Data/hora: 17/06/2024 09:33:45

Biblioteca(s): | Embrapa Agroindústria de Alimentos.
Tipo da produção científica: | Artigo em Periódico Indexado
Circulação/Nível: | A - 2
Data corrente: | 27/06/2013
Data da última atualização: | 29/02/2016
Autoria: | KAIPPERT, V. C.; UEHARA, S. K.; D'ANDREA, C. L.; NOGUEIRA, J.; LAGO, M. F. do; LOPES, M. C. O. dos S.; OLIVEIRA, E. M. M.; ROSADO, E. L.
Afiliação: | VANESSA CHAIA KAIPPERT, UFRJ; SOFIA KIMI UEHARA, UFRJ; CARLA LIMA D'ANDREA, UFRJ; JULIANA NOGUEIRA, UFRJ; MÁRCIA FÓFANO DO LAGO, UFRJ; MARCELLY CUNHA OLIVEIRA DOS SANTOS, UFRJ; EDNA MARIA MORAIS OLIVEIRA, CTAA; ELIANE LOPES ROSADO, UFRJ.
Título: | Influence of the body mass and visceral adiposity on glucose metabolism in obese women with Pro12Pro genotype in PPARgamma2 gene.
Ano de publicação: | 2013
Fonte/Imprenta: | Nutrición Hospitalaria, Madrid, v. 28, n. 3, p. 694-700, 2013.
DOI: | 10.3305/nh.2013.28.3.6372
Idioma: | Inglês
Conteúdo: | Introduction: Glucose metabolism may be altered in obesity and genotype for PPAR 2 can influence this variable. Objective: To evaluate the influence of body mass (BM) and visceral adiposity (VA) in glucose metabolism in morbid obese women with Pro12Pro genotype. Methods: Were selected 25 morbidly obese women. Groups were formed according to body mass index (BMI) [G1: 40-45 kg/m2 (n = 17); G2: > 45 kg/m2 (n = 8)]. Anthropometric, glycemia and insulinemia assessments (fasting, 60 and 120 minutes after high polyunsaturated fatty acids meal) were carried out. The insulin resistance (IR) and insulin sensitivity (IS) were assessed by HOMA-IR and QUICKI respectively. Results: G2 had higher BMI and waist circumference, compared to G1, impaired fasting glucose, low IS and higher IR. The postprandial glucose was normal, but there was a higher insulin peak one hour after the meal in G2. Conclusion: Increased BM and VA were associated with worse glucose metabolism suggesting metabolic differences between morbid obese with Pro12Pro genotype.
Palavras-Chave: | Índice de massa corporal; Metabolismo da glicose; PPARgamma; Resistência à insulina.
Thesagro: | Obesidade.
Categoria do assunto: | X Pesquisa, Tecnologia e Engenharia
URL: | http://ainfo.cnptia.embrapa.br/digital/bitstream/item/84902/1/2013-005.pdf
Registro original: | Embrapa Agroindústria de Alimentos (CTAA)
Exemplares: | CTAA - (11817-1) - UPC - AP - PP - 2013/005 -  - 2013.00005 - DIS