| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
|
Data corrente: |
01/08/1992 |
|
Data da última atualização: |
04/07/2023 |
|
Autoria: |
THOMPSON, J. R.; BEITZ, D. C.; JACOBSON, N. L. |
|
Título: |
Effect of dietary cholesterol and tallow on cholesterol synthesis in the castrated goat. |
|
Ano de publicação: |
1977 |
|
Fonte/Imprenta: |
The Journal of Nutrition, v. 107, n. 9, p. 1632-1639, Sep. 1977. |
|
DOI: |
https://doi.org/10.1093/jn/107.9.1632 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: The effect of dietary cholesterol plus tallow on cholesterol content of several tissues and on in vivo cholesterol biosynthesis was determined in castrated male, mature Saanen goats. The control group consisted of the same type of goats and was fed a dry concentrate mixture. The lipid-supplemented group was fed the same diet plus supplemental cholesterol and tallow at 250 mg and 3 g, respectively, daily per kg body weight for 15 to 18 weeks. Cholesterol content of liver, spleen, and small intestine was increased significantly by cholesterol feeding. Liver, muscle, and skin of control goats contained 47%, 12%, and 20% respectively, of total body cholesterol. In cholesterol plus tallow-fed goats, liver, muscle, and skin contributed 72%, 12%, and 11%, respectively. Adrenal gland and small intestine were the two most active sites for cholesterogenesis (per unit tissue weight), followed in decreasing order by spleen and kidney. Rates in adipose tissue, cerebrum, kidney, skeletal muscle, pancreas, skin, and liver were considerably lower. Cholesterogenesis in whole organs of control goats indicated that most of the sterol was contributed by skin (38%), small intestine (27%), and muscle (21%). After cholesterol plus tallow feeding, marked suppression of cholesterol synthesis occurred in all regions of the small intestine. The cholesterol plus tallow feeding reduced cholesterogenesis in the small intestine, spleen, and kidney to about 25% of that in corresponding tissues of controls; that in adrenal cortex was reduced to 45% of control. Cholesterol plus tallow feeding caused a three-fold increase in cholesterogenesis in adipose tissue. No significant changes occurred in other tissues. MenosAbstract: The effect of dietary cholesterol plus tallow on cholesterol content of several tissues and on in vivo cholesterol biosynthesis was determined in castrated male, mature Saanen goats. The control group consisted of the same type of goats and was fed a dry concentrate mixture. The lipid-supplemented group was fed the same diet plus supplemental cholesterol and tallow at 250 mg and 3 g, respectively, daily per kg body weight for 15 to 18 weeks. Cholesterol content of liver, spleen, and small intestine was increased significantly by cholesterol feeding. Liver, muscle, and skin of control goats contained 47%, 12%, and 20% respectively, of total body cholesterol. In cholesterol plus tallow-fed goats, liver, muscle, and skin contributed 72%, 12%, and 11%, respectively. Adrenal gland and small intestine were the two most active sites for cholesterogenesis (per unit tissue weight), followed in decreasing order by spleen and kidney. Rates in adipose tissue, cerebrum, kidney, skeletal muscle, pancreas, skin, and liver were considerably lower. Cholesterogenesis in whole organs of control goats indicated that most of the sterol was contributed by skin (38%), small intestine (27%), and muscle (21%). After cholesterol plus tallow feeding, marked suppression of cholesterol synthesis occurred in all regions of the small intestine. The cholesterol plus tallow feeding reduced cholesterogenesis in the small intestine, spleen, and kidney to about 25% of that in corresponding tissues of... Mostrar Tudo |
|
Palavras-Chave: |
Cholesterogenesis; Cholesterol biosynthesis; Colesterogene; Dietary cholesterol. |
|
Thesagro: |
Caprino; Nutrição. |
|
Thesaurus Nal: |
Acetates; Adipose tissue; Adrenal cortex; Adrenal glands; Cholesterol; Goats; Ruminant nutrition; Sterols; Tallow. |
|
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 02677naa a2200337 a 4500
001 1519634
005 2023-07-04
008 1977 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1093/jn/107.9.1632$2DOI
100 1 $aTHOMPSON, J. R.
245 $aEffect of dietary cholesterol and tallow on cholesterol synthesis in the castrated goat.$h[electronic resource]
260 $c1977
520 $aAbstract: The effect of dietary cholesterol plus tallow on cholesterol content of several tissues and on in vivo cholesterol biosynthesis was determined in castrated male, mature Saanen goats. The control group consisted of the same type of goats and was fed a dry concentrate mixture. The lipid-supplemented group was fed the same diet plus supplemental cholesterol and tallow at 250 mg and 3 g, respectively, daily per kg body weight for 15 to 18 weeks. Cholesterol content of liver, spleen, and small intestine was increased significantly by cholesterol feeding. Liver, muscle, and skin of control goats contained 47%, 12%, and 20% respectively, of total body cholesterol. In cholesterol plus tallow-fed goats, liver, muscle, and skin contributed 72%, 12%, and 11%, respectively. Adrenal gland and small intestine were the two most active sites for cholesterogenesis (per unit tissue weight), followed in decreasing order by spleen and kidney. Rates in adipose tissue, cerebrum, kidney, skeletal muscle, pancreas, skin, and liver were considerably lower. Cholesterogenesis in whole organs of control goats indicated that most of the sterol was contributed by skin (38%), small intestine (27%), and muscle (21%). After cholesterol plus tallow feeding, marked suppression of cholesterol synthesis occurred in all regions of the small intestine. The cholesterol plus tallow feeding reduced cholesterogenesis in the small intestine, spleen, and kidney to about 25% of that in corresponding tissues of controls; that in adrenal cortex was reduced to 45% of control. Cholesterol plus tallow feeding caused a three-fold increase in cholesterogenesis in adipose tissue. No significant changes occurred in other tissues.
650 $aAcetates
650 $aAdipose tissue
650 $aAdrenal cortex
650 $aAdrenal glands
650 $aCholesterol
650 $aGoats
650 $aRuminant nutrition
650 $aSterols
650 $aTallow
650 $aCaprino
650 $aNutrição
653 $aCholesterogenesis
653 $aCholesterol biosynthesis
653 $aColesterogene
653 $aDietary cholesterol
700 1 $aBEITZ, D. C.
700 1 $aJACOBSON, N. L.
773 $tThe Journal of Nutrition$gv. 107, n. 9, p. 1632-1639, Sep. 1977.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 1 | |
| Registros recuperados : 1 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
