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| Registros recuperados : 55 | |
| 21. |  | REGITANO, L. C. de A.; IBELLI, A. M. G.; GASPARIN, G.; MIYATA, M.; COUTINHO, L. L.; TEODORO, R. L.; MACHADO, M. A.; SILVA, M. V. G. B.; SONSTEGARD, T. S.; ALENCAR, M. M. de. On the search for markers of tick resistance in bovines. In: INTERNATIONAL SYMPOSIUM ON ANIMAL GENOMICS FOR ANIMAL HEALTH, 2007, Paris, FR. Abstracts... Paris: OIE, 2007. p. 20| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 22. | | MIYATA, M.; GASPARIN, G.; COUTINHO, L. L.; MARTINEZ, M. L.; MACHADO, M. A.; SILVA, M. V. G. B. da; CAMPOS, A. L.; SONSTEGARD, T. S.; ROSÁRIO, M. F. do; REGITANO, L. C. de A. Quantitative trait loci (QTL) mapping for growth traits on bovine chromosome 14. Genetics and Molecular Biology, Ribeirão Preto, v. 30, n. 2, p. 364-369, 2007.| Biblioteca(s): Embrapa Gado de Leite; Embrapa Pecuária Sudeste. |
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| 23. | | MYTATA, M.; GASPARIN, G.; COUTINHO, L. L.; MARTINEZ, M. L.; MACHADO, M. A.; SILVA, M. V. G. B. da; CAMPOS, A. L.; SONSTEGARD, T. S.; REGITANO, L. C. de A. Mapeamento de QTLS para peso ao nascimento no cromossomo 14 de bovinos In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 42., 2005, Goiânia. A Produção animal e o foco no agronegócio: anais. Goiânia: SBZ, 2005. 1 CD-ROM.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 24. | | GASPARIN, G.; MIYATA, M.; COUTINHO, M. L.; MARTINEZ, M. L.; TEODORO, R. L.; FURLONG, J.; MACHADO, M. A.; SILVA, M. V. G. B.; SONSTEGARD, T. S.; REGITANO, L. C. de A. Mapping of quantitative trait loci controlling tick [Riphicephalus (Boophilus) microplus] resistance on bovine chromosomes 5, 7, and 14. Animal Genetics, v. 38, n. 5, p. 453-459, oct. 2007.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 25. | | GASPARIN, G.; MIYATA, M.; COUTINHO, L. L.; MARTINEZ, M. L.; TEODORO, R. L.; FURLONG, J.; MACHADO, M. A.; SILVA, M. V. G. B. da; SONSTEGARD, T. S.; REGITANO, L. C. de A. Mapping of quatitative trait loci controlling tick [Riphicephalus (Boophilus) microplus] resistance on bovine chromosomes 5, 7 and 14. Animal Genetics, Oxford, v. 38, n. 5, p. 453-459, 2007.| Biblioteca(s): Embrapa Gado de Leite. |
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| 26. | | SILVA, M. V. G. B.; VERNEQUE, R. da S.; MACHADO, M. A.; PEIXOTO, M. G. C. D.; GUIMARAES, M. F. M.; ARBEX, W. A.; GUEDES, E.; VAN TASSELL, C. P.; SONSTEGARD, T. S. Genome-wide association analysis to identify loci for milk yield in Gyr breed. In: INTERNATIONAL CONFERENCE ON ANIMAL GENETICS, 32., 2010, Edinburgh. Proceedings... Edinburgh: International Society for Animal Genetics, 2010.| Biblioteca(s): Embrapa Gado de Leite. |
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| 27. | | PORTO-NETO, L. R.; SONSTEGARD, T. S.; LIU, G. E.; BICKHART, D. M.; SILVA, M. V. G. B.; MACHADO, M. A.; UTSUNOMIYA, Y. T.; GARCIA, J. F.; GONDRO, C.; VAN TASSELL, C. P. Genomic divergence of zebu and taurine cattle identified through high-density SNP genotyping. BMC Genomics, v. 14, article 876, 2013. Disponível em: http://www.biomedcentral.com/1471-2164/14/876| Biblioteca(s): Embrapa Gado de Leite. |
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| 28. | | MIYATA, M.; GASPARIN, G.; COUTINHO, L. L.; MARTINEZ. M. L.; MACHADO, M. A.; SILVA, M. V. G. B.; CAMPOS, A. L.; SONSTEGARD, T. S.; REGITANO, L. C. de A. Caracterização genética de uma população experimental F2 usando marcadores moleculares no cromossomo 14 ( BTA 14) de bovinos. In: CONGRESSO BRASILEIRO DE GENÉTICA , 51., 2005, Águas de Lindóia. Lindóia: SBG, 2005. p. 364| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 29. | | O'BRIEN, A. M. P.; UTSUNOMIYA, Y. T.; MÉSZÁROS, G.; BICKHART, D. M.; LIU, G. E.; TASSEL, C. P. V.; SONSTEGARD, T. S.; SILVA, M. V. G. B.; GARCIA, J. F.; SÖLKNER, J. Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle. Genetics Selection Evolution, v. 46, n. 19, 2014. 14 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 30. | | GOUVEIA, G. V.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. de A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518-524, oct. 2012.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 31. | | VENERONI-GOUVEIA, G.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518?524, 2011.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 32. | | VENERONI-GOUVEIA, G.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. de A. Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. Animal Genetics, v. 43, n. 5, p. 518-524, nov. 2012.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 33. | | OLIVEIRA, P. S. N.; CESAR, A. S. M.; NASCIMENTO, M. L. do; CHAVES, A. S.; TIZIOTO, P. C.; TULLIO, R. R.; LANNA, D. P. D.; ROSA, A. do N.; SONSTEGARD, T. S.; MOURÃO, G. B.; REECY, J. M.; GARRICK, D. J.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. Identification of genomic regions associated with feed efficiency in Nelore cattle. BMC Genetics, v. 15, n. 1, 2014 10 p.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 34. | | NEVES, H. H.; CARVALHEIRO, R.; O'BRIEN, A. M.; UTSUNOMIYA, Y. T.; CARMO, A. S. do; SCHENKEL, F. S.; SÖLKNER, J.; MCEWAN, J. C.; VAN TASSELL, C. P.; COLE, J. B.; SILVA, M. V. G. B.; QUEIROZ, S. A.; SONSTEGARD, T. S.; GARCIA, J. F. Accuracy of genomic predictions in Bos indicus (Nellore) cattle. Genetics Selection Evolution, v. 46, article 17, 2014.| Biblioteca(s): Embrapa Gado de Leite. |
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| 35. | | REGITANO, L. C. de A.; IBELLI, A. M.; GASPARIN, G.; MIYATA, M.; AZEVEDO, A. L. S.; COUTINHO, L. L.; TEODORO, R. L.; MACHADO, M. A.; SILVA, M. V. G. B.; NAKATA, L. C.; ZAROS, L. G.; SONSTEGARD, T. S.; SILVA, A. M.; ALENCAR, M. M. de; OLIVEIRA, M. C. de S. On the search for markers of tick resistance in bovines. Developments in Biologicals, v. 132, p. 225-230, 2008.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 36. | | REGITANO, L. C. A.; IBELLI, A. M. G.; GASPARIN, G.; MIYATA, M.; AZEVEDO, A. L. S.; COUTINHO, L. L.; TEODORO, R. L.; MACHADO, M. A.; SILVA, M. V. G. B.; NAKATA, L. C.; ZAROS, L. G.; SONSTEGARD, T. S.; SILVA, A. M.; ALENCAR, M. M.; OLIVEIRA, M. C. S. On the search for markers of tick resistance in bovines. In: PINARD, M.; GAY, C.; PASTORET, P.; DODET, B. (Ed.). Animal genomics for animal healt. Basel, Karger: Dev Biol, 2008. p. 225-230. 132| Biblioteca(s): Embrapa Gado de Leite. |
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| 37. | | TIZIOTO, P. C.; TAYLOR, J. F.; DECKER, J. E.; GROMBONI, C. F.; MUDADU, M. de A.; SCHNABEL, R. D.; COUTINHO, L. L.; MOURÃO, G. B.; NASSU, R. T.; DONATONI, F. A. B.; THOLON, P.; SONSTEGARD, T. S.; ALENCAR, M. M. de; TULLIO, R. R.; REECY, J. M.; NOGUEIRA, A. R. de A.; REGITANO, L. C. de A. Effects of quantitative trait loci on iron content of bovine longissimus dorsi muscle. In: WORLD CONGRESS OF GENETICS APPLIED TO LIVESTOK PRODUCTION, 10., 2014, Vancouver. Proceedings... Vancouver: American Society of Animal Science, 2014. 3 p.| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 38. | | UTSUNOMIYA, Y. T.; CARMO, A. S. do; CARVALHEIRO, R.; NEVES, H. H. R.; MATOS, M. C.; ZAVAREZ, L. B.; O'BRIEN, A. M. P.; SÖLKNER, J.; McEWAN, J. C.; COLE, J. B.; TASSEL, C. P. V.; SCHENKEL, F. S.; SILVA, M. V. G. B.; PORTO NETO, L. R.; SONSTEGARD, T. S.; GARCIA, J. F. Genome-wide association study for birth weight in Nellore cattle points to previously described orthologous genes affecting human and bovine height. BMC Genetics, London, v. 14, article 52, 2013.| Biblioteca(s): Embrapa Gado de Leite. |
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| 39. | | UTSUNOMIYA, Y. T.; CARMO, A. S.; NEVES, H. H. R.; CARVALHEIRO, R.; MATOS, M. C.; ZAVAREZ, L. B.; ITO, P. K. R. K.; O'BRIEN, A. M. P.; SOLKNER, J.; PORTO-NETO, L. R.; SCHENKEL, F. S.; McEWAN, J.; COLE, J. B.; SILVA, M. V. G. B.; VAN TASSELL, C. P.; SONSTEGARD, T. S.; GARCIA, J. F. Genome-wide mapping of loci explaining variance in scrotal circumference in Nellore Cattle. Plos One v. 9, n. 2, p. 1-9, 2014.| Biblioteca(s): Embrapa Gado de Leite. |
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| 40. | | SOMAVILLA, A. L.; SONSTEGARD, T. S.; HIGA, R. H.; ROSA, A. do N.; SIQUEIRA, F.; SILVA, L. O. C. da; TORRES JUNIOR, R. A. de A.; COUTINHO, L. L.; MUDADU, M. de A.; ALENCAR, M. M. de; REGITANO, L. C. de A. A genome-wide scan for selection signatures in Nellore cattle. Animal Genetics, v. 45, n. 6, p. 771-781, dec. 2014| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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| Registros recuperados : 55 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
16/01/2014 |
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Data da última atualização: |
09/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PORTO-NETO, L. R.; SONSTEGARD, T. S.; LIU, G. E.; BICKHART, D. M.; SILVA, M. V. G. B.; MACHADO, M. A.; UTSUNOMIYA, Y. T.; GARCIA, J. F.; GONDRO, C.; VAN TASSELL, C. P. |
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Afiliação: |
LAERCIO R. PORTO-NETO, UNIVERSITY OF QUEENSLAND; TAD S. SONSTEGARD, USDA; GEORGE E. LIU, USDA; DEREK M. BICKHART, USDA; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARCO ANTONIO MACHADO, CNPGL; YURI T. UTSUNOMIYA, UNESP; JOSÉ F. GARCIA, UNESP; CEDRIC GONDRO, UNIVERSITY OF NEW ENGLAND; CURTIS P. VAN TASSELL, USDA. |
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Título: |
Genomic divergence of zebu and taurine cattle identified through high-density SNP genotyping. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
BMC Genomics, v. 14, article 876, 2013. |
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DOI: |
https://doi.org/10.1186/1471-2164-14-876 |
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Idioma: |
Inglês |
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Notas: |
Disponível em: http://www.biomedcentral.com/1471-2164/14/876 |
|
Conteúdo: |
Background - Natural selection has molded evolution across all taxa. At an arguable date of around 330,000 years ago there were already at least two different types of cattle that became ancestors of nearly all modern cattle, the Bos taurus taurus more adapted to temperate climates and the tropically adapted Bos taurus indicus. After domestication, human selection exponentially intensified these differences. To better understand the genetic differences between these subspecies and detect genomic regions potentially under divergent selection, animals from the International Bovine HapMap Experiment were genotyped for over 770,000 SNP across the genome and compared using smoothed FST. The taurine sample was represented by ten breeds and the contrasting zebu cohort by three breeds. Results - Each cattle group evidenced similar numbers of polymorphic markers well distributed across the genome. Principal components analyses and unsupervised clustering confirmed the well-characterized main division of domestic cattle. The top 1% smoothed FST, potentially associated to positive selection, contained 48 genomic regions across 17 chromosomes. Nearly half of the top FST signals (n = 22) were previously detected using a lower density SNP assay. Amongst the strongest signals were the BTA7:~50 Mb and BTA14:~25 Mb; both regions harboring candidate genes and different patterns of linkage disequilibrium that potentially represent intrinsic differences between cattle types. The bottom 1% of the smoothed FST values, potentially associated to balancing selection, included 24 regions across 13 chromosomes. These regions often overlap with copy number variants, including the highly variable region at BTA23:~24 Mb that harbors a large number of MHC genes. Under these regions, 318 unique Ensembl genes are annotated with a significant overrepresentation of immune related pathways. Conclusions - Genomic regions that are potentially linked to purifying or balancing selection processes in domestic cattle were identified. These regions are of particular interest to understand the natural and human selective pressures to which these subspecies were exposed to and how the genetic background of these populations evolved in response to environmental challenges and human manipulation. MenosBackground - Natural selection has molded evolution across all taxa. At an arguable date of around 330,000 years ago there were already at least two different types of cattle that became ancestors of nearly all modern cattle, the Bos taurus taurus more adapted to temperate climates and the tropically adapted Bos taurus indicus. After domestication, human selection exponentially intensified these differences. To better understand the genetic differences between these subspecies and detect genomic regions potentially under divergent selection, animals from the International Bovine HapMap Experiment were genotyped for over 770,000 SNP across the genome and compared using smoothed FST. The taurine sample was represented by ten breeds and the contrasting zebu cohort by three breeds. Results - Each cattle group evidenced similar numbers of polymorphic markers well distributed across the genome. Principal components analyses and unsupervised clustering confirmed the well-characterized main division of domestic cattle. The top 1% smoothed FST, potentially associated to positive selection, contained 48 genomic regions across 17 chromosomes. Nearly half of the top FST signals (n = 22) were previously detected using a lower density SNP assay. Amongst the strongest signals were the BTA7:~50 Mb and BTA14:~25 Mb; both regions harboring candidate genes and different patterns of linkage disequilibrium that potentially represent intrinsic differences between cattle types. The bottom 1% of th... Mostrar Tudo |
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Palavras-Chave: |
Bovinos; FST. |
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Thesagro: |
Seleção. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/976438/1/Genomic-divergence-of-zebu-and-taurine-cattle.pdf
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Marc: |
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024 7 $ahttps://doi.org/10.1186/1471-2164-14-876$2DOI
100 1 $aPORTO-NETO, L. R.
245 $aGenomic divergence of zebu and taurine cattle identified through high-density SNP genotyping.$h[electronic resource]
260 $c2013
500 $aDisponível em: http://www.biomedcentral.com/1471-2164/14/876
520 $aBackground - Natural selection has molded evolution across all taxa. At an arguable date of around 330,000 years ago there were already at least two different types of cattle that became ancestors of nearly all modern cattle, the Bos taurus taurus more adapted to temperate climates and the tropically adapted Bos taurus indicus. After domestication, human selection exponentially intensified these differences. To better understand the genetic differences between these subspecies and detect genomic regions potentially under divergent selection, animals from the International Bovine HapMap Experiment were genotyped for over 770,000 SNP across the genome and compared using smoothed FST. The taurine sample was represented by ten breeds and the contrasting zebu cohort by three breeds. Results - Each cattle group evidenced similar numbers of polymorphic markers well distributed across the genome. Principal components analyses and unsupervised clustering confirmed the well-characterized main division of domestic cattle. The top 1% smoothed FST, potentially associated to positive selection, contained 48 genomic regions across 17 chromosomes. Nearly half of the top FST signals (n = 22) were previously detected using a lower density SNP assay. Amongst the strongest signals were the BTA7:~50 Mb and BTA14:~25 Mb; both regions harboring candidate genes and different patterns of linkage disequilibrium that potentially represent intrinsic differences between cattle types. The bottom 1% of the smoothed FST values, potentially associated to balancing selection, included 24 regions across 13 chromosomes. These regions often overlap with copy number variants, including the highly variable region at BTA23:~24 Mb that harbors a large number of MHC genes. Under these regions, 318 unique Ensembl genes are annotated with a significant overrepresentation of immune related pathways. Conclusions - Genomic regions that are potentially linked to purifying or balancing selection processes in domestic cattle were identified. These regions are of particular interest to understand the natural and human selective pressures to which these subspecies were exposed to and how the genetic background of these populations evolved in response to environmental challenges and human manipulation.
650 $aSeleção
653 $aBovinos
653 $aFST
700 1 $aSONSTEGARD, T. S.
700 1 $aLIU, G. E.
700 1 $aBICKHART, D. M.
700 1 $aSILVA, M. V. G. B.
700 1 $aMACHADO, M. A.
700 1 $aUTSUNOMIYA, Y. T.
700 1 $aGARCIA, J. F.
700 1 $aGONDRO, C.
700 1 $aVAN TASSELL, C. P.
773 $tBMC Genomics$gv. 14, article 876, 2013.
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