Data/hora: 12/06/2024 12:43:59

Biblioteca(s): | Embrapa Pecuária Sudeste.
Data corrente: | 17/11/2020
Data da última atualização: | 17/11/2020
Autoria: | COLNAGO, L. A.; TREVISOL, I. M.; RECH, D. V.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H.
Afiliação: | LUIZ ALBERTO COLNAGO, CNPDIA; IARA MARIA TREVISOL, CNPSA; DAIANE VOSS RECH, CNPSA; LUCIMARA APARECIDA FORATO, CNPDIA; CIRLEI IGREJA DO NASCIMENTO MITRE, USP; JOSÉ PAULO GAGLIARDI LEITE, FIOCRUZ; RODRIGO GIGLIOTI, IZ; CINTIA HIROMI OKINO, CPPSE.
Título: | Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge.
Ano de publicação: | 2020
Fonte/Imprenta: | International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020.
Páginas: | 1 - 9
DOI: | 10.3390/ijerph17186456
Idioma: | Inglês

Conteúdo:

The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and ecient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus ecacy of the proposed films. Polystyrene petri dishes were covered with a thin
layer of detergent formula. After drying, the films were exposed to dierent virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19.

Palavras-Chave: | Antiviral; Coronavirus; Detergent; Film; Sanitization; Virucide.
Categoria do assunto: | H Saúde e Patologia
Registro original: | Embrapa Pecuária Sudeste (CPPSE)
Exemplares: | CPPSE - (25152-1) - UPC - AP - DD - PROCI-2020.00067 - COL - 2020.00118 - DIS