infected by arthritis encephalitis virus in Northeast of Brazil. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
In: INTERNATIONAL CONGRESS ON ANALYTICAL PROTEOMICS, 4., Caparica. Book of abstracts; proceedings. Caparica: Universidade Nova de Lisboa, 2015. Abstract O8A. p. 83. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The objective of this work was to investigate the activity of the MMPs (MMP-2 e MMP-9) in blood serum of chronically infected bucks by CAEV. The experiment was constituted by two groups (n = 5 each group). The first one was composed by five naturally infected bucks (4-5 years) and the second group constituted of five negative bucks (4-5 years) for CAE. Serology was performed using the Western Blotting (WB) and confirmed by Polymerase Chain Reaction (PCR). Blood samples were collected by puncturing the jugular vein from animals and evaluated by zymography (SDS-PAGE) using gelatin as substratum. The gel densitometry analysis showed higher activity (P<0.05) of the pro-MMP-2 and MMP-2 in seropositive group (Fig. 1). The higher activity of the MMPs (MMP-2 and MMP-9) in infected group to CAE suggests a role of these proteases in the chronic inflammatory process in goats, once the key role of MMPs molecules in inflammation are involved in pathophysiological remodeling of the vascular wall, even in animals without apparent disease. |
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Palavras-Chave: |
CAEV; Caprine arthritis encephalit virus; Genômica; Proteases. |
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Thesagro: |
Caprino; Protease. |
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Thesaurus Nal: |
Genomics; Goats. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 01921nam a2200253 a 4500
001 2023960
005 2021-09-06
008 2015 bl uuuu u00u1 u #d
100 1 $aBEZERRA JUNIOR, R. Q.
245 $aMatrix metalloproteinases (MMPs) in buck blood chronically infected by arthritis encephalitis virus in Northeast of Brazil.$h[electronic resource]
260 $aIn: INTERNATIONAL CONGRESS ON ANALYTICAL PROTEOMICS, 4., Caparica. Book of abstracts; proceedings. Caparica: Universidade Nova de Lisboa, 2015. Abstract O8A. p. 83.$c2015
520 $aAbstract: The objective of this work was to investigate the activity of the MMPs (MMP-2 e MMP-9) in blood serum of chronically infected bucks by CAEV. The experiment was constituted by two groups (n = 5 each group). The first one was composed by five naturally infected bucks (4-5 years) and the second group constituted of five negative bucks (4-5 years) for CAE. Serology was performed using the Western Blotting (WB) and confirmed by Polymerase Chain Reaction (PCR). Blood samples were collected by puncturing the jugular vein from animals and evaluated by zymography (SDS-PAGE) using gelatin as substratum. The gel densitometry analysis showed higher activity (P<0.05) of the pro-MMP-2 and MMP-2 in seropositive group (Fig. 1). The higher activity of the MMPs (MMP-2 and MMP-9) in infected group to CAE suggests a role of these proteases in the chronic inflammatory process in goats, once the key role of MMPs molecules in inflammation are involved in pathophysiological remodeling of the vascular wall, even in animals without apparent disease.
650 $aGenomics
650 $aGoats
650 $aCaprino
650 $aProtease
653 $aCAEV
653 $aCaprine arthritis encephalit virus
653 $aGenômica
653 $aProteases
700 1 $aELOY, A. M. X.
700 1 $aFURTADO, J. R.
700 1 $aPINHEIRO, R. R.
700 1 $aANDRIOLI, A.
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