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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com rosangela.lacerda@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
04/04/2023 |
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Data da última atualização: |
22/08/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ROCHA, R. de F. B.; GARCIA, A. O.; OTTO, P. I.; SILVA, M. V. G. B.; MARTINS, M. F.; MACHADO, M. A.; PANETTO, J. C. do C.; GUIMARÃES, S. E. F. |
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Afiliação: |
RENATA DE FÁTIMA BRETANHA ROCHA, Universidade Federal de Viçosa; ARIELLY OLIVEIRA GARCIA, Universidade Federal de Viçosa; PAMELA ITAJARA OTTO, Universidade Federal de Santa Maria; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARTA FONSECA MARTINS, CNPGL; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; SIMONE ELIZA FACIONI GUIMARÃES, Universidade Federal de Viçosa. |
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Título: |
Runs of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Mammalian Genome, v. 34, p. 482-496, 2023. |
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DOI: |
https://doi.org/10.1007/s00335-023-09989-w |
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Idioma: |
Inglês |
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Conteúdo: |
Runs of homozygosity (ROH) and signatures of selection are the results of selection processes in livestock species that have been shown to afect several traits in cattle. The aim of the current work was to verify the profle of ROH and inbreeding depression in the number of total (TO) and viable oocytes (VO) and the number of embryos (EMBR) in Gir Indicine cattle. In addition, we aim to identify signatures of selection, genes, and enriched regions between Gir subpopulations sorted by breeding value for these traits. The genotype fle contained 2093 animals and 420,718 SNP markers. Breeding values used to sort Gir animals were previously obtained. ROH and signature of selection analyses were performed using PLINK software, followed by ROH-based (FROH) and pedigree-based inbreeding (Fped) and a search for genes and their functions. An average of 50±8.59 ROHs were found per animal. ROHs were separated into classes according to size, ranging from 1 to 2 Mb (ROH1?2Mb: 58.17%), representing ancient inbreeding, ROH2?4Mb (22.74%), ROH4-8Mb (11.34%), ROH8-16Mb (5.51%), and ROH>16Mb (2.24%). Combining our results, we conclude that the increase in general FROH and Fped signifcantly decreases TO and VO; however, in diferent chromosomes traits can increase or decrease with FROH. In the analysis for signatures of selection, we identifed 15 genes from 47 signifcant genomic regions, indicating diferences in populations with high and low breeding value for the three traits. |
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Palavras-Chave: |
Homozigose; Ovócito. |
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Thesagro: |
Bovino; Embrião Animal; Gado Gir. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02311naa a2200277 a 4500 001 2152954 005 2023-08-22 008 2023 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1007/s00335-023-09989-w$2DOI 100 1 $aROCHA, R. de F. B. 245 $aRuns of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle.$h[electronic resource] 260 $c2023 520 $aRuns of homozygosity (ROH) and signatures of selection are the results of selection processes in livestock species that have been shown to afect several traits in cattle. The aim of the current work was to verify the profle of ROH and inbreeding depression in the number of total (TO) and viable oocytes (VO) and the number of embryos (EMBR) in Gir Indicine cattle. In addition, we aim to identify signatures of selection, genes, and enriched regions between Gir subpopulations sorted by breeding value for these traits. The genotype fle contained 2093 animals and 420,718 SNP markers. Breeding values used to sort Gir animals were previously obtained. ROH and signature of selection analyses were performed using PLINK software, followed by ROH-based (FROH) and pedigree-based inbreeding (Fped) and a search for genes and their functions. An average of 50±8.59 ROHs were found per animal. ROHs were separated into classes according to size, ranging from 1 to 2 Mb (ROH1?2Mb: 58.17%), representing ancient inbreeding, ROH2?4Mb (22.74%), ROH4-8Mb (11.34%), ROH8-16Mb (5.51%), and ROH>16Mb (2.24%). Combining our results, we conclude that the increase in general FROH and Fped signifcantly decreases TO and VO; however, in diferent chromosomes traits can increase or decrease with FROH. In the analysis for signatures of selection, we identifed 15 genes from 47 signifcant genomic regions, indicating diferences in populations with high and low breeding value for the three traits. 650 $aBovino 650 $aEmbrião Animal 650 $aGado Gir 653 $aHomozigose 653 $aOvócito 700 1 $aGARCIA, A. O. 700 1 $aOTTO, P. I. 700 1 $aSILVA, M. V. G. B. 700 1 $aMARTINS, M. F. 700 1 $aMACHADO, M. A. 700 1 $aPANETTO, J. C. do C. 700 1 $aGUIMARÃES, S. E. F. 773 $tMammalian Genome$gv. 34, p. 482-496, 2023.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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| Registros recuperados : 6 | |
| 1. |  | MORETZOHN, M.; LEAL BERTIOLI, S.; GUIMARÃES, P.; MADSEN, L.; FREDSLUND, J.; HOUGAARD, B.; SCHAUSER, L.; SANDAL, N.; STOUGAARD, J.; TABATA, S.; BERTIOLI, D. Can legume synteny be useful in guiding the introgression of wild genes into cultivated peanut? Lotus Newletter, v. 37, n. 3, p. 95-96, 2007. Edição do International Workshop Integrating Genomics Into Plant Breeding, Porto Alegre, out. 2007.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 2. |  | MORETZSOHN, M.; LEAL BERTIOLI, S.; GUIMARÃES, P.; MADSEN, L.; FREDSLUND, J.; HOUGAARD, B.; SCHAUSER, L.; SANDAL, N.; STOUGAARD, J.; TABATA, S.; BERTIOLI, D. Can legume synteny be useful in guiding the introgression of wild genes into cultivated peanut? Lotus Newsletter, v. 37, n. 3, p. 95-96, 2007. Edição dos resumos do Workshop, Porto Alegre, RS, 2007.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 3. |  | BERTIOLI, D.; MORETZSOHN, M.; LEAL BERTIOLI, S.; GUIMARÃES, P.; MADSEN, L.; FREDSLUND, J.; HOUGAARD, B.; SCHAUSER, L.; SANDAL, N.; TABATA, S.; STOUGAARD, J. Comparative mapping of Arachis, a basal genus in the Papilionoideae, with the model legumes Lotus japonicus and Medicago truncatula. In: EUROPEAN CONFERENCE ON GRAIN LEGUMES, 6., 2007, Lisbon, Portugal. Integrating legume biology for sustainagle agriculture: book of abstracts. Colney, Norwich: Grain Legumes Integrated Project, 2007. p. 44. Poster 336.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 4. |  | BERTIOLI, D.; SANDAL, N.; MORETZSOHN, M.; MADSEN, L; LEAL BERTIOLI, S.; GUIMARÃES, P.; FREDSLUND, J.; HOUGAARD, B.; SCHAUSER, L.; NIELSEN, A. M.; TABATA, S.; STOUGAARD, J. Comparative mapping of peanut (Arachis hypogaea) with the model legumes Lotus japonicus and Medicago truncatula. In: ANNUAL RESEARCH MEETING, 2007, Benoni, South Africa, Poster Abstracts...Benoni: Generation Challenge Programme - CGIAR, 2007. p. 41.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 5. |  | BERTIOLI, D. J.; MORETZSOHN, M. de C.; MADSEN, L. H.; SANDAL, N.; BERTIOLI, S. C. de M. L.; GUIMARAES, P. M.; HOUGAARD, B. K.; FREDSLUND, J.; SCHAUSER, L.; NIELSEN, A. M.; SATO, S.; TABATA, S.; CANNON, S. B.; STOUGAARD, J. An analysis of synteny of Arachis with Lotus and Medicago sheds new light on the structure, stability and evolution of legume genomes. BMC Genomics, v. 10, n. 45, 2009.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 6. |  | HOUGAARD, B. K.; MADSEN, L. H.; SANDAL, N.; MORETZSOHN, M. de C; FREDSLUND, J.; SCHAUSER, L.; NIELSEN, A. M.; ROHDE, T.; SATO, S.; TABATA, S.; BERTIOLI, D. J.; STOUGAARD, J. Legume anchor markers link syntenic regions between Phaseolus vulgaris, Lotus japonicus, Medicago truncatula and Arachis. Genetics, v. 179, n. 4, p. 2299-2312, 2008.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| Registros recuperados : 6 | |
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