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 | Acesso ao texto completo restrito à biblioteca da Embrapa Arroz e Feijão. Para informações adicionais entre em contato com cnpaf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Arroz e Feijão. |
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Data corrente: |
10/12/2019 |
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Data da última atualização: |
20/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GOMES, M. J. C.; LIMA, S. L. S.; ALVES, N. E. G.; ASSIS, A.; MOREIRA, M. E. C.; TOLEDO, R. C. L.; ROSA, C. O. B.; TEIXEIRA, O. R.; BASSINELLO, P. Z.; MEJÍA, E. G. de; MARTINO, H. S. D. |
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Afiliação: |
MARIANA J. C. GOMES, UNIVERSIDADE FEDERAL DE VIÇOSA; SÂMARA L. S. LIMA, UNIVERSIDADE FEDERAL DE VIÇOSA; NATÁLIA E. G. ALVES, UNIVERSIDADE FEDERAL DE VIÇOSA; ANDRESSA ASSIS, UNIVERSIDADE FEDERAL DE VIÇOSA; MARIA E. C. MOREIRA, UNIVERSIDADE FEDERAL DE VIÇOSA; RENATA C. L. TOLEDO, UNIVERSIDADE FEDERAL DE VIÇOSA; CARLA O. B. ROSA, UNIVERSIDADE FEDERAL DE VIÇOSA; OLÍVIA R. TEIXEIRA; PRISCILA ZACZUK BASSINELLO, CNPAF; ELVIRA G. DE MEJÍA, University of Illinois; HÉRCIA S. D. MARTINO, UNIVERSIDADE FEDERAL DE VIÇOSA. |
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Título: |
Common bean protein hydrolysate modulates lipid metabolism and prevents endothelial dysfunction in BALB/c mice fed an atherogenic diet. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Nutrition, Metabolism & Cardiovascular Diseases, v. 30, n. 1, p. 141-150, Jan. 2020. |
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ISSN: |
0939-4753 |
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DOI: |
10.1016/j.numecd.2019.07.020 |
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Idioma: |
Português |
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Conteúdo: |
Background and aims: Common beans (Phaseolus vulgaris L.) protein hydrolysate is a source of bioactive peptides with known health benefits. The aim of this study was to evaluate the effect of common bean protein hydrolysate on lipid metabolism and endothelial function in male adult BALB/c mice fed an atherogenic diet for nine weeks. Methods and results: Male adult mice were divided into three experimental groups (n = 12) and fed with normal control diet; atherogenic diet and atherogenic diet added with bean protein hydrolysate (700 mg/kg/day) for nine weeks. Food intake, weight gain, lipid profile, Atherogenic Index of Plasma, inflammation biomarkers and endothelial function were evaluated. APH group presented reduced feed intake, weight gain, lipid profile, tumor necrosis factor-a, angiotensin II (94% and 79%, respectively) and increased endothelial nitric oxide synthase (62%). Conclusions: Protein hydrolysate showed hypocholesterolemic activity preventing inflammation and dysfunction of vascular endothelium, in addition to decreasing oxidative stress, indicating an adjuvant effect on reducing atherogenic risk. |
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Thesagro: |
Feijão; Nutrição; Phaseolus Vulgaris; Proteína Hidrolisada; Saúde. |
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Thesaurus NAL: |
Beans; Nutrition; Protein hydrolysates. |
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Categoria do assunto: |
Q Alimentos e Nutrição Humana |
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Marc: |
LEADER 02225naa a2200361 a 4500
001 2116583
005 2020-04-20
008 2020 bl uuuu u00u1 u #d
022 $a0939-4753
024 7 $a10.1016/j.numecd.2019.07.020$2DOI
100 1 $aGOMES, M. J. C.
245 $aCommon bean protein hydrolysate modulates lipid metabolism and prevents endothelial dysfunction in BALB/c mice fed an atherogenic diet.$h[electronic resource]
260 $c2020
520 $aBackground and aims: Common beans (Phaseolus vulgaris L.) protein hydrolysate is a source of bioactive peptides with known health benefits. The aim of this study was to evaluate the effect of common bean protein hydrolysate on lipid metabolism and endothelial function in male adult BALB/c mice fed an atherogenic diet for nine weeks. Methods and results: Male adult mice were divided into three experimental groups (n = 12) and fed with normal control diet; atherogenic diet and atherogenic diet added with bean protein hydrolysate (700 mg/kg/day) for nine weeks. Food intake, weight gain, lipid profile, Atherogenic Index of Plasma, inflammation biomarkers and endothelial function were evaluated. APH group presented reduced feed intake, weight gain, lipid profile, tumor necrosis factor-a, angiotensin II (94% and 79%, respectively) and increased endothelial nitric oxide synthase (62%). Conclusions: Protein hydrolysate showed hypocholesterolemic activity preventing inflammation and dysfunction of vascular endothelium, in addition to decreasing oxidative stress, indicating an adjuvant effect on reducing atherogenic risk.
650 $aBeans
650 $aNutrition
650 $aProtein hydrolysates
650 $aFeijão
650 $aNutrição
650 $aPhaseolus Vulgaris
650 $aProteína Hidrolisada
650 $aSaúde
700 1 $aLIMA, S. L. S.
700 1 $aALVES, N. E. G.
700 1 $aASSIS, A.
700 1 $aMOREIRA, M. E. C.
700 1 $aTOLEDO, R. C. L.
700 1 $aROSA, C. O. B.
700 1 $aTEIXEIRA, O. R.
700 1 $aBASSINELLO, P. Z.
700 1 $aMEJÍA, E. G. de
700 1 $aMARTINO, H. S. D.
773 $tNutrition, Metabolism & Cardiovascular Diseases$gv. 30, n. 1, p. 141-150, Jan. 2020.
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