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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
12/02/2010 |
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Data da última atualização: |
05/12/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
OLIVEIRA, L. M. B. de; BEVILAQUA, C. M. L.; COSTA, C. T. C.; MACEDO, I. T. F.; BARROS, R. S.; RODRIGUES, A. C. M.; CAMURÇA-VASCONCELOS, A. L. F.; MORAIS, S. M.; LIMA, Y. C.; VIEIRA, L. da S.; NAVARRO, A. M. C. |
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Afiliação: |
Lorena M. B. de Oliveira, Pós-graduanda Universidade Estadual do Ceará (UECe); Claudia M. L. Bevilaqua, Pós-graduanda UECE; C. T. C. Costa, Pós-graduanda da Universidade Estadual do Ceará (UECE); I.T.F. Macedo, Pós-graduação Universidade Estadual do Ceará (UECe); R.S. Barros, Pós-graduação Universidade Estadual do Ceará (UECe); A.C. M. Rodrigues, Pós-graduação Universidade Estadual do Ceará (UECe); Ana Lourdes Fernandes Camurça-Vasconcelos, Universidade Estadual do Ceará (UECe); S. M. Morais, Pós-graduação da Universidade Estadual do Ceará (Uece); Y. C. Lima, Pós-graduação Universidade Estadual do Ceará (UECe); LUIZ DA SILVA VIEIRA, CNPC; A.M.C. Navarro, Pós-graduação Universidade Estadual do Ceará (UECe). |
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Título: |
Anthelmintic activity of Cocos nucifera L. against sheep gastrointestinal nematodes. |
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Ano de publicação: |
2009 |
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Fonte/Imprenta: |
Veterinary Parasitology, v. 159, n. 1, p. 55-59, 2009. |
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DOI: |
10.1016/j.vetpar.2008.10.018 |
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Idioma: |
Inglês |
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Conteúdo: |
The development of anthelmintic resistance has made the search for alternatives to control gastrointestinal nematodes of small ruminants imperative. Among these alternatives are several medicinal plants traditionally used as anthelmintics. This work evaluated the efficacy of Cocos nucifera fruit on sheep gastrointestinal parasites. The ethyl acetate extract obtained from the liquid of green coconut husk fiber (LGCHF) was submitted to in vitro and in vivo tests. The in vitro assay was based on egg hatching (EHT) and larval development tests (LDT) with Haemonchus contortus. The concentrations tested in the EHT were 0.31, 0.62, 1.25, 2.5 and 5 mg ml1, while in the LDT they were 5, 10, 20, 40 and 80 mg ml1. The in vivo assay was a controlled test. In this experiment, 18 sheep infected with gastrointestinal nematodes were divided into three groups (n = 6), with the following doses administered: G1?400 mg kg1 LGCHF ethyl acetate extract, G2?0.2 mg kg1 moxidectin (Cydectin1) and G3?3% DMSO. The worm burden was analyzed. The results of the in vitro and in vivo tests were submitted to ANOVA and analyzed by the Tukey and Kruskal?Wallis tests, respectively. The extract efficacy in the EHT and LDT, at the highest concentrations tested, was 100% on egg hatching and 99.77% on larval development. The parameters evaluated in the controlled test were not statistically different, showing that despite the significant results of the in vitro tests, the LGCHF ethyl acetate extract showed no activity against sheep gastrointestinal nematodes. MenosThe development of anthelmintic resistance has made the search for alternatives to control gastrointestinal nematodes of small ruminants imperative. Among these alternatives are several medicinal plants traditionally used as anthelmintics. This work evaluated the efficacy of Cocos nucifera fruit on sheep gastrointestinal parasites. The ethyl acetate extract obtained from the liquid of green coconut husk fiber (LGCHF) was submitted to in vitro and in vivo tests. The in vitro assay was based on egg hatching (EHT) and larval development tests (LDT) with Haemonchus contortus. The concentrations tested in the EHT were 0.31, 0.62, 1.25, 2.5 and 5 mg ml1, while in the LDT they were 5, 10, 20, 40 and 80 mg ml1. The in vivo assay was a controlled test. In this experiment, 18 sheep infected with gastrointestinal nematodes were divided into three groups (n = 6), with the following doses administered: G1?400 mg kg1 LGCHF ethyl acetate extract, G2?0.2 mg kg1 moxidectin (Cydectin1) and G3?3% DMSO. The worm burden was analyzed. The results of the in vitro and in vivo tests were submitted to ANOVA and analyzed by the Tukey and Kruskal?Wallis tests, respectively. The extract efficacy in the EHT and LDT, at the highest concentrations tested, was 100% on egg hatching and 99.77% on larval development. The parameters evaluated in the controlled test were not statistically different, showing that despite the significant results of the in vitro tests, the LGCHF ethyl acetate extract showed no acti... Mostrar Tudo |
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Palavras-Chave: |
Brasil; Ceará; Intestinal diseases; LCCV; Líquido da casca de coco; Nematoide gastrintestinal; Parasite Egg Count; Parasito animal; Pequeno ruminante; Proantocianidina; Tanino condensado; Therapeutic use. |
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Thesagro: |
Anti-helmíntico; Cocos Nucifera; Extrato vegetal; Fitoterapia; Haemonchus Contortus; Leite de coco; Ovino; Planta medicinal; Tratamento fitossanitário. |
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Thesaurus Nal: |
Anthelmintics; Brazil; Drug therapy; In vitro studies; Parasitology; Plant extracts; Proanthocyanidins; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03234naa a2200601 a 4500
001 1657838
005 2023-12-05
008 2009 bl uuuu u00u1 u #d
024 7 $a10.1016/j.vetpar.2008.10.018$2DOI
100 1 $aOLIVEIRA, L. M. B. de
245 $aAnthelmintic activity of Cocos nucifera L. against sheep gastrointestinal nematodes.$h[electronic resource]
260 $c2009
520 $aThe development of anthelmintic resistance has made the search for alternatives to control gastrointestinal nematodes of small ruminants imperative. Among these alternatives are several medicinal plants traditionally used as anthelmintics. This work evaluated the efficacy of Cocos nucifera fruit on sheep gastrointestinal parasites. The ethyl acetate extract obtained from the liquid of green coconut husk fiber (LGCHF) was submitted to in vitro and in vivo tests. The in vitro assay was based on egg hatching (EHT) and larval development tests (LDT) with Haemonchus contortus. The concentrations tested in the EHT were 0.31, 0.62, 1.25, 2.5 and 5 mg ml1, while in the LDT they were 5, 10, 20, 40 and 80 mg ml1. The in vivo assay was a controlled test. In this experiment, 18 sheep infected with gastrointestinal nematodes were divided into three groups (n = 6), with the following doses administered: G1?400 mg kg1 LGCHF ethyl acetate extract, G2?0.2 mg kg1 moxidectin (Cydectin1) and G3?3% DMSO. The worm burden was analyzed. The results of the in vitro and in vivo tests were submitted to ANOVA and analyzed by the Tukey and Kruskal?Wallis tests, respectively. The extract efficacy in the EHT and LDT, at the highest concentrations tested, was 100% on egg hatching and 99.77% on larval development. The parameters evaluated in the controlled test were not statistically different, showing that despite the significant results of the in vitro tests, the LGCHF ethyl acetate extract showed no activity against sheep gastrointestinal nematodes.
650 $aAnthelmintics
650 $aBrazil
650 $aDrug therapy
650 $aIn vitro studies
650 $aParasitology
650 $aPlant extracts
650 $aProanthocyanidins
650 $aSheep
650 $aAnti-helmíntico
650 $aCocos Nucifera
650 $aExtrato vegetal
650 $aFitoterapia
650 $aHaemonchus Contortus
650 $aLeite de coco
650 $aOvino
650 $aPlanta medicinal
650 $aTratamento fitossanitário
653 $aBrasil
653 $aCeará
653 $aIntestinal diseases
653 $aLCCV
653 $aLíquido da casca de coco
653 $aNematoide gastrintestinal
653 $aParasite Egg Count
653 $aParasito animal
653 $aPequeno ruminante
653 $aProantocianidina
653 $aTanino condensado
653 $aTherapeutic use
700 1 $aBEVILAQUA, C. M. L.
700 1 $aCOSTA, C. T. C.
700 1 $aMACEDO, I. T. F.
700 1 $aBARROS, R. S.
700 1 $aRODRIGUES, A. C. M.
700 1 $aCAMURÇA-VASCONCELOS, A. L. F.
700 1 $aMORAIS, S. M.
700 1 $aLIMA, Y. C.
700 1 $aVIEIRA, L. da S.
700 1 $aNAVARRO, A. M. C.
773 $tVeterinary Parasitology$gv. 159, n. 1, p. 55-59, 2009.
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Embrapa Caprinos e Ovinos (CNPC) |
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