| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Instrumentação. |
|
Data corrente: |
09/06/2025 |
|
Data da última atualização: |
09/06/2025 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
OLIVEIRA, L. F. R.; TEODORO, K. B. R.; ANDRE, R. S.; COSTA, V. P. V.; CAVICCHIOLI, R.; MERCANTE, L. A.; SOUSA, C. P. de; CORREA, D. S. |
|
Afiliação: |
FEDERAL UNIVERSITY OF SÃO CARLOS (UFSCAR); FEDERAL UNIVERSITY OF SÃO CARLOS (UFSCAR); FEDERAL UNIVERSITY OF SÃO CARLOS (UFSCAR); FEDERAL UNIVERSITY OF BAHIA (UFBA); FEDERAL UNIVERSITY OF SÃO CARLOS (UFSCAR); DANIEL SOUZA CORREA, CNPDIA. |
|
Título: |
Combining Electrospun Nanofibers, Paenibacillus polymyxa Fermented Broth, and Silver Nanoparticles for Enhanced Antimicrobial Materials. |
|
Ano de publicação: |
2025 |
|
Fonte/Imprenta: |
BioNanoScience, v. 15, 356, 2025. |
|
Páginas: |
13 p. |
|
DOI: |
https://doi.org/10.1007/s12668-025-01950-2 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract The World Health Organization has identifed antimicrobial resistance as one of the top ten signifcant threats to global public health. For instance, it is predicted that conventional antibiotics will progressively lose their efcacy, accentuating the urgency to fnd innovative solutions to combat microorganisms. Eforts to develop novel antimicrobial agents are highly sought, as well as to explore the potential of natural products, such as plant extracts, and microbial secondary metabolites. In this direction, the Paenibacillus polymyxa RNC-D fermented broth (PFB), which is rich in antimicrobial peptides, was tested as component of nanostructured antimicrobial mat. For this, PFB was incorporated into polycaprolactone (PCL) nanofbers produced by electrospinning, which were further modifed with silver nanoparticles (AgNPs) to produce enhanced antimicrobial materials. The materials were physicochemically characterized using distinct techniques, while the microbiological studies were carried out using the agar disk difusion method, microbial penetration test and percentage of bacterial growth inhibition in suspension. The results showed that the incorporation of 25% of the PFB caused a signifcant improvement in the fber spinnability, resulting in nanofbers with less surface defects. Moreover, the wettability and hydrophilicity of the mats increased. Antimicrobial studies demonstrated the importance of the PFB to the formulation, which acted synergically, improving the distribution of AgNPs onto the fbers. While the fbrous mats demonstrated a protective efect against environmental microbes, when combined with AgNPs the PCL/PFB mats exhibited an inhibition halo of approximately 11.1±0.4 mm in the agar difusion test and showed capability of inhibiting the bacterial growth against E. coli. Therefore, our results demonstrate that combining electrospun nanofbers membrane, fermented broth and silver nanoparticles can be an alternative for developing enhanced antimicrobial materials with potential for biomedical applications. MenosAbstract The World Health Organization has identifed antimicrobial resistance as one of the top ten signifcant threats to global public health. For instance, it is predicted that conventional antibiotics will progressively lose their efcacy, accentuating the urgency to fnd innovative solutions to combat microorganisms. Eforts to develop novel antimicrobial agents are highly sought, as well as to explore the potential of natural products, such as plant extracts, and microbial secondary metabolites. In this direction, the Paenibacillus polymyxa RNC-D fermented broth (PFB), which is rich in antimicrobial peptides, was tested as component of nanostructured antimicrobial mat. For this, PFB was incorporated into polycaprolactone (PCL) nanofbers produced by electrospinning, which were further modifed with silver nanoparticles (AgNPs) to produce enhanced antimicrobial materials. The materials were physicochemically characterized using distinct techniques, while the microbiological studies were carried out using the agar disk difusion method, microbial penetration test and percentage of bacterial growth inhibition in suspension. The results showed that the incorporation of 25% of the PFB caused a signifcant improvement in the fber spinnability, resulting in nanofbers with less surface defects. Moreover, the wettability and hydrophilicity of the mats increased. Antimicrobial studies demonstrated the importance of the PFB to the formulation, which acted synergically, improving the dist... Mostrar Tudo |
|
Palavras-Chave: |
Antimicrobial materials; Electrospinning; Electrospun nanofbers; Fermented broth; Secondary metabolite. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02963naa a2200289 a 4500
001 2176519
005 2025-06-09
008 2025 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/s12668-025-01950-2$2DOI
100 1 $aOLIVEIRA, L. F. R.
245 $aCombining Electrospun Nanofibers, Paenibacillus polymyxa Fermented Broth, and Silver Nanoparticles for Enhanced Antimicrobial Materials.$h[electronic resource]
260 $c2025
300 $a13 p.
520 $aAbstract The World Health Organization has identifed antimicrobial resistance as one of the top ten signifcant threats to global public health. For instance, it is predicted that conventional antibiotics will progressively lose their efcacy, accentuating the urgency to fnd innovative solutions to combat microorganisms. Eforts to develop novel antimicrobial agents are highly sought, as well as to explore the potential of natural products, such as plant extracts, and microbial secondary metabolites. In this direction, the Paenibacillus polymyxa RNC-D fermented broth (PFB), which is rich in antimicrobial peptides, was tested as component of nanostructured antimicrobial mat. For this, PFB was incorporated into polycaprolactone (PCL) nanofbers produced by electrospinning, which were further modifed with silver nanoparticles (AgNPs) to produce enhanced antimicrobial materials. The materials were physicochemically characterized using distinct techniques, while the microbiological studies were carried out using the agar disk difusion method, microbial penetration test and percentage of bacterial growth inhibition in suspension. The results showed that the incorporation of 25% of the PFB caused a signifcant improvement in the fber spinnability, resulting in nanofbers with less surface defects. Moreover, the wettability and hydrophilicity of the mats increased. Antimicrobial studies demonstrated the importance of the PFB to the formulation, which acted synergically, improving the distribution of AgNPs onto the fbers. While the fbrous mats demonstrated a protective efect against environmental microbes, when combined with AgNPs the PCL/PFB mats exhibited an inhibition halo of approximately 11.1±0.4 mm in the agar difusion test and showed capability of inhibiting the bacterial growth against E. coli. Therefore, our results demonstrate that combining electrospun nanofbers membrane, fermented broth and silver nanoparticles can be an alternative for developing enhanced antimicrobial materials with potential for biomedical applications.
653 $aAntimicrobial materials
653 $aElectrospinning
653 $aElectrospun nanofbers
653 $aFermented broth
653 $aSecondary metabolite
700 1 $aTEODORO, K. B. R.
700 1 $aANDRE, R. S.
700 1 $aCOSTA, V. P. V.
700 1 $aCAVICCHIOLI, R.
700 1 $aMERCANTE, L. A.
700 1 $aSOUSA, C. P. de
700 1 $aCORREA, D. S.
773 $tBioNanoScience$gv. 15, 356, 2025.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Instrumentação (CNPDIA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 40 | |
| 4. |  | PORRO, R.; FONSECA, F. L. da; VALENTIM, J. F.; CARLINI, E. L. D. G. Acre. In: PORRO, R. (ed.). Atlas da Bioeconomia inclusiva na Amazônia informações e análises sobre realidades diferenciadas para subsídio a ações em sociobioeconomia. Brasília, DF: Embrapa, 2025. Cap. 2, p. 107-156.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Acre; Embrapa Amazônia Oriental; Embrapa Meio Ambiente. |
|    |
| 5. | | BAYMA, M. M. A.; SA, C. P. de; FONSECA, F. L. da. Avaliação ambiental, social e econômica da recomendação das boas práticas na produção da castanha-do-brasil em florestas naturais do Acre. In: CONGRESSO DA SOCIEDADE BRASILEIRA DE ECONOMIA, ADMINISTRAÇÃO E SOCIOLOGIA RURAL, 51., 2013, Belém, PA. Novas fronteiras da agropecuária no Brasil e na Amazônia: desafios da sustentabilidade. Belém, PA: SOBER, 2013. 10 p.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Acre. |
| |
| 7. | | MARTINS, K.; FONSECA, F. L. da; BENTES, M. P. de M.; COSTA, P. da. Coleta e monitoramento da produção de oleorresina de copaíbas. In: WADT, L. H. de O.; SANTOS, L. M. H.; BENTES, M. P. de M.; OLIVEIRA, V. B. V. (ed.). Produtos florestais não madeireiros: guia metodológico da Rede Kamukaia. Brasília, DF: Embrapa, 2017. p. 119-123.| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Acre; Embrapa Amazônia Oriental; Embrapa Roraima. |
| |
| 10. | | FONSECA, F. L. da; GARCIA, M. F.; RINGENBERG, R.; FORESTI, J.; KOVALESKI, A. Aspectos biológicos de quatro linhagens de Trichogramma pretiosum (RILEY), em ovos de Bonagota cranaodes (MEYRICK). SIMPÓSIO DE CONTROLE BIOLÓGICO, 7., 2001, Poços de Caldas, MG. Anais... Poços de Caldas: Sociedade Entomológica do Brasil, 2001. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Uva e Vinho. |
| |
| 13. | | ARAUJO, H. J. B. de; CORREIA, M. F.; CARDOSO, G. A.; FONSECA, F. L. da. Uso de micro-trator em substituição a animais no sistema de manejo florestal comunitário do PC Peixoto, Acre. In: SIMPÓSIO LATINO-AMERICANO SOBRE MANEJO FLORESTAL, 5., 2011, Santa Maria. Sustentabilidade florestal: [Anais]. Santa Maria: UFSM, Programa de Pós-Graduação em Engenharia Florestal, 2011. p. 51-60.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Acre. |
| |
| 14. | | GARCIA, M. S.; FONSECA, F. L. da; FORESTI, J.; KOVALESKI, A.; RINGENBERG, R. Efeito da idade do hospedeiro no parasitismo de trichogramma pretiosum (RILEY), sobre ovos de Bonagota cranaodes (MEYRICK) (Lepidoptera:tortricidae). SIMPÓSIO DE CONTROLE BIOLÓGICO, 7., 2001, Poços de Caldas, MG. Anais... Poços de Caldas: Sociedade Entomológica do Brasil, 2001. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Uva e Vinho. |
| |
| 16. | | FONSECA, F. L. DA; GARCIA, M. S.; FORESTI, J.; RINGENBERG, R.; KOVALESKI, A. exigências térmicas de Trichogramma pretiosum (RILEY) em ovos de Bonagota cranaodes (MEYRICK) (LEPIDOPTERA:TORTRICIDAE) SIMPÓSIO DE CONTROLE BIOLÓGICO, 7., 2001, Poços de Caldas, MG. Anais... Poços de Caldas: Sociedade Entomológica do Brasil, 2001. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Uva e Vinho. |
| |
| 18. | | KOVALESKI, A.; GARCIA, M. S.; FONSECA, F. L. DA; RINGENBERG, R. Parasitismo de Trichogramma pretiosum (RILEY), sobre ovos de Bonagota cranaodes (MEYRICK), em condições de campo. SIMPÓSIO DE CONTROLE BIOLÓGICO, 7., 2001, Poços de Caldas, MG. Anais... Poços de Caldas: Sociedade Entomológica do Brasil, 2001. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Uva e Vinho. |
| |
| Registros recuperados : 40 | |
|
| Expressão de busca inválida. Verifique!!! |
|
|
