Data/hora: 24/06/2024 11:47:35

Biblioteca(s): 	Embrapa Agroindústria de Alimentos.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 1	
Data corrente: 	23/08/2021	
Data da última atualização: 	09/05/2024	
Autoria: 	MELLO, F. V.; CUNHA, S. C.; FOGACA, F. H. dos S.; ALONSO, M. B.; TORRES, J. P. M.; FERNANDES, J. O.	
Afiliação: 	FLÁVIA V. MELLO, UNIVERSIDADE FEDRAL DO RIO DE JANEIRO; SARA C. CUNHA, UNIVERSIDADE DO PORTO; FABIOLA HELENA DOS SANTOS FOGACA, CTAA; MARIANA B. ALONSO, UNIVERSIDADE FEDERAL DO RIO DE JANEIRO; JOÃO PAULO M. TORRES, UNIVERSIDADE FEDERAL DO RIO DE JANEIRO; JOSÉ O. FERNANDES, UNIVERSIDADE DO PORTO.	
Título: 	Occurrence of pharmaceuticals in seafood from two Brazilian coastal areas: Implication for human risk assessment	
Ano de publicação: 	2022	
Fonte/Imprenta: 	Science of The Total Environment, v. 803, 149744, 2022.	
DOI: 	https://doi.org/10.1016/j.scitotenv.2021.149744	
Idioma: 	Inglês	
Conteúdo: 	Pharmaceuticals (PhACs) are considered emerging contaminants with potential accumulation in aquatic organisms. Thus, seafood consumption may cause long-term effects and health risk for consumers. In the present study, the occurrence of PhACs in seafood from two Brazilian coastal areas, Sepetiba Bay (n=43) and Parnaiba Delta River (n=48), was determined for the first time, and their potential risk for human health was assessed. An eco-friendly multi-analytes method was used, after being validated for the different types of matrices (mussels, fatty and lean fish). All compounds under study were detected at least in four seafood species, including chloramphenicol, an antibiotic prohibited in animal foods. Most PhACs had mean concentrations below limit of quantification. Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs), as well as simvastatin and carbamazepine were the main PhACs bioaccumulated in edible parts of seafood species from Brazil. The high trophic level carnivorous species, snook, was the most contaminated by NSAIDs, while bivalves were the seafood more contaminated by lipid regulators. The profile of contamination did not vary among different types of matrix, except in relation to carbamazepine and ketoprofen. These PhACs were more abundant in species from Sepetiba Bay, an area highly impacted by human influence. The estimated daily exposure for Brazilian population that consumes the studied species was up to 20.3 ng/kg bw/day via carib pointed-venus and 25.7 ng/kg bw/day via snooks, lower than acceptable daily intake. Thus, consumption of seafood species from Sepetiba Bay and Parnaiba Delta River seems to be safe to the population in what concerns the PhACs studied.	
Palavras-Chave: 	Drogas; Eco-friendly method; Emerging Pollutants; Método ecológico; Poluentes Emergentes.	
Thesagro: 	Mexilhão; Peixe; Poluente; Segurança Alimentar.	
Thesaurus Nal: 	Drugs; Fish; Food safety; Mussels.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Agroindústria de Alimentos (CTAA)	
Exemplares: 	CTAA - (15206-1) - UPC - AP - DD -  -  -  - DIS