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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
10/04/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
REGATIERI, I. C.; URI, R. A.; FERRAZ, G. de C.; QUEIROZ-NETO, A. de. |
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Afiliação: |
INAÊ CRISTINA REGATIERI, FCAV/UNESP; ROGÉRIO ABDALLAH CURI, FMVZ/UNESP; GUILHERME DE CAMARGO FERRAZ, FCAV/UNESP; ANTNIO DE QUEIROZ-NETO, FCAV/UNESP. |
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Título: |
Candidate genes for performance in horses, including monocarboxylate transporters. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 1, p. 66-72, janeiro. 2017. |
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Idioma: |
Inglês |
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Conteúdo: |
Some horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits controlling ovement in vertebrates and may be associated with gait performance in horses. This review describes how the monocarboxylate transporters work during physical exercise in athletic horses and the influence of polymorphisms in candidate genes for athletic performance in horses. MenosSome horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits... Mostrar Tudo |
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Palavras-Chave: |
Fatigue; Monocarboxylate transporters; Polymorphisms. |
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Thesaurus Nal: |
Genes; Horses; Lactates. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/158785/1/Candidate-genes-for-performance-in-horses.pdf
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Marc: |
LEADER 02449naa a2200229 a 4500
001 2068271
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aREGATIERI, I. C.
245 $aCandidate genes for performance in horses, including monocarboxylate transporters.
260 $c2017
520 $aSome horse breeds are highly selected for athletic activities. The athletic potential of each animal can be measured by its performance in sports. High athletic performance depends on the animal capacity to produce energy through aerobic and anaerobic metabolic pathways, among other factors. Transmembrane proteins called monocarboxylate transporters, mainly the isoform 1 (MCT1) and its ancillary protein CD147, can help the organism to adapt to physiological stress caused by physical exercise, transporting lactate and H+ ions. Horse breeds are selected for different purposes so we might expect differences in the amount of those proteins and in the genotypic frequencies for genes that play a significant role in the performance of the animals. The study of MCT1 and CD147 gene polymorphisms, which can affect the formation of the proteins and transport of lactate and H+, can provide enough information to be used for selection of athletic horses increasingly resistant to intense exercise. Two other candidate genes, the PDK4 and DMRT3, have been associated with athletic potential and indicated as possible markers for performance in horses. The oxidation of fatty acids is highly effective in generating ATP and is controlled by the expression of PDK4 (pyruvate dehydrogenase kinase, isozyme 4) in skeletal muscle during and after exercise. The doublesex and mab-3 related transcription factor 3 (DMRT3) gene encodes an important transcription factor in the setting of spinal cord circuits controlling ovement in vertebrates and may be associated with gait performance in horses. This review describes how the monocarboxylate transporters work during physical exercise in athletic horses and the influence of polymorphisms in candidate genes for athletic performance in horses.
650 $aGenes
650 $aHorses
650 $aLactates
653 $aFatigue
653 $aMonocarboxylate transporters
653 $aPolymorphisms
700 1 $aURI, R. A.
700 1 $aFERRAZ, G. de C.
700 1 $aQUEIROZ-NETO, A. de.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 1, p. 66-72, janeiro. 2017.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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Registro Completo
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
25/09/1998 |
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Data da última atualização: |
13/07/2018 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
SANTOS, M. X. dos; PARENTONI, S. N.; GUIMARAES, P. E. de O.; GAMA, E. E. G.; PACHECO, C. A. P.; VIEIRA JUNIOR, P. A.; WINKLER, E. I.; SOUZA, I. R. P. de; MEIRELLES, W. F. |
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Afiliação: |
EMBRAPA-CNPMS; SIDNEY NETTO PARENTONI, CNPMS; PAULO EVARISTO DE O GUIMARAES, CNPMS. |
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Título: |
Seleção e desenvolvimento do composto de milho Vega Precoce (CMS 50) para a região Sul. |
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Ano de publicação: |
1998 |
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Fonte/Imprenta: |
In: CONGRESSO NACIONAL DE MILHO E SORGO, 22., 1998, Recife. Globalização e segurança alimentar: anais. Recife: IPA, 1998. |
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Descrição Física: |
1 CD-ROM. |
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Idioma: |
Português |
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Palavras-Chave: |
Brasil; Maize; South; Sul. |
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Thesagro: |
Melhoramento; Milho; Variedade; Zea Mays. |
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Thesaurus NAL: |
Brazil; breeding; varieties. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/39214/1/Selecao-desenvolvimento.pdf
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Marc: |
LEADER 00988nam a2200337 a 4500
001 1480607
005 2018-07-13
008 1998 bl uuuu u00u1 u #d
100 1 $aSANTOS, M. X. dos
245 $aSeleção e desenvolvimento do composto de milho Vega Precoce (CMS 50) para a região Sul.$h[electronic resource]
260 $aIn: CONGRESSO NACIONAL DE MILHO E SORGO, 22., 1998, Recife. Globalização e segurança alimentar: anais. Recife: IPA$c1998
300 $c1 CD-ROM.
650 $aBrazil
650 $abreeding
650 $avarieties
650 $aMelhoramento
650 $aMilho
650 $aVariedade
650 $aZea Mays
653 $aBrasil
653 $aMaize
653 $aSouth
653 $aSul
700 1 $aPARENTONI, S. N.
700 1 $aGUIMARAES, P. E. de O.
700 1 $aGAMA, E. E. G.
700 1 $aPACHECO, C. A. P.
700 1 $aVIEIRA JUNIOR, P. A.
700 1 $aWINKLER, E. I.
700 1 $aSOUZA, I. R. P. de
700 1 $aMEIRELLES, W. F.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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