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Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
08/09/2020 |
Data da última atualização: |
10/09/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. |
Afiliação: |
JULIANA AFONSO, UFSCar; MARINA RUFINO SALINAS FORTES, The University of Queensland; ANTONIO REVERTER, Agriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Brisbane; WELLISON JARLES DA SILVA DINIZ, UFSCar; ALINE SILVA MELLO CESAR, Esalq/USP; ANDRESSA OLIVEIRA DE LIMA, UFSCar; JULIANA PETRINI, UNIFAL; MARCELA M. DE SOUZA, Iowa State University; LUIZ LEHMANN COUTINHO, Esalq/USP; GERSON BARRETO MOURÃO, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; CAIO FERNANDO GROMBONI, Bahia Federal Institute of Education, Science and Technology, Ilhéus; ANA RITA ARAÚJO NOGUEIRA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Scientific Reports, v. 10, n. 1, p. 1-16, 2020 |
DOI: |
https://doi.org/10.1038/s41598-020-65454-7 |
Idioma: |
Inglês |
Notas: |
Article: 8436. |
Conteúdo: |
Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. MenosMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators describe... Mostrar Tudo |
Palavras-Chave: |
Expressão gênica. |
Thesagro: |
Bos Indicus; Gado Nelore. |
Thesaurus Nal: |
Cattle; Gene expression. |
Categoria do assunto: |
-- G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/215819/1/AP-Genetic-regulators-2020.pdf
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Marc: |
LEADER 02716naa a2200361 a 4500 001 2124802 005 2020-09-10 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1038/s41598-020-65454-7$2DOI 100 1 $aAFONSO, J. 245 $aGenetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach.$h[electronic resource] 260 $c2020 500 $aArticle: 8436. 520 $aMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. 650 $aCattle 650 $aGene expression 650 $aBos Indicus 650 $aGado Nelore 653 $aExpressão gênica 700 1 $aFORTES, M. R. S. 700 1 $aREVERTER, A. 700 1 $aDINIZ, W. J. da S. 700 1 $aCESAR, A. S. M. 700 1 $aLIMA, A. O. de 700 1 $aPETRINI, J. 700 1 $aSOUZA, M. de S. 700 1 $aCOUTINHO, L. L. 700 1 $aMOURÃO, G. B. 700 1 $aZERLOTINI NETO, A. 700 1 $aGROMBONI, C. F. 700 1 $aNOGUEIRA, A. R. A. 700 1 $aREGITANO, L. C. de A. 773 $tScientific Reports$gv. 10, n. 1, p. 1-16, 2020
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Embrapa Agricultura Digital (CNPTIA) |
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Biblioteca(s): |
Embrapa Acre. |
Data corrente: |
02/04/2018 |
Data da última atualização: |
16/11/2023 |
Tipo da produção científica: |
Resumo em Anais de Congresso |
Autoria: |
SANTOS, C. F. dos; MIQUELONI, D. P.; ASSIS, G. M. L. de. |
Afiliação: |
Cléia Florentino dos Santos; Daniela Popim Miqueloni, Universidade Federal do Acre (Ufac); GISELLE MARIANO LESSA DE ASSIS, CPAF-Acre. |
Título: |
Ângulo de inclinação da folha de amendoim forrageiro na época seca. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
In: SEMINÁRIO DE INICIAÇÃO CIENTÍFICA DA UFAC, 26., 2017, Rio Branco. Anais... Rio Branco: Ufac, 2018. |
Páginas: |
p. 512. |
ISBN: |
978-85-8236-078-1 |
Idioma: |
Português |
Conteúdo: |
A menor interceptação da radiação solar, oriunda do aumento do ângulo da folha em relação ao solo, tendendo à posição vertical, pode minimizar a perda de água em época de restrição hídrica, o que é considerado um mecanismo de tolerância à seca. O objetivo deste estudo foi avaliar genótipos de amendoim forrageiro, verificando o ângulo de inclinação da folha na época seca. |
Palavras-Chave: |
Amendoim forrageiro; Análisis estadístico; Ángulo de la hoja; Arachis pintoi cv Belmonte; Arachis pintoi cv BRS Mandobi; Cacauhetes forrajeros; Forage peanut; Leguminosas forrajeras; Método REML/BLUP; Toleracia a la sequía. |
Thesagro: |
Disposição de folhas; Genótipo; Leguminosa forrageira; Método estatístico; Resistência a seca. |
Thesaurus NAL: |
Drought tolerance; Forage legumes; Genotype; Leaf angle; Statistical analysis. |
Categoria do assunto: |
G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/174849/1/26561.pdf
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Marc: |
LEADER 01637nam a2200397 a 4500 001 2090112 005 2023-11-16 008 2018 bl uuuu u00u1 u #d 020 $a978-85-8236-078-1 100 1 $aSANTOS, C. F. dos 245 $aÂngulo de inclinação da folha de amendoim forrageiro na época seca.$h[electronic resource] 260 $aIn: SEMINÁRIO DE INICIAÇÃO CIENTÍFICA DA UFAC, 26., 2017, Rio Branco. Anais... Rio Branco: Ufac$c2018 300 $ap. 512. 520 $aA menor interceptação da radiação solar, oriunda do aumento do ângulo da folha em relação ao solo, tendendo à posição vertical, pode minimizar a perda de água em época de restrição hídrica, o que é considerado um mecanismo de tolerância à seca. O objetivo deste estudo foi avaliar genótipos de amendoim forrageiro, verificando o ângulo de inclinação da folha na época seca. 650 $aDrought tolerance 650 $aForage legumes 650 $aGenotype 650 $aLeaf angle 650 $aStatistical analysis 650 $aDisposição de folhas 650 $aGenótipo 650 $aLeguminosa forrageira 650 $aMétodo estatístico 650 $aResistência a seca 653 $aAmendoim forrageiro 653 $aAnálisis estadístico 653 $aÁngulo de la hoja 653 $aArachis pintoi cv Belmonte 653 $aArachis pintoi cv BRS Mandobi 653 $aCacauhetes forrajeros 653 $aForage peanut 653 $aLeguminosas forrajeras 653 $aMétodo REML/BLUP 653 $aToleracia a la sequía 700 1 $aMIQUELONI, D. P. 700 1 $aASSIS, G. M. L. de
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