Data/hora: 25/06/2024 13:36:12

Biblioteca(s): 	Embrapa Pecuária Sudeste; Embrapa Suínos e Aves.	
Data corrente: 	24/05/2024	
Data da última atualização: 	27/05/2024	
Autoria: 	SALMÓRIA, L. A.; IBELLI, A. M. G.; TAVERNARI, F. de C.; PEIXOTO, J. de O.; MORES, M. A. Z.; MARCELINO, D. E. P.; PINTO, K. D. S.; COLDEBELLA, A.; SUREK, D.; KAWSKI, V. L.; LEDUR, M. C.	
Afiliação: 	LETÍCIA ALVES SALMÓRIA, UNIVERSIDADE ESTADUAL DO CENTRO-OESTE; ADRIANA MERCIA GUARATINI IBELLI, CPPSE; FERNANDO DE CASTRO TAVERNARI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; DÉBORA ESTER PETRY MARCELINO, FACULDADE DE CONCÓRDIA; KARINE DAENQUELE SILVA PINTO, UNIVERSIDADE FEDERAL DE SÃO JOÃO DEL REI; ARLEI COLDEBELLA, CNPSA; DIEGO SUREK, GGPJ; VICKY LILGE KAWSKI, CNPSA; MONICA CORREA LEDUR, CNPSA.	
Título: 	CYP24A1 and TRPC3 gene expression in kidneys and their involvement in calcium and phosphate metabolism in laying hens.	
Ano de publicação: 	2024	
Fonte/Imprenta: 	Animals, v. 14, n. 1407, 2024.	
DOI: 	https://doi.org/10.3390/ani14101407	
Idioma: 	Inglês	
Conteúdo: 	Ca and P homeostasis across the egg-laying cycle is a complex process involving absorption in the small intestine, reabsorption/excretion in the kidneys, and eggshell gland secretion. Diets with inadequate calcium and phosphorus can interfere with their absorption and digestibility, resulting in eggshell quality losses and reduced productive life, affecting egg production and welfare. A better understanding of gene expression profiles in the kidneys of laying hens during the late egg-laying period could clarify the renal role in mineral metabolism at this late stage. Therefore, the performance, egg quality and bone integrity-related traits, and expression profiles of kidney candidate genes were evaluated in 73-week-old laying hens receiving different Ca and P ratios in their diet: a high Ca/P ratio (HR, 22.43), a low ratio (LR, 6.71), and a medium ratio (MR, 11.43). The laying hens receiving the HR diet had improved egg production and eggshell quality traits compared to the other two groups. Humerus length was shorter in the HR than in the other groups. The CYP24A1 and TRPC3 genes were differentially expressed (p.adj ≤ 0.05) among the groups. Therefore, their expression profiles could be involved in calcium and phosphate transcellular transport in 73-week-old laying hens as a way to keep mineral absorption at adequate levels.	
Palavras-Chave: 	Expressão gênica; QPCR; Qualidade de ovos; Reação em cadeia da polimerase quantitativa.	
Thesagro: 	Cálcio; Galinha Para Postura; Mineral; Poedeira Comercial; Rim; Saúde.	
Thesaurus Nal: 	Chickens; Egg quality; Quantitative polymerase chain reaction.	
Categoria do assunto: 	--
X Pesquisa, Tecnologia e Engenharia	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1164461/1/CYP24A1andTRPC3.pdf
http://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1164453/1/final9864-CYP24A1-and-TRPC3-gene-expression-tavernari.pdf	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CNPSA - (22663-1) - UPC - AP - DD -  -  -  - DIS
CPPSE - (26384-1) - UPC - AP - DD - PROCI-2024.00033 - SAL - 2024.00079 - DIS