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 | Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
26/11/2015 |
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Data da última atualização: |
20/06/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BONAN, R. F.; BONAN, P. R. F.; BATISTA, A. U. D.; SAMPAIO, F. C.; ALBUQUERQUE, A. J. R.; MORAES, M. C. B.; MATTOSO, L. H. C.; GLENN, G. M.; MEDEIROS, E. S.; OLIVEIRA, J. E. |
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Afiliação: |
ROBERTA F. BONAN, UFPB; PAULO R.F. BONAN, UFPB; ANDRÉ U. D. BATISTA, UFPB; FÁBIO C. SAMPAIO, UFPB; ALLAN J. R. ALBUQUERQUE, UFPB; MARIA CAROLINA BLASSIOLI MORAES, CENARGEN; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA; GREGORY M. GLENN, USDA; ELITON S. MEDEIROS, UFPB; JULIANO E. OLIVEIRA, UFLA. |
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Título: |
In vitro antimicrobial activity of solution blow spun poly(lactic acid)/polyvinylpyrrolidone nanofibers loaded with Copaiba (Copaifera sp.) oil. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Materials Science and Engineering C, v.48, p. 372-377, 2015. |
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DOI: |
10.1016/j.msec.2014.12.021 |
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Idioma: |
Inglês |
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Conteúdo: |
In this study poly(lactic acid) (PLA) and polyvinylpyrrolidone (PVP) micro- and nanofiber mats loaded with Copaiba (Copaifera sp.) oil were produced by solution blow spinning (SBS). The Copaiba (Copaifera sp.) oil was characterized by gas chromatography (GC). Neat PLA and four PLA/PVP blends containing 20% (wt.%) oil were spun and characterized by scanning electron microscopy (SEM) and by studying the surface contact angle, in vitro release rate, and antimicrobial activity. All compositions evaluated were able to produce continuous and smooth fibers by SBS. The addition of PVP increased fiber diameter, and decreased the surface contact angle. GC analysis demonstrated that the main component of the Copaiba oil was ?-caryophyllene, a known antimicrobial agent. In vitro release tests of Copaiba oil volatiles demonstrated a higher release rate in fibers containing PVP. Fiber mats made from blends containing higher amounts of PVP had greater antimicrobial action against Staphylococcus aureus. The results confirm the potential of the fiber mats for use in controlled drug release and could lead to promising applications in the biomedical field. |
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Palavras-Chave: |
Antimicrobial activity; Atividade antimicrobiana; Copaifera sp oil; Drug delivery system; Nanofibras. |
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Thesaurus Nal: |
nanofibers. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02152naa a2200313 a 4500
001 2029744
005 2024-06-20
008 2015 bl uuuu u00u1 u #d
024 7 $a10.1016/j.msec.2014.12.021$2DOI
100 1 $aBONAN, R. F.
245 $aIn vitro antimicrobial activity of solution blow spun poly(lactic acid)/polyvinylpyrrolidone nanofibers loaded with Copaiba (Copaifera sp.) oil.$h[electronic resource]
260 $c2015
520 $aIn this study poly(lactic acid) (PLA) and polyvinylpyrrolidone (PVP) micro- and nanofiber mats loaded with Copaiba (Copaifera sp.) oil were produced by solution blow spinning (SBS). The Copaiba (Copaifera sp.) oil was characterized by gas chromatography (GC). Neat PLA and four PLA/PVP blends containing 20% (wt.%) oil were spun and characterized by scanning electron microscopy (SEM) and by studying the surface contact angle, in vitro release rate, and antimicrobial activity. All compositions evaluated were able to produce continuous and smooth fibers by SBS. The addition of PVP increased fiber diameter, and decreased the surface contact angle. GC analysis demonstrated that the main component of the Copaiba oil was ?-caryophyllene, a known antimicrobial agent. In vitro release tests of Copaiba oil volatiles demonstrated a higher release rate in fibers containing PVP. Fiber mats made from blends containing higher amounts of PVP had greater antimicrobial action against Staphylococcus aureus. The results confirm the potential of the fiber mats for use in controlled drug release and could lead to promising applications in the biomedical field.
650 $ananofibers
653 $aAntimicrobial activity
653 $aAtividade antimicrobiana
653 $aCopaifera sp oil
653 $aDrug delivery system
653 $aNanofibras
700 1 $aBONAN, P. R. F.
700 1 $aBATISTA, A. U. D.
700 1 $aSAMPAIO, F. C.
700 1 $aALBUQUERQUE, A. J. R.
700 1 $aMORAES, M. C. B.
700 1 $aMATTOSO, L. H. C.
700 1 $aGLENN, G. M.
700 1 $aMEDEIROS, E. S.
700 1 $aOLIVEIRA, J. E.
773 $tMaterials Science and Engineering C$gv.48, p. 372-377, 2015.
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| 6. |  | AGUIAR, J. T. de; D'AFONSECA, D. S.; SILVA, S. C. da; HEINEMANN, A. B.; LOBO JUNIOR, M. Validação de dados obtidos via satélite para estimativa de variáveis climatológicas em diferentes regiões brasileiras. In: SEMINÁRIO JOVENS TALENTOS, 8., 2014, Santo Antônio de Goiás. Coletânea dos resumos apresentados. Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2014. p. 34. (Embrapa Arroz e Feijão. Documentos, 306).| Tipo: Resumo em Anais de Congresso |
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