Data/hora: 23/09/2024 11:59:07

Biblioteca(s): 	Embrapa Agricultura Digital.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	Internacional - A	
Data corrente: 	10/12/2007	
Data da última atualização: 	11/05/2017	
Autoria: 	YAMAGISHI, M. E. B.; SHIMABUKURO, A. I.	
Afiliação: 	MICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; ALEX ITIRO SHIMABUKURO, PUC-Campinas.	
Título: 	Nucleotide frequencies in human genome and Fibonacci numbers.	
Ano de publicação: 	2008	
Fonte/Imprenta: 	Bulletin of Mathematical Biology, v. 70, n. 3, p. 643-653, Apr. 2008.	
DOI: 	10.1007/s11538-007-9261-6	
Idioma: 	Inglês	
Conteúdo: 	Abstract. This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions. First, Chargaff's second parity rule should be valid, and second, the nucleotide frequencies should approach limit values when the number of bases is sufficiently large. Under these two hypotheses, it is possible to predict the human nucleotide frequencies with accuracy. This result may be used as evidence to the Fibonacci string model that was proposed to the sequence growth of DNA repetitive sequences. It is noteworthy that the predicted values are solutions of an optimization problem, which is commonplace in many of nature's phenomena.	
Palavras-Chave: 	Chargaff's parity rules; Fibonacci numbers; Genoma humano; Nucleotide frequencies; Números de Fibonacci; Optimization problem.	
Thesagro: 	Modelo matemático.	
Thesaurus Nal: 	Mathematical models; Nucleotides; Repetitive sequences; System optimization.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/159709/1/AP-Nucleotide-Yamagishi-2008.pdf	
Registro original: 	Embrapa Agricultura Digital (CNPTIA)	
Exemplares: 	CNPTIA - (11666-1) - UPC - AP - -- -  -  - 2007.00049 - DES
CNPTIA - (11666-2) - UPC - AP - DD -  -  -  - DIS