Data/hora: 26/09/2024 10:23:23

Biblioteca(s): 	Embrapa Gado de Leite.	
Data corrente: 	12/12/2012	
Data da última atualização: 	09/02/2024	
Autoria: 	DAEMON, E.; MONTEIRO, C. M. O.; MATURANO, R.; SENRA, T. O. S.; CALMON, F.; FAZA, A.; PRATA, M. C. de A.; GEORGOPOULOS, S. L.; OLIVEIRA, L. F. C. DE.	
Afiliação: 	ERIK DAEMON, UFJF; CAIO MATOS DE OLIVEIRA MONTEIRO, UFRRJ; RALPH MATURANO, UFRRJ; TATIANE DE OLIVEIRA SOUZA SENRA, UFJF; FERNANDA CALMON, UFJF; ALINE FAZA, UFJF; MARCIA CRISTINA DE AZEVEDO PRATA, CNPGL; STEFANOS LEITE GEORGOPOULOS, UFJF; LUIZ FERNANDO CAPPA DE OLIVEIRA, UFJF.	
Título: 	Spectroscopic evaluation of thymol dissolved by different methods and influence of acaricidal activity against larvae of rhipicephalus microplus (Acari: ixodidae).	
Ano de publicação: 	2012	
Fonte/Imprenta: 	Parasitology Research, v. 111, n. 5, p. 1901-1906, 2012.	
DOI: 	https://doi.org/10.1007/s00436-012-3033-4	
Idioma: 	Inglês	
Conteúdo: 	The acaricidal activity of three thymol formulations was investigated at five concentrations (1.25, 2.5, 5.0, 7.5, and 10.0 mg/ml) on Rhipicephalus microplus larvae, and the behavior of its solubility in these formulations was analyzed. The thymol was dissolved in distilled water plus 1 % dimethylsulfoxide as adjuvant under two heating regimes (water bath in formulation 1 and hot plate in formulation 2) as well as without heating in 50 % ethanol and 50 % water (v/v). The acaricidal activity was assessed by the modified larval packet test, and the solubilization behavior was investigated by ultraviolet-visible spectroscopy, based on the Beer-Lambert law. With formulations 1 and 2, the mortality was greater than 95 % starting at the thymol concentrations of 5.0 and 7.5 mg/ml, respectively, while with formulation 3, this mortality level was reached starting at a concentration of 2.5 mg/ml, showing that the addition of ethanol in the solution enhanced the acaricidal action of thymol. This result was supported by the LC 90 values, which were 3.3, 2.4, and 1.6 mg/ml of thymol for formulations 1, 2, and 3, respectively. This result is related to the better solubility of thymol in the hydroethanolic formulation, since the spectroscopic analysis revealed that the thymol dissolved more completely in this formulation. This fact was evident once the R (2) obtained from the linear regression analysis of the relation absorbance × concentration of the formulations 1, 2, and 3 approached the optimal value (R (2) = 1) in the following sequence: 1, 2, and 3 (0.717, 0.901, and 0.968, respectively).	
Thesaurus Nal: 	Rhipicephalus microplus.	
Categoria do assunto: 	H Saúde e Patologia	
Registro original: 	Embrapa Gado de Leite (CNPGL)	
Exemplares: 	CNPGL - (19566-1) - UPC - AP - DD -  -  -  - DIS