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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
16/10/2015 |
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Data da última atualização: |
02/02/2016 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FORNARI, M. B.; ZANELLA, R.; IBELLI, A. M. G.; FERNANDES, L. T.; CANTAO, M. E.; SOCCOL, V. T.; LEDUR, M. C.; PEIXOTO, J. de O. |
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Afiliação: |
MARCELO BATISTA FORNARI, UFPR; RICARDO ZANELLA, CNPq; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; LANA TEIXEIRA FERNANDES; MAURICIO EGIDIO CANTAO, CNPSA; VANETE THOMAZ SOCCOL, UFPR; MONICA CORREA LEDUR, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA. |
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Título: |
Unraveling the associations of osteoprotegerin gene with production traits in a paternal broiler line. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
SpringerPlus, v. 3, n. 682, 2014. |
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DOI: |
10.1186/2193-1801-3-682 |
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Idioma: |
Inglês |
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Conteúdo: |
Improvements on growth and carcass traits in the poultry industry have been achieved by intense selection for heavier chickens at early ages. This faster growth has caused serious problems due to insufficient skeletal structure development needed to support the musculature of modern broilers. The osteoprotegerin gene (OPG), located on GGA2, is an important regulator of bone metabolism and reabsorption, being suggestive as a possible functional candidate gene associated with bone integrity in chickens. This study reports associations of a single nucleotide polymorphism (SNP) in the OPG gene with production traits in a parental broiler line. Different phenotypic groups were evaluated: performance, carcass and skeletal traits. SNPs were identified within the OPG gene and the most informative SNP g.9144C > G was chosen for association analyses. Chickens (n = 1230) were genotyped using PCR-RFLP. The association was carried out with QxPaK v4.0 software using a mixed model including sex, hatch and SNP as fixed effects, and the infinitesimal and residual as random effects. The OPG SNP was associated with important traits as body weight at 21 days, weights of tibia and drumstick skin, leg muscle yield, and tibia breaking strength (P < 0.05). Associations were explained by the additive effect of the SNP and the additive effect within sex. This SNP could be considered a potential marker to improve bone resistance in chickens; however, caution should be taken because of its negative effect in other important traits evaluated in this study. Furthermore, these findings suggest a possible involvement of the OPG gene in fat deposition in poultry. MenosImprovements on growth and carcass traits in the poultry industry have been achieved by intense selection for heavier chickens at early ages. This faster growth has caused serious problems due to insufficient skeletal structure development needed to support the musculature of modern broilers. The osteoprotegerin gene (OPG), located on GGA2, is an important regulator of bone metabolism and reabsorption, being suggestive as a possible functional candidate gene associated with bone integrity in chickens. This study reports associations of a single nucleotide polymorphism (SNP) in the OPG gene with production traits in a parental broiler line. Different phenotypic groups were evaluated: performance, carcass and skeletal traits. SNPs were identified within the OPG gene and the most informative SNP g.9144C > G was chosen for association analyses. Chickens (n = 1230) were genotyped using PCR-RFLP. The association was carried out with QxPaK v4.0 software using a mixed model including sex, hatch and SNP as fixed effects, and the infinitesimal and residual as random effects. The OPG SNP was associated with important traits as body weight at 21 days, weights of tibia and drumstick skin, leg muscle yield, and tibia breaking strength (P < 0.05). Associations were explained by the additive effect of the SNP and the additive effect within sex. This SNP could be considered a potential marker to improve bone resistance in chickens; however, caution should be taken because of its negative eff... Mostrar Tudo |
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Palavras-Chave: |
Bone resistance; Fat deposition; TNFRSF11B. |
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Thesagro: |
Frango de corte; Melhoramento genético animal; Osso. |
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Thesaurus Nal: |
Bone metabolism; Broiler chickens; Chickens; Genetic markers; Single nucleotide polymorphism. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02664naa a2200349 a 4500
001 2026619
005 2016-02-02
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1186/2193-1801-3-682$2DOI
100 1 $aFORNARI, M. B.
245 $aUnraveling the associations of osteoprotegerin gene with production traits in a paternal broiler line.$h[electronic resource]
260 $c2014
520 $aImprovements on growth and carcass traits in the poultry industry have been achieved by intense selection for heavier chickens at early ages. This faster growth has caused serious problems due to insufficient skeletal structure development needed to support the musculature of modern broilers. The osteoprotegerin gene (OPG), located on GGA2, is an important regulator of bone metabolism and reabsorption, being suggestive as a possible functional candidate gene associated with bone integrity in chickens. This study reports associations of a single nucleotide polymorphism (SNP) in the OPG gene with production traits in a parental broiler line. Different phenotypic groups were evaluated: performance, carcass and skeletal traits. SNPs were identified within the OPG gene and the most informative SNP g.9144C > G was chosen for association analyses. Chickens (n = 1230) were genotyped using PCR-RFLP. The association was carried out with QxPaK v4.0 software using a mixed model including sex, hatch and SNP as fixed effects, and the infinitesimal and residual as random effects. The OPG SNP was associated with important traits as body weight at 21 days, weights of tibia and drumstick skin, leg muscle yield, and tibia breaking strength (P < 0.05). Associations were explained by the additive effect of the SNP and the additive effect within sex. This SNP could be considered a potential marker to improve bone resistance in chickens; however, caution should be taken because of its negative effect in other important traits evaluated in this study. Furthermore, these findings suggest a possible involvement of the OPG gene in fat deposition in poultry.
650 $aBone metabolism
650 $aBroiler chickens
650 $aChickens
650 $aGenetic markers
650 $aSingle nucleotide polymorphism
650 $aFrango de corte
650 $aMelhoramento genético animal
650 $aOsso
653 $aBone resistance
653 $aFat deposition
653 $aTNFRSF11B
700 1 $aZANELLA, R.
700 1 $aIBELLI, A. M. G.
700 1 $aFERNANDES, L. T.
700 1 $aCANTAO, M. E.
700 1 $aSOCCOL, V. T.
700 1 $aLEDUR, M. C.
700 1 $aPEIXOTO, J. de O.
773 $tSpringerPlus$gv. 3, n. 682, 2014.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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| Registros recuperados : 90 | |
| 4. |  | SANTOS, A. F. dos; MATSUOKA, K.; ALFENAS, A. C. Importância da estrutura da superfície foliolar da seringueira na interação Phytophthora - Hevea. In: CONGRESSO BRASILEIRO DE FITOPATOLOGIA, 24., 1991, Rio de Janeiro. Resumos... Fitopatologia Brasileira, v. 16, n. 2, p. L, jun. 1991.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 5. | | NOBREGA, M. B. de M.; ALFENAS, A. C.; PETERS, I.; CHITARRA, G. S. Análise de isoenzimas em doze espécies de Eucalyptus. In: CONGRESSO NACIONAL DE GENÉTICA, 41., 1995, Caxambu. Programa e resumos. Revista Brasileira de Genética, v. 18, n. 3, p. 251, set. 1995. Suplemento.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 8. | | JUNQUEIRA, N. T. V.; CHAVES, G. M.; ZAMBOLIM, L.; ALFENAS, A. C.; GASPAROTTO, L. Efeito do número de repicagens, idade da cultura armazenada e luminosidade sobre a esporulação e patogenicidade de Microcyclus ulei, agente etiológico do Mal das Folhas da seringueira. Fitopatologia Brasileira, v. 9, n. 2, p. 328, jun. 1984. Suplemento. Edição dos resumos do17º Congresso da Sociedade Brasileira de Fitopatologia, 1984. Resumo 028.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 10. | | ALFENAS, A. C.; GUIMARÃES, L. M. da S.; RESENDE, M. D. V. de. Genetic basis of resistance in Eucalyptus spp. pathosystems. In: INTERNATIONAL WORKSHOP ON GENETICS OF HOST-PARASITE INTERACTIONS IN FORESTRY, 4., 2011, Eugene. Proceedings... Albany: USDA - Forest Service, 2012. Coordenadores técnicos: Richard A. Sniezko, Alvin D. Yanchuk, John T. Kliejunas, Katharine M. Palmieri, Janice M. Alexander, Susan J. Frankel.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Florestas. |
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| 13. | | REIS, A.; MAFIA, R. G.; SILVA, P. P.; LOPES, C. A.; ALFENAS, A. C. Cylindrocladium spathiphylli, causal agent of spathiphyllum root and collar rot in the Federal District-Brazil. Fitopatologia Brasileira, Brasília, v. 29, n. 1, p. 102, fev. 2004.| Biblioteca(s): Embrapa Hortaliças. |
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| 16. | | CUNHA, J. de F.; PICOLI, E. A. de T.; ALFENAS, A. C.; GONCALVES, R. C. Efeito "in vitro" de antibióticos e rizobactérias no controle de bactérias fitopatogênicas ao Eucalyptus spp. Revista Árvore, Viçosa, MG, v. 30, n. 6, p. 871-876, 2006.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Nacional - B |
| Biblioteca(s): Embrapa Acre. |
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| 17. | | NOBREGA, M. B. de M.; PETERS, I.; ALFENAS, A. C.; CHITARRA, G. S. Identificação de locos e alelos isoenzimáticos em 12 espécies de Eucalyptus. In: CONGRESSO NACIONAL DE GENÉTICA, 41., 1995, Caxambu. Programa e resumos. Revista Brasileira de Genética, v. 18, n. 3, p. 252, set. 1995. Suplemento. Resumo A.330.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 19. | | SANTOS, A. F. dos; MATSUOKA, K.; ALFENAS, A. C.; MAFFIA, L. A. Identificação de Phytophthora em seringueira (Hevea spp.) no Estado da Bahia. In: CONGRESSO BRASILEIRO DE FITOPATOLOGIA, 24., 1991, Rio de Janeiro. Resumos... Fitopatologia Brasileira, v. 16, n. 2, p. LV, jun. 1991.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| Registros recuperados : 90 | |
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