Data/hora: 02/06/2024 02:18:08

Biblioteca(s): | Embrapa Agroenergia.
Tipo da produção científica: | Artigo em Periódico Indexado
Circulação/Nível: | A - 2
Data corrente: | 18/11/2013
Data da última atualização: | 21/09/2017
Autoria: | CASTRO, A. P. de; SILVA, M. R. S. S. da; QUIRINO, B. F.; KRUGER, R. H.
Afiliação: | Alinne Pereira de Castro, UnB; Maria Regina Silveira Sartori da Silva, UnB; BETANIA FERRAZ QUIRINO, CNPAE; Ricardo Henrique Krüger, UnB.
Título: | Combining "Omics" strategies to analyze the biotechnological potential of complex microbial environments.
Ano de publicação: | 2013
Fonte/Imprenta: | Current Protein and Peptide Science, v. 14, n. 6, 2013.
DOI: | 10.2174/13892037113149990062
Idioma: | Inglês
Conteúdo: | It is well established in the scientific literature that only a small fraction of microorganisms can be cultured by conventional microbiology methods. The ever cheaper and faster DNA sequencing methods, together with advances in bioinformatics, have improved our understanding of the structure and functional behavior of microbial communities in many complex environments. However, the metagenomics approach alone cannot elucidate the functionality of all micro-organisms, because a vast number of potentially new genes have no homologs in public databases. Metatranscriptomics and metaproteomics are approaches based on different techniques and have recently emerged as promising techniques to describe microbial activities within a given environment at the molecular level. In this review, we will discuss current developments and applications of metagenomics, metatranscriptomics and metaproteomics, and their limitations in the study of microbial communities. The combined analysis of genes, mRNA and protein in complex microbial environments will be key to identify novel biological molecules for biotechnological purposes.
Palavras-Chave: | Metagenome; Metaproteome; Metatranscriptome and microbial diversity.
Categoria do assunto: | --
Registro original: | Embrapa Agroenergia (CNPAE)
Exemplares: | CNPAE - (2301-1) - UPC - AP - DD -  -  -  - DIS