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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
27/06/2013 |
Data da última atualização: |
29/02/2016 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
KAIPPERT, V. C.; UEHARA, S. K.; D'ANDREA, C. L.; NOGUEIRA, J.; LAGO, M. F. do; LOPES, M. C. O. dos S.; OLIVEIRA, E. M. M.; ROSADO, E. L. |
Afiliação: |
VANESSA CHAIA KAIPPERT, UFRJ; SOFIA KIMI UEHARA, UFRJ; CARLA LIMA D'ANDREA, UFRJ; JULIANA NOGUEIRA, UFRJ; MÁRCIA FÓFANO DO LAGO, UFRJ; MARCELLY CUNHA OLIVEIRA DOS SANTOS, UFRJ; EDNA MARIA MORAIS OLIVEIRA, CTAA; ELIANE LOPES ROSADO, UFRJ. |
Título: |
Influence of the body mass and visceral adiposity on glucose metabolism in obese women with Pro12Pro genotype in PPARgamma2 gene. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Nutrición Hospitalaria, Madrid, v. 28, n. 3, p. 694-700, 2013. |
DOI: |
10.3305/nh.2013.28.3.6372 |
Idioma: |
Inglês |
Conteúdo: |
Introduction: Glucose metabolism may be altered in obesity and genotype for PPAR 2 can influence this variable. Objective: To evaluate the influence of body mass (BM) and visceral adiposity (VA) in glucose metabolism in morbid obese women with Pro12Pro genotype. Methods: Were selected 25 morbidly obese women. Groups were formed according to body mass index (BMI) [G1: 40-45 kg/m2 (n = 17); G2: > 45 kg/m2 (n = 8)]. Anthropometric, glycemia and insulinemia assessments (fasting, 60 and 120 minutes after high polyunsaturated fatty acids meal) were carried out. The insulin resistance (IR) and insulin sensitivity (IS) were assessed by HOMA-IR and QUICKI respectively. Results: G2 had higher BMI and waist circumference, compared to G1, impaired fasting glucose, low IS and higher IR. The postprandial glucose was normal, but there was a higher insulin peak one hour after the meal in G2. Conclusion: Increased BM and VA were associated with worse glucose metabolism suggesting metabolic differences between morbid obese with Pro12Pro genotype. |
Palavras-Chave: |
Índice de massa corporal; Metabolismo da glicose; PPARgamma; Resistência à insulina. |
Thesagro: |
Obesidade. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/84902/1/2013-005.pdf
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Marc: |
LEADER 01911naa a2200277 a 4500 001 1960737 005 2016-02-29 008 2013 bl uuuu u00u1 u #d 024 7 $a10.3305/nh.2013.28.3.6372$2DOI 100 1 $aKAIPPERT, V. C. 245 $aInfluence of the body mass and visceral adiposity on glucose metabolism in obese women with Pro12Pro genotype in PPARgamma2 gene. 260 $c2013 520 $aIntroduction: Glucose metabolism may be altered in obesity and genotype for PPAR 2 can influence this variable. Objective: To evaluate the influence of body mass (BM) and visceral adiposity (VA) in glucose metabolism in morbid obese women with Pro12Pro genotype. Methods: Were selected 25 morbidly obese women. Groups were formed according to body mass index (BMI) [G1: 40-45 kg/m2 (n = 17); G2: > 45 kg/m2 (n = 8)]. Anthropometric, glycemia and insulinemia assessments (fasting, 60 and 120 minutes after high polyunsaturated fatty acids meal) were carried out. The insulin resistance (IR) and insulin sensitivity (IS) were assessed by HOMA-IR and QUICKI respectively. Results: G2 had higher BMI and waist circumference, compared to G1, impaired fasting glucose, low IS and higher IR. The postprandial glucose was normal, but there was a higher insulin peak one hour after the meal in G2. Conclusion: Increased BM and VA were associated with worse glucose metabolism suggesting metabolic differences between morbid obese with Pro12Pro genotype. 650 $aObesidade 653 $aÍndice de massa corporal 653 $aMetabolismo da glicose 653 $aPPARgamma 653 $aResistência à insulina 700 1 $aUEHARA, S. K. 700 1 $aD'ANDREA, C. L. 700 1 $aNOGUEIRA, J. 700 1 $aLAGO, M. F. do 700 1 $aLOPES, M. C. O. dos S. 700 1 $aOLIVEIRA, E. M. M. 700 1 $aROSADO, E. L. 773 $tNutrición Hospitalaria, Madrid$gv. 28, n. 3, p. 694-700, 2013.
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Embrapa Agroindústria de Alimentos (CTAA) |
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