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Registros recuperados : 150 | |
101. | | ROCHA, M. I. P.; SOUZA, M. M. de; ZERLOTINI NETO, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LIMA, A. O. de; AFONSO, J.; DINIZ, W. J. da S.; BUSS, C. E.; COUTINHO, L. L.; REGITANO, L. C. de A.; NICIURA, S. C. M. LDHB gene has allele-specific expression in liver of Nelore cattle extremes for feed efficiency. In: WORKSHOP ON OMICS STRATEGIES APPLIED TO LIVESTOCK SCIENCE, 1., 2017, Piracicaba, SP. Proceedings... São Carlos, SP: Embrapa Pecuária Sudeste, 2017. p. 25. (Embrapa Pecuária Sudeste. Documentos, 125) Editores: Luiz Lehmann Coutinho, ESALQ/USP; Luciana Correia de Almeida Regitano, Embrapa Pecuária Sudeste; Gerson Barreto Mourão, ESALQ/USP; Aline Silva Mello Cesar, ESALQ/USP; Bárbara Silva Vignato, FZEA/USP; Mirele Daiana Poleti,... Biblioteca(s): Embrapa Pecuária Sudeste. |
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102. | | OLIVEIRA, P. S. N. de; COUTINHO, L. L.; TIZIOTO, P. C.; CESAR, A. S. M.; OLIVEIRA, G. B. de; DINIZ, W, J. da S.; LIMA, A. O. de; REECY, J. M.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REGITANO, L. C. de A. An integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle. Scientific Reports, v. 8, p. 1-12, 2018. Article number: 17072. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano. Biblioteca(s): Embrapa Agricultura Digital. |
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103. | | OLIVEIRA, P. S. N. de; COUTINHO, L. L.; TIZIOTO, P. C.; CESAR, A. S. M.; OLIVEIRA, G. B. de; DINIZ, W, J. da S.; LIMA, A. O. de; REECY, J. M.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REGITANO, L. C. de A. An integrative transcriptome analysis indicates regulatory mRNA-miRNA networks for residual feed intake in Nelore cattle. Scientific Reports, v. 8, n. 17072, 2018. Biblioteca(s): Embrapa Pecuária Sudeste. |
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104. | | TIZIOTO, P.; COUTINHO, L. L.; DECKER, J. E.; SCHNABEL, R. D.; ROSA, C. O.; OLIVEIRA, P. S. N.; SOUZA, M. M.; MOURÃO, G. B.; TULLIO, R. R.; CHAVES, A. S.; LANNA, D. P. D.; ZERLOTINI NETO, A.; MUDADU, M. A.; TAYLOR, J. F.; REGITANO, L. C. A. Global liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes. BMC Genomics, London, v. 16, p. 1-14, 2015. Biblioteca(s): Embrapa Agricultura Digital. |
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105. | | TIZIOTO, P.; COUTINHO, L. L.; DECKER, J. E.; SCHNABEL, R. D.; ROSA, K. O.; OLIVEIRA, P. S. N.; SOUZA, M. M.; MOURÃO, G. B.; TULLIO, R. R.; CHAVES, A. S.; LANNA, D. P. D.; ZERLOTINI NETO, A.; MUDADU, M. de A.; TAYLOR, J. F.; REGITANO, L. C. de A. Global liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes. BMC Genomics, v. 16, n. 242, 2015. Biblioteca(s): Embrapa Pecuária Sudeste. |
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106. | | BUSS, C. E.; DINIZ, W. J. da S.; ANDRADE, B. G.; LIMA, A. O. de; GEISTLINGER, L.; AFONSO, J.; TULLIO, R. R.; TIZIOTO, P. C.; PETRINI, J.; COUTINHO, L. L.; WOLF, J. B.; MOURAO, G. B.; REGITANO, L. C. de A. Identification of pleiotropic loci for daily weight gain and intramuscular fat in cattle using bivariate genome-wide association analysis. In: INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE, 36., 2017, Dublin. Proceedings... Dublin: University College Dublin, 2017. p. 161-162. Biblioteca(s): Embrapa Pecuária Sudeste. |
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107. | | BUSS, C. E.; PETRINI, J.; MOURAO, G. B.; GEISTLINGER, L.; WOLF, J. B.; DINIZ, W. J. da S.; ROCHA, M. I. P.; AFONSO, J.; LIMA, A. O. de; TIZIOTO, P. C.; TULLIO, R. R.; ANDRADE, B. G.; COUTINHO, L. L.; REGITANO, L. C. de A. Identification of a pleiotropic locus for beef quality and feed efficiency in cattle using bi-trait genome-wide association analysis. In: WORKSHOP ON OMICS STRATEGIES APPLIED TO LIVESTOCK SCIENCE, 1., 2017, Piracicaba, SP. Proceedings... São Carlos, SP: Embrapa Pecuária Sudeste, 2017. p. 22. (Embrapa Pecuária Sudeste. Documentos, 125) Editores: Luiz Lehmann Coutinho, ESALQ/USP; Luciana Correia de Almeida Regitano, Embrapa Pecuária Sudeste; Gerson Barreto Mourão, ESALQ/USP; Aline Silva Mello Cesar, ESALQ/USP; Bárbara Silva Vignato, FZEA/USP; Mirele Daiana Poleti,... Biblioteca(s): Embrapa Pecuária Sudeste. |
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108. | | CESAR, A. S. M.; REGITANO, L. C. de A.; REECY, J. M.; POLETI, M. D.; OLIVEIRA, P. S. N. de; OLIVEIRA, G. B. de; MOREIRA, G. C. M.; MUDADU, M. de A.; TIZIOTO, P. L.; KOLTES, J. E.; Fritz-Waters, E.; KRAMER, L.; GARRICK, D.; BEIKI, H.; GEISTLINGER, L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; COUTINHO, L. L. Identification of putative regulatory regions and transcription factors associated with intramuscular fat content traits. BMC Genomics, v. 19, p. 1-20, 2018. Article number: 499. Na publicação: Luciana C. A. Regitano, Maurício A. Mudadu, Adhemar Zerlotini. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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109. | | AFONSO, J.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; DINIZ, W. J. da S.; LIMA, A. O. de; SOUZA, M. M. de; ROCHA, M. I. P.; SILVA, J. V. da; BUSS, C. E.; GROMBONI, C. F.; MOURAO, G. B.; NOGUEIRA, A. R. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. Identification of genes associated with copper-deficient fatty acid increase in Nelore cattle. In: INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE, 36., 2017, Dublin. Proceedings... Dublin: University College Dublin, 2017. p. 161. Biblioteca(s): Embrapa Pecuária Sudeste. |
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110. | | OLIVEIRA, P. S. N.; CESAR, A. S. M.; NASCIMENTO, M. L. do; CHAVES, A. S.; TIZIOTO, P. C.; TULLIO, R. R.; LANNA, D. P. D.; ROSA, A. do N.; SONSTEGARD, T. S.; MOURÃO, G. B.; REECY, J. M.; GARRICK, D. J.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. Identification of genomic regions associated with feed efficiency in Nelore cattle. BMC Genetics, v. 15, n. 1, 2014 10 p. Biblioteca(s): Embrapa Pecuária Sudeste. |
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111. | | TIZIOTO, P. C.; GASPARIN, G.; SOUZA, M. M.; MUDADU, M. de A.; COUTINHO, L. L.; MOURÃO, G. B.; THOLON, P.; MEIRELLES, S. L. C.; TULLIO, R. R.; ROSA, A. do N.; ALENCAR, M. M. de; MEDEIROS, S. R. de; SIQUEIRA, F.; FEIJO, G. L. D.; NASSU, R. T.; REGITANO, L. C. de A. Identification of KCNJ11 as a functional candidate gene for bovine meat tenderness. Physiological Genomics, v. 45, n. 24, p. 1215-1221, October 2013. Biblioteca(s): Embrapa Gado de Corte. |
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112. | | TIZIOTO, P.; GASPARINI, G.; SOUZA, M. M.; MUDADU, M. de A.; COUTINHO, L. L.; MOURÃO, G. B.; THOLON, P.; MEIRELLES, S. L. C.; TULLIO, R. R.; ROSA, A. do N.; ALENCAR, M. M. de; MEDEIROS, S. R.; SIQUEIRA, F.; FEIJO, G. L. D.; NASSU, R. T.; REGITANO, L. C. de A. Identification of KCNJ11 as a functional candidate gene for bovine meat tenderness. Physiological Genomics, v. 45, n. 24, p. 1215-1221, 2013. Biblioteca(s): Embrapa Pecuária Sudeste. |
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113. | | TIZIOTO, P.; DECKER, J.; TAYLOR, J.; SCHNABEL, R.; MUDADU, M. de A.; COUTINHO, L. L.; MOURÃO, G. B.; SONSTEGARD, T.; ROSA, A. do N.; ALENCAR, M. M. de; TULLIO, R. R.; MEDEIROS, S. R.; NASSU, R. T.; FEIJO, G. L. D.; SIQUEIRA, F.; REGITANO, L. C. de A. A Genome-Wide Association Study of Meat Tenderness in Nelore Beef Cattle. In: PLANT ANIMAL GENOME CONFERENCE 21, 2013, San-Diego. abstract...San Diego: INTLPAG, 2013. P0573 Biblioteca(s): Embrapa Pecuária Sudeste. |
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114. | | SOUZA, M. M.; ZERLOTINI NETO, A.; NICIURA, S. C. M.; ROCHA, M. I. P.; DINIZ, W. J.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; LIMA, A. O.; AFONSO, J.; CESAR, A. S. M; COUTINHO, L. L.; REGITANO, L. C. de A. Genome-wide distribution of allele-specific expression in Nelore steers muscle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland. Proceedings... [S.l.: s.n.], 2018. 5 p. Na publicação: A. Zerlotini, L. C. A. Regitano. WCGALP 2018. Biblioteca(s): Embrapa Agricultura Digital. |
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115. | | SOUZA, M. M. de; ZERLOTINI NETO, A.; NICIURA, S. C. M.; ROCHA, M. I. P.; DINIZ, W. J.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LIMA, A. O.; AFONSO, J.; CESAR, A. S. M; COUTINHO, L. L.; REGITANO, L. C. de A. Genome-wide distribution of allele-specific expression in Nelore steers muscle. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOOCK PRODUCTION, 2018, Auckland, New Zealand. proceedings... Auckland, New Zealand: Massey University, 2018, v. 892. Biblioteca(s): Embrapa Pecuária Sudeste. |
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116. | | SOUZA, M. M.; ZERLOTINI NETO, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. de A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. de A. Monoallelic expression of NNAT gene in Nelore steers skeletal muscle. In:WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOK PRODUCTION, 10; . 2014, Vancouver. Proceedings... Vancouver: American Society of animal Science, 2014 Biblioteca(s): Embrapa Pecuária Sudeste. |
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117. | | TIZIOTO, P. C.; TAYLOR, J. F.; DECKER, J. E.; GROMBONI, C. F.; MUDADU, M. de A.; SCHNABEL, R. D.; COUTINHO, L. L.; MOURÃO, G. B.; NASSU, R. T.; DONATONI, F. A. B.; THOLON, P.; SONSTEGARD, T. S.; ALENCAR, M. M. de; TULLIO, R. R.; REECY, J. M.; NOGUEIRA, A. R. de A.; REGITANO, L. C. de A. Effects of quantitative trait loci on iron content of bovine longissimus dorsi muscle. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: American Society of Animal Science, 2014. 3 p. Biblioteca(s): Embrapa Pecuária Sudeste. |
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118. | | LIMA, A. O. de; OLIVEIRA, P. S. N. de; TIZIOTO, P. C.; AFONSO, J.; SOMAVILLA, A. L.; DINIZ, W. J. da S.; SILVA, J. V. da; ROCHA, M. I. P.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. Association analyses pointed the TIPARP as a potential candidate gene influencing residual feed intake variation in Nelore cattle. INTERNATIONAL MEETING OF ADVANCES IN ANIMAL SCIENCE, 1., 2016, Jaboticabal. Resumos... Jaboticabal: PPGZ Unesp, 2016. ref. 45135. Biblioteca(s): Embrapa Pecuária Sudeste. |
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119. | | TIZIOTO, P. C.; SOUZA, M. M. de; MUDADU, M. de A.; THOLON, P.; MEIRELLES, S. L. C.; TULLIO, R. R.; NASSU, R. T.; ROSA, A. do N.; MEDEIROS, S. R. de; SIQUEIRA, F.; FEIJO, G. L. D.; REGITANO, L. C. de A. Association of KCNJ11 gene variants with tenderness in Nelore breed. In: CONFERENCE OF INTERNATIONAL SOCIETY FOR ANIMAL GENETICS, 33., 2012, Cairns, AU. Abstracts... Cairns: ISAG, 2012. p.109-110 P4046 Biblioteca(s): Embrapa Gado de Corte; Embrapa Pecuária Sudeste. |
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120. | | CESAR, A. S. M.; REGITANO, L. C. de A.; POLETI, M. D.; ANDRADE, S. C. da S.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; LANNA, D. P. D.; TULLIO, R. R.; NASSU, R. T.; KOLTES, J. E.; WATERS, E. F.; REECY, J. M.; COUTINHO, L. L. Association of skeletal muscle transcripts with fatty acid content in Nellore cattle. In: INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE, 35., 2016, Salt Lake City. Proceedings... Salt Lake City: ISAG, 2016. Biblioteca(s): Embrapa Pecuária Sudeste. |
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Registro Completo
Biblioteca(s): |
Embrapa Agricultura Digital. |
Data corrente: |
05/02/2019 |
Data da última atualização: |
21/01/2020 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
SOUZA, M. M.; ZERLOTINI NETO, A.; NICIURA, S. C. M.; ROCHA, M. I. P.; DINIZ, W. J.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; LIMA, A. O.; AFONSO, J.; CESAR, A. S. M; COUTINHO, L. L.; REGITANO, L. C. de A. |
Afiliação: |
M. M. SOUZA, CPPSE; ADHEMAR ZERLOTINI NETO, CNPTIA; SIMONE CRISTINA MEO NICIURA, CPPSE; MARINA IBELLI PEREIRA ROCHA, UFSCar; WELLISON JARLES DINIZ, UFSCar; POLYANA CRISTINE TIZIOTO, Esalq/USP; PRISCILA SILVA NEUBERN DE OLIVEIRA, Bolsista/CPPSE; A.O. LIMA, UFSCar; J. AFONSO, UFSCar; A. S. M. CESAR, CNPTIA; L. L. COUTINHO, CNPTIA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Genome-wide distribution of allele-specific expression in Nelore steers muscle. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland. Proceedings... [S.l.: s.n.], 2018. |
Páginas: |
5 p. |
Idioma: |
Inglês |
Notas: |
Na publicação: A. Zerlotini, L. C. A. Regitano. WCGALP 2018. |
Conteúdo: |
Summary. The difference between the allelic expression of a gene is known as allele-specific expression (ASE), and it is a common event in mammal?s transcriptome. ASE is named genomic imprinting when guided by epigenetics mechanisms regarding the allele parental origin. Although these events are an important sources of phenotypic variation, knowledge thereof regarding cattle and effects on economically important traits are still incipient. Therefore, analysis and characterization of ASE profile in the muscle of adult Nelore animals were performed, and besides that, the ASE pattern and gene imprinting occurrence were checked in genes previously associated with meat tenderness. For this, RNA sequencing data of 146 Nelore steer muscles were used, and these animals were also genotyped for approximately 770,000 SNPs using Illumina BovineHD BeadChip. For each animal, a diploid genome was built based on their genotypes, and afterward, RNA-Seq reads were mapped to this genome. After counting the reads considering each SNP allele, a binomial test was applied to identify whether the allele contribution to total expression significantly diverged from 50%, followed by false discovery rate (FDR) test (0.05). Among 519 analyzed SNPs, 402 showed at least one sample with ASE, and they were spread among all autosomal chromosomes. SNPs showing ASE in more than five samples were tested regarding ASE extension, and most presented an incomplete pattern. Four ASE genes were previously identified in a Genome-Wide Association Study (GWAS) and five were found differentially expressed between extreme phenotype animals for meat tenderness. Therefore, the results will complement the bovine imprinted genes database, further they can provide new information to genetic effects prediction in animal breeding increasing the accuracy of meat tenderness selection. MenosSummary. The difference between the allelic expression of a gene is known as allele-specific expression (ASE), and it is a common event in mammal?s transcriptome. ASE is named genomic imprinting when guided by epigenetics mechanisms regarding the allele parental origin. Although these events are an important sources of phenotypic variation, knowledge thereof regarding cattle and effects on economically important traits are still incipient. Therefore, analysis and characterization of ASE profile in the muscle of adult Nelore animals were performed, and besides that, the ASE pattern and gene imprinting occurrence were checked in genes previously associated with meat tenderness. For this, RNA sequencing data of 146 Nelore steer muscles were used, and these animals were also genotyped for approximately 770,000 SNPs using Illumina BovineHD BeadChip. For each animal, a diploid genome was built based on their genotypes, and afterward, RNA-Seq reads were mapped to this genome. After counting the reads considering each SNP allele, a binomial test was applied to identify whether the allele contribution to total expression significantly diverged from 50%, followed by false discovery rate (FDR) test (0.05). Among 519 analyzed SNPs, 402 showed at least one sample with ASE, and they were spread among all autosomal chromosomes. SNPs showing ASE in more than five samples were tested regarding ASE extension, and most presented an incomplete pattern. Four ASE genes were previously identified ... Mostrar Tudo |
Palavras-Chave: |
Allele-specific expression; Expressão gênica; Sequenciamento; Sequencing; Transcriptoma. |
Thesagro: |
Gado Nelore; Melhoramento Genético Animal; Polimorfismo Genético. |
Thesaurus NAL: |
Gene expression; Transcriptome. |
Categoria do assunto: |
G Melhoramento Genético |
Marc: |
LEADER 03082nam a2200385 a 4500 001 2105522 005 2020-01-21 008 2018 bl uuuu u01u1 u #d 100 1 $aSOUZA, M. M. 245 $aGenome-wide distribution of allele-specific expression in Nelore steers muscle.$h[electronic resource] 260 $aIn: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland. Proceedings... [S.l.: s.n.], 2018.$c2018 300 $a5 p. 500 $aNa publicação: A. Zerlotini, L. C. A. Regitano. WCGALP 2018. 520 $aSummary. The difference between the allelic expression of a gene is known as allele-specific expression (ASE), and it is a common event in mammal?s transcriptome. ASE is named genomic imprinting when guided by epigenetics mechanisms regarding the allele parental origin. Although these events are an important sources of phenotypic variation, knowledge thereof regarding cattle and effects on economically important traits are still incipient. Therefore, analysis and characterization of ASE profile in the muscle of adult Nelore animals were performed, and besides that, the ASE pattern and gene imprinting occurrence were checked in genes previously associated with meat tenderness. For this, RNA sequencing data of 146 Nelore steer muscles were used, and these animals were also genotyped for approximately 770,000 SNPs using Illumina BovineHD BeadChip. For each animal, a diploid genome was built based on their genotypes, and afterward, RNA-Seq reads were mapped to this genome. After counting the reads considering each SNP allele, a binomial test was applied to identify whether the allele contribution to total expression significantly diverged from 50%, followed by false discovery rate (FDR) test (0.05). Among 519 analyzed SNPs, 402 showed at least one sample with ASE, and they were spread among all autosomal chromosomes. SNPs showing ASE in more than five samples were tested regarding ASE extension, and most presented an incomplete pattern. Four ASE genes were previously identified in a Genome-Wide Association Study (GWAS) and five were found differentially expressed between extreme phenotype animals for meat tenderness. Therefore, the results will complement the bovine imprinted genes database, further they can provide new information to genetic effects prediction in animal breeding increasing the accuracy of meat tenderness selection. 650 $aGene expression 650 $aTranscriptome 650 $aGado Nelore 650 $aMelhoramento Genético Animal 650 $aPolimorfismo Genético 653 $aAllele-specific expression 653 $aExpressão gênica 653 $aSequenciamento 653 $aSequencing 653 $aTranscriptoma 700 1 $aZERLOTINI NETO, A. 700 1 $aNICIURA, S. C. M. 700 1 $aROCHA, M. I. P. 700 1 $aDINIZ, W. J. 700 1 $aTIZIOTO, P. C. 700 1 $aOLIVEIRA, P. S. N. 700 1 $aLIMA, A. O. 700 1 $aAFONSO, J. 700 1 $aCESAR, A. S. M 700 1 $aCOUTINHO, L. L. 700 1 $aREGITANO, L. C. de A.
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