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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Corte. |
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Data corrente: |
05/05/2021 |
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Data da última atualização: |
25/05/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MIRABALLES, C.; BARROS, A. T. M. de; LUCAS, M.; KLAFKE, G. M.; DOMINGUES, L. N.; RIET-CORREA. |
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Afiliação: |
CECILIA MIRABALLES, Instituto Nacional de Investigación Agropecuaria (INIA), Plataforma de Salud Animal, Estación Experimental INIA Tacuarembó, Ruta 50 Km 11, Colonia, 39173, Uruguay.; ANTONIO THADEU MEDEIROS DE BARROS, CNPGC; MARTIN LUCAS, Instituto Nacional de Investigación Agropecuaria (INIA), Plataforma de Salud Animal, Estación Experimental INIA Tacuarembó, Ruta 50 Km 11, Colonia, 39173, Uruguay.; GUILHERME M. KLAFKE, Centro de Pesquisa em Saúde Animal, Instituto de Pesquisas Veterinárias, Eldorado do Sul.; LUÍSA N. DOMINGUES, USDA-ARS Knipling-Bushland U.S. Livestock Insects Research Laboratory, 2700 Fredericksburg Road, Kerrville, TX, USA 78028.; FRANKLIN RIET-CORREA, Graduate Program in Animal Science in the Tropics, Escola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia (UFBA). |
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Título: |
Susceptibility of field populations of Haematobia irritans to fipronil in Uruguay. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, n. 41:e06821, 2021 |
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Idioma: |
Inglês |
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Palavras-Chave: |
Hematobia irritans. |
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Thesaurus Nal: |
Bioassays; Fipronil; Integrated pest management. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/223078/1/Miraballes-et-al-2021-Susceptibility-GC.pdf
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Marc: |
LEADER 00647naa a2200217 a 4500
001 2131698
005 2021-05-25
008 2021 bl uuuu u00u1 u #d
100 1 $aMIRABALLES, C.
245 $aSusceptibility of field populations of Haematobia irritans to fipronil in Uruguay.$h[electronic resource]
260 $c2021
650 $aBioassays
650 $aFipronil
650 $aIntegrated pest management
653 $aHematobia irritans
700 1 $aBARROS, A. T. M. de
700 1 $aLUCAS, M.
700 1 $aKLAFKE, G. M.
700 1 $aDOMINGUES, L. N.
700 1 $aRIET-CORREA
773 $tPesquisa Veterinária Brasileira$gn. 41:e06821, 2021
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Registro original: |
Embrapa Gado de Corte (CNPGC) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
28/08/2007 |
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Data da última atualização: |
17/01/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
Internacional - A |
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Autoria: |
SIMÕES, M.; BAHIA, D.; ZERLOTINI, A.; TORRES, K.; ARTIGUENAVE, F.; NESHICH, G.; KUSER, P.; OLIVEIRA, G. |
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Afiliação: |
MARIANA SIMÕES, Fiocruz; DIANA BAHIA, Fiocruz; ADHEMAR ZERLOTINI, Fiocruz; KLEIDER TORRES, Fiocruz; FRANÇOIS ARTIGUENAVE, Inra; GORAN NESHICH, CNPTIA; PAULA REGINA KUSER FALCAO, CNPTIA; GUILHERME OLIVEIRA, Fiocruz, Santa Casa de Belo Horizonte. |
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Título: |
Single nucleotide polymorphisms identification in expressed genes of Schistosoma mansoni. |
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Ano de publicação: |
2007 |
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Fonte/Imprenta: |
Molecular and Biochemical Parasitology, v. 154, p. 134-140, 2007. |
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DOI: |
10.1016/j.molbiopara.2007.04.003 |
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Idioma: |
Inglês |
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Conteúdo: |
Single nucleotide polymorphism (SNP) markers have been shown to be useful in genetic investigations of medically important parasites and their hosts. In this paper, we describe the prediction and validation of SNPs in ESTs of Schistosoma mansoni. We used 107,417 public sequences of S. mansoni and identified 15,614 high-quality candidate SNPs in 12,184 contigs. The presence of predicted SNPs was observed in well characterized antigens and vaccine candidates such as those coding for myosin; Sm14 and Sm23; cathepsin B and triosephosphate isomerase (TPI). Additionally, SNPs were experimentally validated for the cathepsin B. A comparative model of the S. mansoni cathepsin B was built for predicting the possible consequences of amino acid substitutions on the protein structure. An analysis of the substitutions indicated that the amino acids were mostly located on the surface of the molecule, and we found no evidence for a significant conformational change of the enzyme. However, at least one of the substitutions could result in a structural modification of an epitope |
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Palavras-Chave: |
Bioinformática; Comparative modeling; Computational biology; Polimorfismo de nucleotídeo único. |
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Thesagro: |
Schistosoma Mansoni. |
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Thesaurus NAL: |
Bioinformatics; Cathepsin B; Models; Single nucleotide polymorphism. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02052naa a2200325 a 4500
001 1002699
005 2020-01-17
008 2007 bl uuuu u00u1 u #d
024 7 $a10.1016/j.molbiopara.2007.04.003$2DOI
100 1 $aSIMÕES, M.
245 $aSingle nucleotide polymorphisms identification in expressed genes of Schistosoma mansoni.$h[electronic resource]
260 $c2007
520 $aSingle nucleotide polymorphism (SNP) markers have been shown to be useful in genetic investigations of medically important parasites and their hosts. In this paper, we describe the prediction and validation of SNPs in ESTs of Schistosoma mansoni. We used 107,417 public sequences of S. mansoni and identified 15,614 high-quality candidate SNPs in 12,184 contigs. The presence of predicted SNPs was observed in well characterized antigens and vaccine candidates such as those coding for myosin; Sm14 and Sm23; cathepsin B and triosephosphate isomerase (TPI). Additionally, SNPs were experimentally validated for the cathepsin B. A comparative model of the S. mansoni cathepsin B was built for predicting the possible consequences of amino acid substitutions on the protein structure. An analysis of the substitutions indicated that the amino acids were mostly located on the surface of the molecule, and we found no evidence for a significant conformational change of the enzyme. However, at least one of the substitutions could result in a structural modification of an epitope
650 $aBioinformatics
650 $aCathepsin B
650 $aModels
650 $aSingle nucleotide polymorphism
650 $aSchistosoma Mansoni
653 $aBioinformática
653 $aComparative modeling
653 $aComputational biology
653 $aPolimorfismo de nucleotídeo único
700 1 $aBAHIA, D.
700 1 $aZERLOTINI, A.
700 1 $aTORRES, K.
700 1 $aARTIGUENAVE, F.
700 1 $aNESHICH, G.
700 1 $aKUSER, P.
700 1 $aOLIVEIRA, G.
773 $tMolecular and Biochemical Parasitology$gv. 154, p. 134-140, 2007.
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Embrapa Agricultura Digital (CNPTIA) |
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