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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite; Embrapa Rondônia. |
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Data corrente: |
23/02/2018 |
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Data da última atualização: |
27/01/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SILVA, M. R.; PEREIRA, J. C.; COSTA, R. R.; DIAS, J. A.; GUIMARÃES, M. D. C.; LEITE, I. C. G. |
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Afiliação: |
MARCIO ROBERTO SILVA, CNPGL; J. C. Pereira, UFJF; R. R. Costa, UFJF; J. A. Dias, Embrapa Rondônia; M. D. C. Guimarães, UFMG; I. C. G. Leite, UFJF. |
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Título: |
Drug addiction and alcoholism as predictors for tuberculosis treatment default in Brazil: a prospective cohort study. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Epidemiology & infection, v. 145. n. 16, p. 3516-3524, 2017. |
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Idioma: |
Inglês |
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Conteúdo: |
SUMMARY This study aimed to evaluate the risk factors for tuberculosis (TB) treatment default in a priority city for disease control in Brazil. A cohort of TB cases diagnosed from 2008 to 2009 was followed up from patients? entry into three outpatient sites, in Juiz de Fora, Minas Gerais (Brazil), until the recording of the outcomes. Drug addiction, alcoholism and treatment site appeared to be independently associated with default. Current users of crack as the hardest drug (odds ratio (OR) 12·25, 95% confidence interval (CI) 3·04?49·26) were more likely to default than other hard drug users (OR 5·67, 95% CI 1·34?24·03), former users (OR 4·12, 95% CI 1·11?15·20) and those not known to use drugs (reference group). Consumers at high risk of alcoholism (OR 2·94, 95% CI 1·08?7·99) and those treated in an outpatient hospital unit (OR 8·22, 95% CI 2·79?24·21%) also were more likely to default. Our results establish that substance abuse was independently associated with default. National TB programmes might be more likely to achieve their control targets if they include interventions aimed at improving adherence and cure rates, by diagnosing and treating substance abuse concurrently with standard TB therapy. |
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Palavras-Chave: |
Alcoholism; Treatment default. |
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Thesaurus Nal: |
risk factors; substance abuse; tuberculosis. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01966naa a2200241 a 4500
001 2088076
005 2023-01-27
008 2017 bl uuuu u00u1 u #d
100 1 $aSILVA, M. R.
245 $aDrug addiction and alcoholism as predictors for tuberculosis treatment default in Brazil$ba prospective cohort study.$h[electronic resource]
260 $c2017
520 $aSUMMARY This study aimed to evaluate the risk factors for tuberculosis (TB) treatment default in a priority city for disease control in Brazil. A cohort of TB cases diagnosed from 2008 to 2009 was followed up from patients? entry into three outpatient sites, in Juiz de Fora, Minas Gerais (Brazil), until the recording of the outcomes. Drug addiction, alcoholism and treatment site appeared to be independently associated with default. Current users of crack as the hardest drug (odds ratio (OR) 12·25, 95% confidence interval (CI) 3·04?49·26) were more likely to default than other hard drug users (OR 5·67, 95% CI 1·34?24·03), former users (OR 4·12, 95% CI 1·11?15·20) and those not known to use drugs (reference group). Consumers at high risk of alcoholism (OR 2·94, 95% CI 1·08?7·99) and those treated in an outpatient hospital unit (OR 8·22, 95% CI 2·79?24·21%) also were more likely to default. Our results establish that substance abuse was independently associated with default. National TB programmes might be more likely to achieve their control targets if they include interventions aimed at improving adherence and cure rates, by diagnosing and treating substance abuse concurrently with standard TB therapy.
650 $arisk factors
650 $asubstance abuse
650 $atuberculosis
653 $aAlcoholism
653 $aTreatment default
700 1 $aPEREIRA, J. C.
700 1 $aCOSTA, R. R.
700 1 $aDIAS, J. A.
700 1 $aGUIMARÃES, M. D. C.
700 1 $aLEITE, I. C. G.
773 $tEpidemiology & infection$gv. 145. n. 16, p. 3516-3524, 2017.
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