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Registros recuperados : 104 | |
8. | | OLIVEIRA, J. A. da S.; QUINTAO, C. C. R.; ASCARI, I. J.; CAMARGO, L. S. de A. Efeito da técnica de biópsia no desenvolvimento de embriões bovinos produzidos in vitro. In: WORKSHOP DE INICIAÇÃO CIENTÍFICA DA EMBRAPA GADO DE LEITE, 16., 2015, Juiz de Fora, MG Anais... Juiz de Fora: Embrapa Gado de Leite, 2015. 1 CD-ROM. (Embrapa Gado de Leite. Documentos, 185.). 2 p. Biblioteca(s): Embrapa Gado de Leite. |
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9. | | QUINTAO, C. C. R.; OLIVEIRA, C. S.; PEREIRA, M. M.; CAMARGO, L. S. de A.; SARAIVA, N. Z. Effects of forskolin supplementation at different stages of IVP on the preimplantation development of bovine embryos. Animal Reproduction, v. 19, n. 2, e22149, 2022. Edição dos abstracts da Annual Meeting of the Brazilian Embryo Technology Society, 35., Foz do Iguaçu, 2022. Biblioteca(s): Embrapa Gado de Leite. |
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15. | | QUINTAO, C. C. R.; SARAIVA, N. Z.; OLIVEIRA, C. S.; CAMARGO, L. S. de A.; MUNK, M. Zinc oxide nanoparticles supplementation on in vitro maturation of bovine oocytes and its effects on the embryo quality, lipid accumulation, and preimplantation development. Animal Reproduction, v. 20, n. 2, 2023. Abstracts of 36th Annual Meeting of the Brazilian Embryo Technology Society (SBTE). Biblioteca(s): Embrapa Gado de Leite. |
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16. | | QUINTÃO, C. C. R.; SERAPIÃO, R. V.; SINGULANI, J. DE L.; RAPOSO, N. R. B.; CAMARGO, L. S. de A.; VIANA, J. H. M. Citotoxicidade de Lippia Lacunosa e Lippia Rotundifolia em fibroblastos bovinos por diferentes métodos. In: REUNIÃO ANUAL DA FEDERAÇÃO DE SOCIEDADE DE BIOLOGIA EXPERIMENTAL, 24., 2009, Águas de Lindóia. Anais... Águas de Lindóia: FESBE, 2009. Biblioteca(s): Embrapa Gado de Leite. |
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17. | | QUINTAO, C. C. R.; ALMEIDA, C. G. de; SOUZA, G. T.; LADEIRA, L. O.; BRANDAO, H. de M.; CAMARGO, L. S. de A.; MUNK, M. Complexação da proteína CAS9 e RNA-GUIA com nanotubos de carbono visando edição gênica em células e embriões de mamíferos. In: SIMPÓSIO NACIONAL DE NANOBIOTECNOLOGIA, 2., 2019, São Bernardo do Campo. Livro de resumos. Santo André: Universidade Federal do ABC, 2018. Biblioteca(s): Embrapa Gado de Leite. |
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18. | | OLIVEIRA, C. S.; CAMARGO, L. S. de A.; SILVA, M. V. G. B.; SARAIVA, N. Z.; QUINTAO, C. C. R.; MACHADO, M. A. Embryo biopsies for genomic selection in tropical dairy cattle. Animal Reproduction, v. 20, n. 2, e20230064, 2023. Biblioteca(s): Embrapa Gado de Leite. |
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19. | | CAMARGO, L. S. de A.; QUINTAO, C. C. R.; DENICOL, A. C.; IGUMA, L. T.; CARVALHO, B. C. de; SIQUEIRA, L. G. B.; VIANA, J. H. M. Efeito da tricostatina A na produção de embriões bovinos por transferência nuclear com células somáticas e subsequente gestações. Reunião Anual da Sociedade Brasileira de Tecnologia de Embriões, 25., 2011, Cumbuco. Resumos... p. 436 Biblioteca(s): Embrapa Gado de Leite. |
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20. | | ASCARI, I. J.; ALVES, N. G.; CAMARGO, L. S. de A.; JASMIN, J.; QUINTAO, C. C. R.; OLIVEIRA, J. A. S.; ARAÚJO, T. D. Effect of melatonin on DNA fragmentation and in vitro maturation of bovine oocytes subjected to heat shock Animal Reproduction., v.12, n.3, Jul./Sept. 2015. Edição dos proceedings do 29º Annual Meeting of the Brazilian Embryo Technology Society, 2015, Gramado. Biblioteca(s): Embrapa Gado de Leite. |
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Registros recuperados : 104 | |
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Registro Completo
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
10/05/2022 |
Data da última atualização: |
10/05/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
QUINTAO, C. C. R.; CAMARGO, L. S. de A.; BRANDAO, H. de M.; SARAIVA, N. Z.; MUNK, M. |
Afiliação: |
CAROLINA CAPOBIANGO ROMANO QUINTAO, CNPGL; LUIZ SERGIO DE ALMEIDA CAMARGO, CNPGL; HUMBERTO DE MELLO BRANDAO, CNPGL; NAIARA ZOCCAL SARAIVA, CNPGL; MICHELE MUNK, Universidade Federal de Juiz de Fora. |
Título: |
Challenges in the use of nanostructures as carriers of nucleic acids in clinical practice. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Einstein, v. 20, eRB5898, 2022. |
DOI: |
https://doi.org/10.31744/einstein_journal/2022RB5898 |
Idioma: |
Inglês |
Conteúdo: |
The delivery of nucleic acids to cells is considered a crucial step for the success of genetic modifications aimed at therapeutic purposes or production of genetically modified animals. In this context, nanotechnology is one of the most promising fields of science, with the potential to solve several existing problems. Nanostructures have desirable characteristics to be used as carriers, such as nanometric size, large surface area, cell internalization capacity, prolonged and controlled release, among others. Genetically modified animals can contribute to the production of biopharmaceuticals, through the expression of high-associated-value molecules. The production of these animals, also known as biofactories, further enhances Brazilian agribusiness, since it allows adding value to the final product, and favors the integration between the agricultural market and the pharmaceutical sector. However, there is a growing concern about the safety and possible harmful effects of nanostructures, since data on the safe use of these materials are still insufficient. The objective of this review was to address aspects of the use of nanostructures, mainly carbon nanotubes as nucleic acid carriers, aiming at the production of genetically modified animals, with the certainty that progress in this field of knowledge depends on more information on the mechanisms of interaction between nanostructures, cells and embryos, as well as on its toxicity. |
Palavras-Chave: |
Genetically modified; Nanoestrutura; Nanotecnologia; Nanotubo de carbono. |
Thesagro: |
Ácido Nucléico; Genética Animal; Melhoramento Genético Animal. |
Thesaurus NAL: |
Embryonic structures; Nanotubes; Nucleic acids. |
Categoria do assunto: |
G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1142832/1/Challenges-use-nanostructures.pdf
|
Marc: |
LEADER 02366naa a2200301 a 4500 001 2142832 005 2022-05-10 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.31744/einstein_journal/2022RB5898$2DOI 100 1 $aQUINTAO, C. C. R. 245 $aChallenges in the use of nanostructures as carriers of nucleic acids in clinical practice.$h[electronic resource] 260 $c2022 520 $aThe delivery of nucleic acids to cells is considered a crucial step for the success of genetic modifications aimed at therapeutic purposes or production of genetically modified animals. In this context, nanotechnology is one of the most promising fields of science, with the potential to solve several existing problems. Nanostructures have desirable characteristics to be used as carriers, such as nanometric size, large surface area, cell internalization capacity, prolonged and controlled release, among others. Genetically modified animals can contribute to the production of biopharmaceuticals, through the expression of high-associated-value molecules. The production of these animals, also known as biofactories, further enhances Brazilian agribusiness, since it allows adding value to the final product, and favors the integration between the agricultural market and the pharmaceutical sector. However, there is a growing concern about the safety and possible harmful effects of nanostructures, since data on the safe use of these materials are still insufficient. The objective of this review was to address aspects of the use of nanostructures, mainly carbon nanotubes as nucleic acid carriers, aiming at the production of genetically modified animals, with the certainty that progress in this field of knowledge depends on more information on the mechanisms of interaction between nanostructures, cells and embryos, as well as on its toxicity. 650 $aEmbryonic structures 650 $aNanotubes 650 $aNucleic acids 650 $aÁcido Nucléico 650 $aGenética Animal 650 $aMelhoramento Genético Animal 653 $aGenetically modified 653 $aNanoestrutura 653 $aNanotecnologia 653 $aNanotubo de carbono 700 1 $aCAMARGO, L. S. de A. 700 1 $aBRANDAO, H. de M. 700 1 $aSARAIVA, N. Z. 700 1 $aMUNK, M. 773 $tEinstein$gv. 20, eRB5898, 2022.
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