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| Registros recuperados : 568 | |
| 13. |  | SÓSA-GOMEZ, D. R. A diversidade de vírus como fonte de ativos para empresas produtoras de agentes de controle microbiano. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 28., 2022, Fortaleza. Biodiversidade: Conhecer, conservar e utilizar. anais. Fortaleza: Sociedade Entomológica do Brasil, 2022. Edição Técnica: Nivia da Silva Dias Pini, Gerane Celly Dias Bezerra Silva, Márcio Alves Silva, Regiane Cristina Oliveira, José Wagner da Silva Melo, Flávia Rabelo Barbosa. resumo. p. 1057.| Biblioteca(s): Embrapa Soja. |
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Registro Completo
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Biblioteca(s): |
Embrapa Soja. |
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Data corrente: |
13/06/2016 |
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Data da última atualização: |
19/06/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
ARDISSON-ARAÚJO, D. M. P.; LIMA, R. N.; MELO, F. L.; CLEM, R. J.; HUANG, N.; BÁO, S. N.; SOSA-GÓMEZ, D. R.; RIBEIRO, B. M. |
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Afiliação: |
DANIEL M. P. ARDISSON-ARAÚJO, UNB; RAYANE NUNES LIMA, UNB; FERNANDO L. MELO, UNB; ROLLIE J. CLEM, KANSAS STATE UNIVERSITY; NING HUANG, Kansas State University; SÔNIA NAIR BÁO, UNB; DANIEL RICARDO SOSA GOMEZ, CNPSO; BERGMANN M. RIBEIRO, UNB. |
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Título: |
Genome sequence of Perigonia lusca single nucleopolyhedrovirus: insights into the evolution of a nucleotide metabolism enzyme in the family Baculoviridae. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Scientific Reports, v. 6, n. 24612, jun. 2016. |
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ISSN: |
2045-2322 |
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DOI: |
10.1038/srep24612 |
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Idioma: |
Inglês |
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Conteúdo: |
The genome of a novel group II alphabaculovirus, Perigonia lusca single nucleopolyhedrovirus (PeluSNPV), was sequenced and shown to contain 132,831bp with 145 putative ORFs (open reading frames) of at least 50 amino acids. An interesting feature of this novel genome was the presence of a putative nucleotide metabolism enzyme-encoding gene (pelu112). The pelu112 gene was predicted to encode a fusion of thymidylate kinase (tmk) and dUTP diphosphatase (dut). Phylogenetic analysis indicated that baculoviruses have independently acquired tmk and dut several times during their evolution. Two homologs of the tmk-dut fusion gene were separately introduced into the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) genome, which lacks tmk and dut. The recombinant baculoviruses produced viral DNA, virus progeny, and some viral proteins earlier during in vitro infection and the yields of viral occlusion bodies were increased 2.5-fold when compared to the parental virus. Interestingly, both enzymes appear to retain their active sites, based on separate modeling using previously solved crystal structures. We suggest that the retention of these tmk-dut fusion genes by certain baculoviruses could be related to accelerating virus replication and to protecting the virus genome from deleterious mutation. |
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Thesagro: |
Baculovirus; Genoma; Virus. |
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Thesaurus NAL: |
Baculoviridae; Genome assembly. |
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Categoria do assunto: |
S Ciências Biológicas |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/144282/1/Genome-sequence-of-Perigonia-lusca-2016.pdf
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Marc: |
LEADER 02182naa a2200289 a 4500
001 2046809
005 2017-06-19
008 2016 bl uuuu u00u1 u #d
022 $a2045-2322
024 7 $a10.1038/srep24612$2DOI
100 1 $aARDISSON-ARAÚJO, D. M. P.
245 $aGenome sequence of Perigonia lusca single nucleopolyhedrovirus$binsights into the evolution of a nucleotide metabolism enzyme in the family Baculoviridae.$h[electronic resource]
260 $c2016
520 $aThe genome of a novel group II alphabaculovirus, Perigonia lusca single nucleopolyhedrovirus (PeluSNPV), was sequenced and shown to contain 132,831bp with 145 putative ORFs (open reading frames) of at least 50 amino acids. An interesting feature of this novel genome was the presence of a putative nucleotide metabolism enzyme-encoding gene (pelu112). The pelu112 gene was predicted to encode a fusion of thymidylate kinase (tmk) and dUTP diphosphatase (dut). Phylogenetic analysis indicated that baculoviruses have independently acquired tmk and dut several times during their evolution. Two homologs of the tmk-dut fusion gene were separately introduced into the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) genome, which lacks tmk and dut. The recombinant baculoviruses produced viral DNA, virus progeny, and some viral proteins earlier during in vitro infection and the yields of viral occlusion bodies were increased 2.5-fold when compared to the parental virus. Interestingly, both enzymes appear to retain their active sites, based on separate modeling using previously solved crystal structures. We suggest that the retention of these tmk-dut fusion genes by certain baculoviruses could be related to accelerating virus replication and to protecting the virus genome from deleterious mutation.
650 $aBaculoviridae
650 $aGenome assembly
650 $aBaculovirus
650 $aGenoma
650 $aVirus
700 1 $aLIMA, R. N.
700 1 $aMELO, F. L.
700 1 $aCLEM, R. J.
700 1 $aHUANG, N.
700 1 $aBÁO, S. N.
700 1 $aSOSA-GÓMEZ, D. R.
700 1 $aRIBEIRO, B. M.
773 $tScientific Reports$gv. 6, n. 24612, jun. 2016.
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Embrapa Soja (CNPSO) |
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