Data/hora: 20/06/2024 17:30:29

Biblioteca(s): 	Embrapa Pecuária Sudeste.	
Data corrente: 	21/10/2016	
Data da última atualização: 	07/11/2018	
Autoria: 	TIZIOTO, P. C.; COUTINHO, L. L.; GASPARIN, G.; MALAGO JUNIOR, W.; DONATONI, F. A. B.; TULLIO, R. R.; NASSU, R. T.; TAYLOR, J. F.; REGITANO, L. C. de A.	
Afiliação: 	POLYANA CRISTINE TIZIOTO, FAPESP; LUIZ LEHMANN COUTINHO, USP/ESALQ; G. GASPARIN, USP/ESALQ; WILSON MALAGO JUNIOR, CPPSE; FLAVIA ALINE BRESSANI DONATONI, CPPSE; RYMER RAMIZ TULLIO, CPPSE; RENATA TIEKO NASSU, CPPSE; J. F. TAYLOR, UNIVERSITY OF MISSOURI; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.	
Título: 	Variation in myogenic differentiation 1 mRNA abundance is associated with beef tenderness in Nelore cattle.	
Ano de publicação: 	2016	
Fonte/Imprenta: 	Animal Genetics, v.47, n.4, p. 491-494, aug. 2016.	
Volume: 	47	
Páginas: 	491-494	
DOI: 	10.1111/age.12432	
Idioma: 	Inglês	
Conteúdo: 	The myogenic differentiation 1 gene (MYOD1) has a key role in skeletal muscle differentiation and composition through its regulation of the expression of several muscle-specific genes. We first used a general linear mixed model approach to evaluate the association of MYOD1 expression levels on individual beef tenderness phenotypes. MYOD1 mRNA levels measured by quantitative polymerase chain reactions in 136 Nelore steers were significantly associated (P ? 0.01) with Warner?Bratzler shear force, measured on the longissimus dorsi muscle after 7 and 14 days of beef aging. Transcript abundance for the muscle regulatory gene MYOD1 was lower in animals with more tender beef. We also performed a coexpression network analysis using whole transcriptome sequence data generated from 30 samples of longissimus muscle tissue to identify genes that are potentially regulated by MYOD1. The effect of MYOD1 gene expression on beef tenderness may emerge from its function as an activator of muscle-specific gene transcription such as for the serum response factor (C-fos serum response element-binding transcription factor) gene (SRF), which determines muscle tissue development, composition, growth and maturation.	
Palavras-Chave: 	Expressão gênica; MYOD1; Qualidade da carne; SRF.	
Thesagro: 	Bos Indicus; Gado Nelore.	
Thesaurus Nal: 	Nellore.	
Categoria do assunto: 	G Melhoramento Genético	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CPPSE - (23848-1) - UPC - AP - DD - PROCI-2016.00112 - TIZ - 2016.00156 - DIS