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| Registros recuperados : 475 | |
| 108. |  | CARDOSO, M. O.; PEREIRA, W. E.; OLIVEIRA, A. P. de; SOUZA, A. P. de. Teores de macronutrientes em folhas de berinjela em função de doses de esterco bovino e termofosfato magnesiano. In: CONGRESSO BRASILEIRO DE OLERICULTURA, 46., 2006, Goiânia. [Anais... ]. Horticultura Brasileira, v. 24, n. 1, p. 3138-3141, jul. 2006. Supl. CD-ROM.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 109. | | CARDOSO, M. O.; PEREIRA, W. E.; OLIVEIRA, A. P. de; SOUZA, A. P. de. Teores de macronutrientes em folhas de berinjela em função de doses de esterco bovino e termofosfato magnesiano. In: CONGRESSO BRASILEIRO DE OLERICULTURA, 46., 2006, Goiânia. Horticultura Brasileira, v. 24, n. 1, p. 253, jul. 2006. Suplemento.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 110. | | ANTUNES, C. L.; SOUZA, A. P.; BÔAS, R. L. V.; ANTUNES, E. A. Teor e acúmulo de cálcio e potássio em alface americana sob fertirrigação nitrogenada e épocas de aplicação de GA3. Horticultura Brasileira, Brasília, DF, v. 20, n. 2, jul. 2002. Suplemento 2. 1 CD-ROM. Trabalho apresentado no 42º Congresso Brasileiro de Olericultura, 2002. Publicado também como resumo em: Horticultura Brasileira, Brasília, DF, v. 20, n. 2, p. 281, jul. 2002. Suplemento 1.| Biblioteca(s): Embrapa Hortaliças. |
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| 113. | | SOUZA, A. P.; MACHADO, C. C.; GRIFFITH, J. J.; NEVES, A. R. Controle de impacto ambiental na exploração florestal: proposta de normas. Silvicultura, São Paulo, v. 12, n. 42, t. 32, p. 301-305, 1992. Edição dos Anais do Congresso Florestal Brasileiro, 6., 1990, Campos do Jordão.| Biblioteca(s): Embrapa Florestas. |
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| 114. | | CARDOSO, M. O.; PEREIRA, W. E.; OLIVEIRA, A. P. de; SOUZA, A. P. de. Correlações canônicas entre características do crescimento com características químicas do substrato em berinjela. In: CONGRESSO BRASILEIRO DE OLERICULTURA, 47.; SIMPÓSIO BRASILEIRO SOBRE CUCURBITÁCEAS, 4., 2007, Porto Seguro, BA. Resgatando e valorizando as hortaliças subutilizadas. Horticultura Brasileira, v. 25, n. 1, ago. 2007. 1 CD-ROM.| Biblioteca(s): Embrapa Amazônia Ocidental. |
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| 116. | | VIGNA, B. B. Z.; JUNGMANN, L.; PAIVA, J.; VALLE, C. B. do; SOUZA, A. P. Diversidade genética do banco de germoplasma de Brachiaria humidicola, uma gramínea forrageira tropical. In: CONGRESSO BRASILEIRO DE GENÉTICA, 54., 2008, Salvador. Anais. Salvador: SBG, 2008. p. 56| Biblioteca(s): Embrapa Gado de Corte. |
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| 117. | | SOUZA, A. P. de; ÁLVAREZ-SANCHEZ, M. A.; PÉREZ-GARCÍ, J.; ROJO-VÁZQUEZ, E. A. Dose letal 50 de Thiabendazole, em relação ao período de infecção por Haemonchus contortus, Teladorsagia circumcincta e Trichostrongylus spp. em ovinos. Revista Brasileira de Parasitologia Veterinária, Rio de Janeiro, v. 12, n. 2, p. 49-52, 2003.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 119. | | SILVA, C. R. P.; DEMARQUI, E. N.; TERRA, F. A.; MINGOTI, R.; SOUZA, A. P. Diferentes modelos digitais de elevação na caracterização física da bacia hidrográfica do Rio Nandico, MT, Brasil. Scientia Plena, v. 11, p. 1-11, 2015. v. 11 p. 1-11| Biblioteca(s): Embrapa Territorial. |
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| Registros recuperados : 475 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
15/03/2019 |
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Data da última atualização: |
02/12/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
DINIZ, W. J. S.; MAZZONI, G.; COUTINHO; BANERJEE, P.; GEISTLINGER, L.; CESAR, A. S. M.; BERTOLINI. F.; AFONSO, J.; OLIVEIRA, P. S. N.; TIZIOTO, P. C.; KADARMIDEEN, H. N.; REGITANO, L. C. de A. |
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Afiliação: |
Wellison J. S. Diniz, UFSCAR; Gianluca Mazzoni, Technical University of Denmark; Luiz L. Coutinho, USP; Priyanka Banerjee, Technical University of Denmark; Ludwig Geistlinger, Graduate School of Public Health and Health Policy; Aline S. M. Cesar, USP; Francesca Bertolini, Technical University of DenmarK; Juliana Afonso, UFSCAR; Priscila S. N. de Oliveira, Bolsista/Embrapa Pecuária Sudeste; Polyana C. Tizioto, USP; Haja N. Kadarmideen, Technical University of Denmark; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Detection of Co-expressed pathway modules associated with mineral concentration and meat quality in nelore cattle. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Frontiers in genetics, v. 10, n. 210, p. 1-12, 2019. |
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DOI: |
10.3389/fgene.2019.00210 |
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Idioma: |
Inglês |
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Conteúdo: |
Meat quality is a complex trait that is influenced by genetic and environmental factors, which includes mineral concentration. However, the association between mineral concentration and meat quality, and the specific molecular pathways underlying this association, are not well explored. We therefore analyzed gene expression as measured with RNA-seq in Longissimus thoracis muscle of 194 Nelore steers for association with three meat quality traits (intramuscular fat, meat pH, and tenderness) and the concentration of 13 minerals (Ca, Cr, Co, Cu, Fe, K, Mg, Mn, Na, P, S, Se, and Zn). We identified seven sets of co-expressed genes (modules) associated with at least two traits, which indicates that common pathways influence these traits. From pathway analysis of module hub genes, we further found an over-representation for energy and protein metabolism (AMPK and mTOR signaling pathways) in addition to muscle growth, and protein turnover pathways. Among the identified hub genes FASN, ELOV5, and PDE3B are involved with lipid metabolism and were affected by previously identified eQTLs associated to fat deposition. The reported hub genes and over-represented pathways provide evidence of interplay among gene expression, mineral concentration, and meat quality traits. Future studies investigating the effect of different levels of mineral supplementation in the gene expression and meat quality traits could help us to elucidate the regulatory mechanism by which the genes/pathways are affected. MenosMeat quality is a complex trait that is influenced by genetic and environmental factors, which includes mineral concentration. However, the association between mineral concentration and meat quality, and the specific molecular pathways underlying this association, are not well explored. We therefore analyzed gene expression as measured with RNA-seq in Longissimus thoracis muscle of 194 Nelore steers for association with three meat quality traits (intramuscular fat, meat pH, and tenderness) and the concentration of 13 minerals (Ca, Cr, Co, Cu, Fe, K, Mg, Mn, Na, P, S, Se, and Zn). We identified seven sets of co-expressed genes (modules) associated with at least two traits, which indicates that common pathways influence these traits. From pathway analysis of module hub genes, we further found an over-representation for energy and protein metabolism (AMPK and mTOR signaling pathways) in addition to muscle growth, and protein turnover pathways. Among the identified hub genes FASN, ELOV5, and PDE3B are involved with lipid metabolism and were affected by previously identified eQTLs associated to fat deposition. The reported hub genes and over-represented pathways provide evidence of interplay among gene expression, mineral concentration, and meat quality traits. Future studies investigating the effect of different levels of mineral supplementation in the gene expression and meat quality traits could help us to elucidate the regulatory mechanism by which the genes/pathways are affe... Mostrar Tudo |
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Palavras-Chave: |
AMPK pathway; Co-expression analysis; RNA sequencing; Tenderness. |
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Thesagro: |
Gado de Corte; Gordura Animal. |
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Thesaurus NAL: |
Beef cattle; Beef quality; Intramuscular fat. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/194304/1/fgene-10-00210.pdf
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Marc: |
LEADER 02585naa a2200373 a 4500
001 2107117
005 2019-12-02
008 2019 bl uuuu u00u1 u #d
024 7 $a10.3389/fgene.2019.00210$2DOI
100 1 $aDINIZ, W. J. S.
245 $aDetection of Co-expressed pathway modules associated with mineral concentration and meat quality in nelore cattle.$h[electronic resource]
260 $c2019
520 $aMeat quality is a complex trait that is influenced by genetic and environmental factors, which includes mineral concentration. However, the association between mineral concentration and meat quality, and the specific molecular pathways underlying this association, are not well explored. We therefore analyzed gene expression as measured with RNA-seq in Longissimus thoracis muscle of 194 Nelore steers for association with three meat quality traits (intramuscular fat, meat pH, and tenderness) and the concentration of 13 minerals (Ca, Cr, Co, Cu, Fe, K, Mg, Mn, Na, P, S, Se, and Zn). We identified seven sets of co-expressed genes (modules) associated with at least two traits, which indicates that common pathways influence these traits. From pathway analysis of module hub genes, we further found an over-representation for energy and protein metabolism (AMPK and mTOR signaling pathways) in addition to muscle growth, and protein turnover pathways. Among the identified hub genes FASN, ELOV5, and PDE3B are involved with lipid metabolism and were affected by previously identified eQTLs associated to fat deposition. The reported hub genes and over-represented pathways provide evidence of interplay among gene expression, mineral concentration, and meat quality traits. Future studies investigating the effect of different levels of mineral supplementation in the gene expression and meat quality traits could help us to elucidate the regulatory mechanism by which the genes/pathways are affected.
650 $aBeef cattle
650 $aBeef quality
650 $aIntramuscular fat
650 $aGado de Corte
650 $aGordura Animal
653 $aAMPK pathway
653 $aCo-expression analysis
653 $aRNA sequencing
653 $aTenderness
700 1 $aMAZZONI, G.
700 1 $aCOUTINHO
700 1 $aBANERJEE, P.
700 1 $aGEISTLINGER, L.
700 1 $aCESAR, A. S. M.
700 1 $aBERTOLINI. F.
700 1 $aAFONSO, J.
700 1 $aOLIVEIRA, P. S. N.
700 1 $aTIZIOTO, P. C.
700 1 $aKADARMIDEEN, H. N.
700 1 $aREGITANO, L. C. de A.
773 $tFrontiers in genetics$gv. 10, n. 210, p. 1-12, 2019.
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Embrapa Pecuária Sudeste (CPPSE) |
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