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| Registros recuperados : 241 | |
| 201. |  | PAPINE, J. M.; VIEIRA, M. S.; JARDINE, J. G.; NESHICH, G.; FALCÃO, P. R. K.; YAMAGISHI, M. E. B.; OLIVEIRA, S. R. de M.; MAZONI, I.; VIEIRA, F. D.; SANTOS, E. H. dos. Structural analysis of proplasmepsin from the human malarial pathogen plasmodium vivax In: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 14.; ANNUAL AB3C CONFERENCE, 2., 2006, Fortaleza. Conference Program... Fortaleza: ISCB, 2006. Não paginado. ISMB, X-MEETING 2006. Poster I-34. Na publicação: Paula R. Kuser-Falcão, Stanley R. M. Oliveira, Edgar H. Santos.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 202. | | OLIVEIRA, S. R. de M.; FALCÃO, P. R. K.; YAMAGISHI, M. E. B.; NESHICH, G.; RODRIGUES, D. N.; SOUZA, K. R. R.; MORITA, D. U.; ALMEIDA, G. V.; MAZONI, I.; SANTOS, E. H. dos; VIEIRA, F. D.; JARDINE, J. G. STING database quality assessment. In: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 14.; ANNUAL AB3C CONFERENCE, 2., 2006, Fortaleza. Conference Program... Fortaleza: ISCB, 2006. Não paginado. ISMB, X-MEETING 2006. Poster B-33. Na publicação: Stanley R. M. Oliveira, Edgard H. Santos.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 203. | | OLIVEIRA, S. R. de M.; PAVANELLI, D. S.; ALMEIDA, G. V.; YAMAGISHI, M. E. B.; KUSER, P. R.; SANTOS, E. H. dos; VIEIRA, F. D.; MAZONI, I.; CRUZ, S. A. B. da; HIGA, R. H.; MANCINI, A. L.; NESHICH, G. STING_DB: a relational database of structural parameters for protein analysis. In: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional, 2005. p. 132. Na publicação: Paula R. Kuser, Edgard H. Santos. X-meeting 2005. Presented Posters.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 204. | | HIGA, R. H.; TOGAWA, R. C.; MONTAGNER, A. J.; PALANDRANI, J. C. F.; OKIMOTO, I. K. S.; FALCÃO, P. R. K.; YAMAGISHI, M. E. B.; MANCINI, A. L.; NESHICH, G. Sting Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes. BMC Bioinformatics, v. 5, p. 1-9, 2004. Na publicação: Paula R Kuser.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 205. | | HIGA, R. H.; TOGAWA, R. C.; MONTAGNER, A. J.; PALANDRANI, J. C. F.; OKIMOTO, I. K. S.; KUSER, P. R.; YAMAGISHI, M. E. B.; MANCINI, A. L.; NESHICH, G. Sting millennium suite: integrated software for extensive analyses of 3d structures of proteins and their complexes. BMC Bioinformatics, v. 5, n. 107, 2006.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 206. | | OLIVEIRA, S. R. de M.; ALMEIDA, G. V.; SOUZA, K. R. R.; RODRIGUES, D. N.; KUSER-FALCÃO, P. R.; YAMAGISHI, M. E. B.; SANTOS, E. H. dos; VIEIRA, F. D.; JARDINE, J. G.; NESHICH, G. Sting_RDB: a relational database of structural parameters for protein analysis with support for data warehousing and data mining. Genetics and Molecular Research, v. 6, n. 4, p. 911-922, 2007.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 207. | | NESHICH, G.; MANCINI, A. L.; YAMAGISHI, M. E. B.; FALCAO, P. R. K.; FILETO, R.; PINTO, I. P.; PALANDRANI, J. F.; KRAUCHENCO, J. N.; BAUDET, C.; MONTAGNER, A. J.; HIGA, R. H. STING Report: convenient web-based application for graphic and tabular presentations of protein sequence, structure and function descriptors from the STING database. Nucleic Acids Research, v. 33, p. D269-D274, 2005. Na publicação: Paula R. Kuser.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 208. | | LOBO, I. K. C.; NASCIMENTO, A. R. do; YAMAGISHI, M. E. B.; GUIGUEN, Y.; SILVA, G. F. da; SEVERAC, D.; AMARAL, A. da C.; REIS, V. R.; O'SULLIVAN, F. L. A. Transcriptome of tambaqui Colossoma macropomum during gonad differentiation: different molecular signals leading to sex identity. Genomics, v. 112, n. 3, p. 2478-2488, May 2020.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Amazônia Ocidental. |
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| 209. | | NESHICH, G.; FALCAO, P. R. K.; YAMAGISHI, M. E. B.; OLIVEIRA, S. R. de M.; MAZONI, I.; SANTOS, E. H. dos; VIEIRA, F. D.; CRUZ, S. A. B. da; MANCINI, A. L.; JARDINE, J. G.; HIGA, R. H. What makes the active site amino acids so different from the others: defining the structural descriptors specific for activity. In: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional, 2005. p. 149. Na publicação: Paula Kuser, Michel Yamagishi, Stanley Oliveira, Edgard Santos, Fabio Vieira, Sergio Cruz, Adauto Mancini, Roberto Higa. X-meeting 2005. Presented Posters.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 210. | | GOUVEIA, G. V.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. de A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518-524, oct. 2012.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 211. | | VENERONI-GOUVEIA, G.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518?524, 2011.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 212. | | VENERONI-GOUVEIA, G.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. de A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518-524, nov. 2012.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 213. | | GOUVEIA, J. J. de S.; PAIVA, S. R.; MCMANUS, C. M.; CAETANO, A. R.; KIJAS, J. W.; FACO, O.; AZEVEDO, H. C.; ARAUJO, A. M. de; SOUZA, C. J. H. de; YAMAGISHI, M. E. B.; CARNEIRO, P. L. S.; LOBO, R. N. B.; OLIVEIRA, S. M. P. de; SILVA, M. V. G. B. Genome-wide search for signatures of selection in three major Brazilian locally adapted sheep breeds. Livestock Science, n. 197, p. 36-45, 2017.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Caprinos e Ovinos; Embrapa Gado de Leite; Embrapa Meio-Norte; Embrapa Pecuária Sul; Embrapa Pesca e Aquicultura; Embrapa Recursos Genéticos e Biotecnologia; Embrapa Tabuleiros Costeiros; Embrapa Unidades Centrais. |
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| 214. | | NESHICH, G.; ROCCHIA, W.; MANCINI, A. L.; YAMAGISHI, M. E. B.; KUSER, P. R.; FILETO, R.; BAUDET, C.; PINTO, I. P.; MONTAGNER, A. J.; PALANDRANI, J. F.; KRAUCHENCO, J. N.; TORRES, R. C.; SOUZA, S.; TOGAWA, R. C.; HIGA, R. H. Java Protein Dossier: a novel web-based data visualization tool for comprehensive analysis of protein structure. Nucleic Acids Research, v. 32, W595-W601, 2004.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 215. | | YAMAGISHI, M. E. B.; BEZERRA, G. B. P.; QUINALIA, T.; KUSER, P. R.; HIGA, R. H.; MANCINI, A. L.; JARDINE, J. G.; MAZONI, I.; SANTOS, E. H. dos; CRUZ, S. A. B.; OLIVEIRA, S. R. M.; NESHICH, G.; RAY, N.; MAIGRET, B. An interative protein interface surface Java Viewer. In: X-MEETING; INTERNATIONAL CONFERENCE OF THE AB3C, 1., 2005, Caxambu. [Proceedings...]. [S.l.]: Associação Brasileira de Bioinformática e Biologia Computacional, 2005. p. 17. X-meeting 2005. Presented posters.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 216. | | PAIVA, S. R.; SILVA, M. V. G. B.; ANDRADE. L. G.; GUEDES, E.; MCMANUS, C.; YAMAGISHI, M. E. B.; CARNEIRO, P. L.; AZEVEDO, H. C.; FACO, O.; SOUZA, C. J. H. de; LOBO, R. N. B.; ARAUJO, A. M. de; MARTINS, V. M. V.; CAETANO, A. R. Development of a low density SNP panel for parentage and traceability testing in brazilian sheep breeds for optimization of breeding and conservation programs. In: Conference International Plant & Animal Genomes, 19., 2011, San Diego.| Biblioteca(s): Embrapa Caprinos e Ovinos; Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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| 217. | | NESHICH, G.; BORRO, L. C.; HIGA, R. H.; KUSER, P. R.; YAMAGISHI, M. E. B.; FRANCO, E. H.; KRAUCHENCO, J. N.; FILETO, R.; RIBEIRO, A. A.; BEZERRA, G. B. P.; VELLUDO, T. M.; JIMENEZ, T. S.; FURUKAWA, N.; TESHIMA, H.; KITAJIMA, K.; BAVA, A.; SARAI, A.; TOGAWA, R. C.; MANCINI, A. L. The Diamond Sting server. Nucleic Acids Research, v. 33, W29-W35, 2005.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 218. | | SOUSA, T. F.; ARAÚJO JÚNIOR, M. B. de; PERES, E. G.; SOUZA, M. P.; SILVA, F. M. A. da; MEDEIROS, L. S. de; SOUZA, A. D. L. de; SOUZA, A. Q. L. de S.; YAMAGISHI, M. E. B.; SILVA, G. F. da; KOOLEN, H. H. F.; QUEIROZ, M. V. de. Discovery of dual PKS involved in sclerotiorin biosynthesis in Penicillium meliponae using genome mining and gene knockout. Archives of Microbiology, v. 205, n. 2, 75, Feb. 2023.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Amazônia Ocidental. |
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| 219. | | NESHICH, G.; MAZONI, I.; OLIVEIRA, S. R. M.; YAMAGISHI, M. E. B.; KUSER-FALCÃO, P. R.; BORRO, L. C.; MORITA, D. U.; SOUZA, K. R. R.; ALMEIDA, G. V.; RODRIGUES, D. N.; JARDINE, J. G.; TOGAWA, R. C.; MANCINI, A. L.; HIGA, R. H.; CRUZ, S. A. B.; VIEIRA, F. D.; SANTOS, E. H.; MELO, R. C.; SANTORO, M. M. The Star STING server: a multiplatform environment for protein structure analysis. Genetics and Molecular Research, v. 5, n. 4, p. 717-722, 2006.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 220. | | FILETO, R.; KUSER, P. R.; YAMAGISHI, M. E. B.; RIBEIRO, A. A.; QUINALIA, T. G.; FRANCO, E. H.; MANCINI, A. L.; HIGA, R. H.; OLIVEIRA, S. R. M.; SANTOS, E. H.; VIEIRA, F. D.; MAZONI, I.; CRUZ, S. A. B.; NESHICH, G. PDB-Metrics: a web tool for exploring the PDB contents. Genetics and Molecular Research, v. 5, n. 2, p. 333-341, 2006.| Biblioteca(s): Embrapa Agricultura Digital. |
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| Registros recuperados : 241 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
19/05/2017 |
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Data da última atualização: |
30/12/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; COLE, J. B.; SILVA, M. V. G. B. |
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Afiliação: |
NEDENIA BONVINO STAFUZZA, FCAV/Unesp; ADHEMAR ZERLOTINI NETO, CNPTIA; FRANCISCO PEREIRA LOBO, CNPTIA; MICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; TATIANE CRISTINA SELEGUIM CHUD, FCAV/Unesp; ALEXANDRE RODRIGUES CAETANO, Cenargen; DANÍSIO PRADO MUNARI, FCAV/Unesp; DORIAN J. GARRICK, Iowa State University; MARCO ANTONIO MACHADO, CNPGL; MARTA FONSECA MARTINS, CNPGL; MARIA RAQUEL CARVALHO, UFMG; JOHN BRUCE COLE, Agricultural Research Service; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
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Título: |
Single nucleotide variants and InDels identified from whole-genome re-sequencing of Guzerat, Gyr, Girolando and Holstein cattle breeds. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Plos One, v. 12, n. 3, p. 1-15, 2017. |
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DOI: |
https://doi.org/10.1371/journal.pone.0173954 |
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Idioma: |
Inglês |
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Notas: |
Artigo e0173954. Na publicação: Adhemar Zerlotini, Marcos Vinicius Gualberto Barbosa da Silva. |
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Conteúdo: |
Whole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated molecular mechanisms that impact economically important traits for Gyr, Girolando, Guzerat and Holstein breeding programs. MenosWhole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated... Mostrar Tudo |
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Palavras-Chave: |
Genetic variants; Genomic markers; Important traits; Molecular mechanisms; Polimorfismo de nucleotídeo único; Potential genomic markers; Raças bovinas; Single nucleotide variations. |
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Thesagro: |
Gado; Variação genética. |
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Thesaurus NAL: |
Cattle breeds; Genome; Single nucleotide polymorphism; Sires. |
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Categoria do assunto: |
--
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/171980/1/AP-Single-nucleotide-Stafuzza-etal.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/161515/1/Cnpgl-2017-PlosOne-Stafuzza-Single.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/180929/1/journal.pone.0173954.pdf
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Marc: |
LEADER 03086naa a2200457 a 4500
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008 2017 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1371/journal.pone.0173954$2DOI
100 1 $aSTAFUZZA, N. B.
245 $aSingle nucleotide variants and InDels identified from whole-genome re-sequencing of Guzerat, Gyr, Girolando and Holstein cattle breeds.$h[electronic resource]
260 $c2017
500 $aArtigo e0173954. Na publicação: Adhemar Zerlotini, Marcos Vinicius Gualberto Barbosa da Silva.
520 $aWhole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated molecular mechanisms that impact economically important traits for Gyr, Girolando, Guzerat and Holstein breeding programs.
650 $aCattle breeds
650 $aGenome
650 $aSingle nucleotide polymorphism
650 $aSires
650 $aGado
650 $aVariação genética
653 $aGenetic variants
653 $aGenomic markers
653 $aImportant traits
653 $aMolecular mechanisms
653 $aPolimorfismo de nucleotídeo único
653 $aPotential genomic markers
653 $aRaças bovinas
653 $aSingle nucleotide variations
700 1 $aZERLOTINI NETO, A.
700 1 $aLOBO, F. P.
700 1 $aYAMAGISHI, M. E. B.
700 1 $aCHUD, T. C. S.
700 1 $aCAETANO, A. R.
700 1 $aMUNARI, D. P.
700 1 $aGARRICK, D. J.
700 1 $aMACHADO, M. A.
700 1 $aMARTINS, M. F.
700 1 $aCARVALHO, M. R.
700 1 $aCOLE, J. B.
700 1 $aSILVA, M. V. G. B.
773 $tPlos One$gv. 12, n. 3, p. 1-15, 2017.
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Embrapa Agricultura Digital (CNPTIA) |
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