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Registros recuperados : 7 | |
1. | | TRIBULO, P.; SIQUEIRA, L. G. B.; HANSEN, P. J. Endometrial expression of genes involved in growth factor, cytoline, hormone, and WNT signaling during the early estrous cycle of the cow In: ANNUAL MEETING OF THE SOCIETY FOR THE STUDY OF REPRODUCTION, 48., 2015, San Juan, Puerto Rico, USA. Evolution of sex: abstracts. San Juan: SSR, 2015. P. 113. Biblioteca(s): Embrapa Gado de Leite. |
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4. | | LI, Y.; TRÍBULO, P.; BAKHTIARIZADEH, M. R.; SIQUEIRA, L. G. B.; JI, T.; RIVERA, R. M.; HANSEN, P. J. Conditions of embryo culture from days 5 to 7 of development alter the DNA methylome of the bovine fetus at day 86 of gestation. Journal of Assisted Reproduction and Genetics, v. 37, p. 417-426, 2020. Biblioteca(s): Embrapa Gado de Leite. |
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5. | | ORTEGA, M. S.; WOHLGEMUTH, S.; TRIBULO, P.; SIQUEIRA, L. G. B.; NULL, D. J.; COLE, J. B.; SILVA, M. V. G. B.; HANSEN, P. J. A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows. Biology of Reproduction, v. 96, n. 3, p. 652-663, 2017. Biblioteca(s): Embrapa Gado de Leite. |
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6. | | SIQUEIRA, L. G. B.; TRIBULO, P.; DENICOL, A. C.; ORTEGA, M. S.; NEGRON-PEREZ, V.M.; KANNAMPUZHA-FRANCIS, J. P.; HANSEN, P. J. Consequences of in vitro production of embryos with or whithout colony-stimulating factor 2 in culture medium on morphometric features of the bovine conceptus at day 86 of gestation In: ANNUAL CONFERENCE OF THE INTERNATIONAL EMBRYO TRANSFER SOCIETY, 2016, Louisville. Reproduction, fertility and development: proceedings. Louisville: [s.n.], 2016. Biblioteca(s): Embrapa Gado de Leite. |
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7. | | SIQUEIRA, L. G. B.; TRIBULO, P.; CHEN, Z.; DENICOL, A. C.; ORTEGA, M. S.; NEGRON-PEREZ, V.M.; KANNAMPUZHA-FRANCIS, J. P.; POHLER, K. G.; RIVERA, R. M.; HANSEN, P. J. Colony-stimulating factor 2 acts from days 5 to 7 of development to modify programming of the bovine conceptus at day 86 of gestation. Biology of Reproduction, v. 96, n. 4, p. 743-757, 2017. Biblioteca(s): Embrapa Gado de Leite. |
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Registros recuperados : 7 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
12/12/2017 |
Data da última atualização: |
10/08/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
SIQUEIRA, L. G. B.; TRIBULO, P.; CHEN, Z.; DENICOL, A. C.; ORTEGA, M. S.; NEGRON-PEREZ, V.M.; KANNAMPUZHA-FRANCIS, J. P.; POHLER, K. G.; RIVERA, R. M.; HANSEN, P. J. |
Afiliação: |
LUIZ GUSTAVO BRUNO SIQUEIRA, CNPGL; P. TRIBULO, UNIVERSITY OF FLORIDA/USA; Zhiyuan Chen, University of Missouri, Columbia, MO; A. C. DENICOL, UNIVERSITY OF FLORIDA/USA; M. S. ORTEGA, UNIVERSITY OF FLORIDA/USA; V. M. NEGRON-PEREZ, UNIVERSITY OF FLORIDA/USA; J. P. KANNAMPUZHA-FRANCIS, UNIVERSITY OF FLORIDA/USA; Ky G. Pohler, University of Tennessee, Knoxville, TN; Rocio M. Rivera, University of Missouri, Columbia, MO; P. J. HANSEN, UNIVERSITY OF FLORIDA/USA. |
Título: |
Colony-stimulating factor 2 acts from days 5 to 7 of development to modify programming of the bovine conceptus at day 86 of gestation. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Biology of Reproduction, v. 96, n. 4, p. 743-757, 2017. |
DOI: |
http://doi.org/10.1093/biolre/iox018 |
Idioma: |
Inglês |
Conteúdo: |
Colony-stimulating factor 2 (CSF2) is an embryokine that improves competence of the embryo to establish pregnancy and which may participate in developmental programming. We tested whether culture of bovine embryos with CSF2 alters fetal development and alleviates abnormalities associated with in vitro production (IVP) of embryos. Pregnancies were established by artificial insemination (AI), transfer of an IVP embryo (IVP) or transfer of an IVP embryo treated with 10 ng/ml CSF2 from day 5 to 7 of development (CSF2). Pregnancies were produced using X-sorted semen from a single sire. Female singleton conceptuses were collected on day 86 of gestation. There were few morphological differences between groups although IVP and CSF2 fetuses were heavier than AI fetuses. Bicarbonate concentration in allantoic fluid was lower for IVP than for AI or CSF2. Expression of 92 genes in liver, placenta, and muscle was determined by RT-qPCR. The general pattern for liver and placenta was for IVP to alter expression and for CSF2 to sometimes reverse this effect. For muscle, CSF2 affected gene expression but did not generally reverse effects of IVP. Levels of methylation for each of the three tissues at 12 loci in the promoter of IGF2 and five in the promoter of GRB10 were unaffected by treatment except for CSF2 effects on two CpG for IGF2 in placenta and muscle. In conclusion, CSF2 can act as a developmental programming agent but alone is not able to abolish the adverse effects of in vitro production on fetal characteristics. MenosColony-stimulating factor 2 (CSF2) is an embryokine that improves competence of the embryo to establish pregnancy and which may participate in developmental programming. We tested whether culture of bovine embryos with CSF2 alters fetal development and alleviates abnormalities associated with in vitro production (IVP) of embryos. Pregnancies were established by artificial insemination (AI), transfer of an IVP embryo (IVP) or transfer of an IVP embryo treated with 10 ng/ml CSF2 from day 5 to 7 of development (CSF2). Pregnancies were produced using X-sorted semen from a single sire. Female singleton conceptuses were collected on day 86 of gestation. There were few morphological differences between groups although IVP and CSF2 fetuses were heavier than AI fetuses. Bicarbonate concentration in allantoic fluid was lower for IVP than for AI or CSF2. Expression of 92 genes in liver, placenta, and muscle was determined by RT-qPCR. The general pattern for liver and placenta was for IVP to alter expression and for CSF2 to sometimes reverse this effect. For muscle, CSF2 affected gene expression but did not generally reverse effects of IVP. Levels of methylation for each of the three tissues at 12 loci in the promoter of IGF2 and five in the promoter of GRB10 were unaffected by treatment except for CSF2 effects on two CpG for IGF2 in placenta and muscle. In conclusion, CSF2 can act as a developmental programming agent but alone is not able to abolish the adverse effects of in vitro prod... Mostrar Tudo |
Palavras-Chave: |
Colony-stimulating factor 2; Embryokine; Programming. |
Thesaurus NAL: |
fetal development. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02445naa a2200289 a 4500 001 2082306 005 2022-08-10 008 2017 bl uuuu u00u1 u #d 024 7 $ahttp://doi.org/10.1093/biolre/iox018$2DOI 100 1 $aSIQUEIRA, L. G. B. 245 $aColony-stimulating factor 2 acts from days 5 to 7 of development to modify programming of the bovine conceptus at day 86 of gestation.$h[electronic resource] 260 $c2017 520 $aColony-stimulating factor 2 (CSF2) is an embryokine that improves competence of the embryo to establish pregnancy and which may participate in developmental programming. We tested whether culture of bovine embryos with CSF2 alters fetal development and alleviates abnormalities associated with in vitro production (IVP) of embryos. Pregnancies were established by artificial insemination (AI), transfer of an IVP embryo (IVP) or transfer of an IVP embryo treated with 10 ng/ml CSF2 from day 5 to 7 of development (CSF2). Pregnancies were produced using X-sorted semen from a single sire. Female singleton conceptuses were collected on day 86 of gestation. There were few morphological differences between groups although IVP and CSF2 fetuses were heavier than AI fetuses. Bicarbonate concentration in allantoic fluid was lower for IVP than for AI or CSF2. Expression of 92 genes in liver, placenta, and muscle was determined by RT-qPCR. The general pattern for liver and placenta was for IVP to alter expression and for CSF2 to sometimes reverse this effect. For muscle, CSF2 affected gene expression but did not generally reverse effects of IVP. Levels of methylation for each of the three tissues at 12 loci in the promoter of IGF2 and five in the promoter of GRB10 were unaffected by treatment except for CSF2 effects on two CpG for IGF2 in placenta and muscle. In conclusion, CSF2 can act as a developmental programming agent but alone is not able to abolish the adverse effects of in vitro production on fetal characteristics. 650 $afetal development 653 $aColony-stimulating factor 2 653 $aEmbryokine 653 $aProgramming 700 1 $aTRIBULO, P. 700 1 $aCHEN, Z. 700 1 $aDENICOL, A. C. 700 1 $aORTEGA, M. S. 700 1 $aNEGRON-PEREZ, V.M. 700 1 $aKANNAMPUZHA-FRANCIS, J. P. 700 1 $aPOHLER, K. G. 700 1 $aRIVERA, R. M. 700 1 $aHANSEN, P. J. 773 $tBiology of Reproduction$gv. 96, n. 4, p. 743-757, 2017.
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