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| Registros recuperados : 10 | |
| 2. |  | CAZÉ, A. L. R.; HOFFMANN, L. V.; SILVA, M. G.; GIBAND, M.; BARROSO, P. A. V. Avaliação molecular de hibridização entre genótipos susceptíveis e resistentes à doença do azul do algodoeiro. In.: WORKSHOP INTERNACIONAL EM BIOTECNOLOGIA, 1.; ENCONTRO ALFA-VALNATURA, 3.; JORNADA CIENTÍFICA DO LIKA, 3., 2008, Recife. Resumos...Recife: Ed. Universitária da UFPE, 2008. p. 375-376| Biblioteca(s): Embrapa Algodão. |
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| 3. | | OLIVEIRA, T. S.; HOFFMANN, L. V.; CAZÉ, A. L. R.; BARROSO, P. A. V.; GIBAND, M. Validação de metodologias associadas a reação de PCR para detecção de microssatélites para mapeamento molecular da doença azul do algodoeiro. In.: ENCONTRO DE PRODUÇÃO CIENTÍFICA DA EMBRAPA ALGODÃO - EPC 2008, 3., 2008, Campina Grande. Resumos...Campina Grande: Embrapa Algodão, 2008. p. 34 (Embrapa Algodão. Documentos, 213).| Biblioteca(s): Embrapa Algodão. |
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| 4. | | CAZÉ, A. L. R.; LUCENA, V. S.; MENEZES, I. P. P. de; BARROSO, P. A. V.; RIBEIRO, J. L. Avaliação qualitativa in situ dos acessos de algodoeiros coletados no Estado do Maranhão. In: CONGRESSO NACIONAL DE BOTÂNICA, 59.; REUNIÃO NORDESTINA DE BOTÂNICA, 31.; CONGRESSO LATINOAMERICANO Y DEL CARIBE DE CACTÁCEAS Y OTRAS SUCULENTAS, 4.; CONGRESS OF INTERNATIONAL ORGANIZATION FOR SUCULENT PLANT STUDY, 30., 2008, Natal. Atualidades, desafios e perspectivas da botânica no Brasil: resumos. Natal: UFERSA: UFRN: SBB, 2008. p. 221| Biblioteca(s): Embrapa Meio-Norte. |
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| 5. | | CAZÉ, A. L. R.; LUCENA, V. S.; MENEZES, I. P. P. de; BARROSO, P. A. V.; RIBEIRO, J. L. Avaliação qualitativa in situ dos acessos de algodoeiros coletados no Estado do Maranhão. In: CONGRESSO NACIONAL DE BOTÂNICA, 59.; REUNIÃO NORDESTINA DE BOTÂNICA, 31.; CONGRESSO LATINOAMERICANO Y DEL CARIBE DE CACTÁCEAS Y OTRAS SUCULENTAS, 4.; CONGRESS OF INTERNATIONAL ORGANIZATION FOR SUCULENT PLANT STUDY, 30., 2008, Natal. Atualidades, desafios e perspectivas da botânica no Brasil: resumos. Natal: UFERSA: UFRN: SBB, 2008.| Biblioteca(s): Embrapa Algodão. |
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| 6. | | CAZÉ, A. L. R.; LUCENA, V. S.; MENEZES, I. P. P. de; HOFFMANN, L. V.; RIBEIRO, J. L. Caracterização in situ de populações de Gossypium hirsutum L. e G. barbadense L. (Malvaceae) do Estado do Piauí. In: CONGRESSO NACIONAL DE BOTÂNICA, 59.; REUNIÃO NORDESTINA DE BOTÂNICA, 31.; CONGRESO LATINOAMERICANO Y DEL CARIBE DE CACTÁCEAS Y OTRAS SUCULENTAS, 4.; CONGRESS OF INTERNATIONAL ORGANIZATION FOR SUCULENT PLANT STUDY, 30., 2008, Natal. Atualidades, desafios e perspectivas da botânica no Brasil: resumos. Natal: UFERSA: UFRN: SBB, 2008. p. 268| Biblioteca(s): Embrapa Meio-Norte. |
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| 8. | | SILVA, M. G.; CAZÉ, A. L. R.; PEREIRA, G. S.; ALMEIDA, V. C.; SILVA FILHO, J. L.; BARROSO, P. A. V.; HOFFMANN, L. V. Distância genética entre linhagens-elite de algodoeiro herbáceo com base em marcadores microssatélites. In: CONGRESSO BRASILEIRO DE GENÉTICA, 54., 2008, Salvador. Resumos... Salvador: SBG, 2008.| Biblioteca(s): Embrapa Algodão. |
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| 9. | | PEREIRA, G. da S.; CAZÉ, A. L. R.; SILVA, M. G. da; ALMEIDA, V. C.; MAGALHAES, F. O. da C.; SILVA FILHO, J. L. da; BARROSO, P. A. V.; HOFFMANN, L. V. Optimal use of SSR markers for varietal identification of upland cotton. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 50, n. 7, p. 571-581, jul. 2015. Título em português: Uso otimizado de marcadores SSR para identificação varietal de algodoeiro herbáceo.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 10. | | PEREIRA, G. DA S.; CAZÉ, A. L. R.; SILVA, M. G. DA; ALMEIDA, V. C.; MAGALHAES, F. O. da C.; SILVA FILHO, J. L. da; BARROSO, P. A. V.; HOFFMANN, L. V. Uso otimizado de marcadores SSR para identificação varietal de algodoeiro herbáceo. Pesquisa Agropecuária Brasileira, Brasíla, DF, v. 50, n. 7, p. 571-581, jul. 2015.| Biblioteca(s): Embrapa Algodão. |
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| Registros recuperados : 10 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
15/12/2022 |
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Data da última atualização: |
01/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
BARRETO, P.; DAMBIRE, C.; SHARMA, G.; VICENTE, J.; OSBORNE, R.; YASSITEPE, J. E. de C. T.; GIBBS, D. J.; MAIA, I. G.; HOLDSWORTH, M. J.; ARRUDA, P. |
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Afiliação: |
PEDRO BARRETO, UNIVERSIDADE ESTADUAL PAULISTA; CHARLENE DAMBIRE, UNIVERSITY OF NOTTINGHAM; GUNJAN SHARMA, UNIVERSITY OF NOTTINGHAM; JORGE VICENTE, UNIVERSITY OF NOTTINGHAM; RORY OSBORNE, UNIVERSITY OF BIRMINGHAM; JULIANA ERIKA DE C T YASSITEPE, CNPTIA; DANIEL J. GIBBS, UNIVERSITY OF BIRMINGHAM; IVAN G. MAIA, UNIVERSIDADE ESTADUAL PAULISTA; MICHAEL J. HOLDSWORTH, UNIVERSITY OF NOTTINGHAM; PAULO ARRUDA, UNIVERSIDADE ESTADUAL DE CAMPINAS. |
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Título: |
Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Current Biology, v. 32, n. 6, p. 1403-1411, Mar. 2022. |
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DOI: |
https://doi.org/10.1016/j.cub.2022.01.037 |
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Idioma: |
Inglês |
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Notas: |
Short communication. Na publicação: Juliana Yassitepe. |
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Conteúdo: |
SUMMARY. Mitochondrial retrograde signaling is an important component of intracellular stress signaling in eukaryotes. UNCOUPLING PROTEIN (UCP)1 is an abundant plant inner-mitochondrial membrane protein with multiple functions including uncoupled respiration and amino-acid transport1,2 that influences broad abiotic stress responses. Although the mechanism(s) through which this retrograde function acts is unknown, overexpression of UCP1 activates expression of hypoxia (low oxygen)-associated nuclear genes.3,4 Here we show in Arabidopsis thaliana that UCP1 influences nuclear gene expression and physiological response by inhibiting the cytoplasmic PLANT CYSTEINE OXIDASE (PCO) branch of the PROTEOLYSIS (PRT)6 N-degron pathway, a major mechanism of oxygen and nitric oxide (NO) sensing.5 Overexpression of UCP1 (UCP1ox) resulted in the stabilization of an artificial PCO N-degron pathway substrate, and stability of this reporter protein was influenced by pharmacological interventions that control UCP1 activity. Hypoxia and salt-tolerant phenotypes observed in UCP1ox lines resembled those observed for the PRT6 N-recognin E3 ligase mutant prt6-1. Genetic analysis showed that UCP1 regulation of hypoxia responses required the activity of PCO N-degron pathway ETHYLENE RESPONSE FACTOR (ERF)VII substrates. Transcript expression analysis indicated that UCP1 regulation of hypoxia-related gene expression is a normal component of seedling development. Our results show that mitochondrial retrograde signaling represses the PCO N-degron pathway, enhancing substrate function, thus facilitating downstream stress responses. This work reveals a novel mechanism through which mitochondrial retrograde signaling influences nuclear response to hypoxia by inhibition of an ancient cytoplasmic pathway of eukaryotic oxygen sensing. MenosSUMMARY. Mitochondrial retrograde signaling is an important component of intracellular stress signaling in eukaryotes. UNCOUPLING PROTEIN (UCP)1 is an abundant plant inner-mitochondrial membrane protein with multiple functions including uncoupled respiration and amino-acid transport1,2 that influences broad abiotic stress responses. Although the mechanism(s) through which this retrograde function acts is unknown, overexpression of UCP1 activates expression of hypoxia (low oxygen)-associated nuclear genes.3,4 Here we show in Arabidopsis thaliana that UCP1 influences nuclear gene expression and physiological response by inhibiting the cytoplasmic PLANT CYSTEINE OXIDASE (PCO) branch of the PROTEOLYSIS (PRT)6 N-degron pathway, a major mechanism of oxygen and nitric oxide (NO) sensing.5 Overexpression of UCP1 (UCP1ox) resulted in the stabilization of an artificial PCO N-degron pathway substrate, and stability of this reporter protein was influenced by pharmacological interventions that control UCP1 activity. Hypoxia and salt-tolerant phenotypes observed in UCP1ox lines resembled those observed for the PRT6 N-recognin E3 ligase mutant prt6-1. Genetic analysis showed that UCP1 regulation of hypoxia responses required the activity of PCO N-degron pathway ETHYLENE RESPONSE FACTOR (ERF)VII substrates. Transcript expression analysis indicated that UCP1 regulation of hypoxia-related gene expression is a normal component of seedling development. Our results show that mitochondrial retrog... Mostrar Tudo |
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Palavras-Chave: |
Expressão gênica; Resposta fisiológica. |
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Thesagro: |
Mitocôndria. |
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Thesaurus NAL: |
Arabidopsis thaliana; Gene expression; Gene overexpression; Hypoxia. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1149731/1/AP-Mitochondrial-retrograde-2022.pdf
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Marc: |
LEADER 02869naa a2200337 a 4500
001 2149731
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008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.cub.2022.01.037$2DOI
100 1 $aBARRETO, P.
245 $aMitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway.$h[electronic resource]
260 $c2022
500 $aShort communication. Na publicação: Juliana Yassitepe.
520 $aSUMMARY. Mitochondrial retrograde signaling is an important component of intracellular stress signaling in eukaryotes. UNCOUPLING PROTEIN (UCP)1 is an abundant plant inner-mitochondrial membrane protein with multiple functions including uncoupled respiration and amino-acid transport1,2 that influences broad abiotic stress responses. Although the mechanism(s) through which this retrograde function acts is unknown, overexpression of UCP1 activates expression of hypoxia (low oxygen)-associated nuclear genes.3,4 Here we show in Arabidopsis thaliana that UCP1 influences nuclear gene expression and physiological response by inhibiting the cytoplasmic PLANT CYSTEINE OXIDASE (PCO) branch of the PROTEOLYSIS (PRT)6 N-degron pathway, a major mechanism of oxygen and nitric oxide (NO) sensing.5 Overexpression of UCP1 (UCP1ox) resulted in the stabilization of an artificial PCO N-degron pathway substrate, and stability of this reporter protein was influenced by pharmacological interventions that control UCP1 activity. Hypoxia and salt-tolerant phenotypes observed in UCP1ox lines resembled those observed for the PRT6 N-recognin E3 ligase mutant prt6-1. Genetic analysis showed that UCP1 regulation of hypoxia responses required the activity of PCO N-degron pathway ETHYLENE RESPONSE FACTOR (ERF)VII substrates. Transcript expression analysis indicated that UCP1 regulation of hypoxia-related gene expression is a normal component of seedling development. Our results show that mitochondrial retrograde signaling represses the PCO N-degron pathway, enhancing substrate function, thus facilitating downstream stress responses. This work reveals a novel mechanism through which mitochondrial retrograde signaling influences nuclear response to hypoxia by inhibition of an ancient cytoplasmic pathway of eukaryotic oxygen sensing.
650 $aArabidopsis thaliana
650 $aGene expression
650 $aGene overexpression
650 $aHypoxia
650 $aMitocôndria
653 $aExpressão gênica
653 $aResposta fisiológica
700 1 $aDAMBIRE, C.
700 1 $aSHARMA, G.
700 1 $aVICENTE, J.
700 1 $aOSBORNE, R.
700 1 $aYASSITEPE, J. E. de C. T.
700 1 $aGIBBS, D. J.
700 1 $aMAIA, I. G.
700 1 $aHOLDSWORTH, M. J.
700 1 $aARRUDA, P.
773 $tCurrent Biology$gv. 32, n. 6, p. 1403-1411, Mar. 2022.
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