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| Registros recuperados : 4 | |
| 1. |  | CLEMENTE, Z.; SILVA, G. H. da; NUNES, M. C. S.; MARTINEZ, D. S. T.; MAURER-MORELLI, C. V.; THOMAZ, A. A.; CASTRO, V. L. S. S. de. Exploring the mechanisms of graphene oxide behavioral and morphological changes in zebrafish. Environmental Science and Pollution Research, v. 26, n. 29, p. 30508-30523, 2019.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 2. | | CLEMENTE, Z.; SILVA, G. H. da; MARTINEZ, D. S. T.; MAURER-MORELLI, C. V.; NUNES, M. C. S.; THOMAZ, A. A.; CASTRO, V. L. S. S. de. Exploring the mechanisms of graphene oxide toxicity to zebrafish embryo. Applied Research in Toxicology, v. 2, p. 56, 2017. Suppl. 1. Abstracts of International Symposium on Toxicity Assesment, 18., 2017, Limeira. Ref. ISTA18-705454.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 4. | | VALLIM, J. H.; CLEMENTE, Z.; CASTANHA, R. F.; PEREIRA, A. do E. S.; CAMPOS, E. V. R.; ASSALIN, M. R.; MAURER-MORELLI, C. V.; FRACETO, L. F.; CASTRO, V. L. S. S. de. Chitosan nanoparticles containing the insecticide dimethoate: a new approach in the reduction of harmful ecotoxicological effects. NanoImpact, v. 27, article 100408, 2022.| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 4 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
22/11/2022 |
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Data da última atualização: |
23/11/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
VALLIM, J. H.; CLEMENTE, Z.; CASTANHA, R. F.; PEREIRA, A. do E. S.; CAMPOS, E. V. R.; ASSALIN, M. R.; MAURER-MORELLI, C. V.; FRACETO, L. F.; CASTRO, V. L. S. S. de. |
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Afiliação: |
JOSE HENRIQUE VALLIM, CNPMA; ZAIRA CLEMENTE; RODRIGO FERNANDES CASTANHA, CNPMA; ANDERSON DO ESPÍRITO SANTO PEREIRA, UNIVERSIDADE ESTADUAL PAULISTA; ESTEFÂNIA VANGELIE RAMOS CAMPOS, UNIVERSIDADE ESTADUAL PAULISTA; MARCIA REGINA ASSALIN, CNPMA; CLÁUDIA VIANNA MAURER-MORELLI, UNIVERSIDADE ESTADUAL DE CAMPINAS; LEONARDO FERNANDES FRACETO, UNIVERSIDADE ESTADUAL PAULISTA; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA. |
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Título: |
Chitosan nanoparticles containing the insecticide dimethoate: a new approach in the reduction of harmful ecotoxicological effects. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
NanoImpact, v. 27, article 100408, 2022. |
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ISSN: |
2452-0748 |
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DOI: |
https://doi.org/10.1016/j.impact.2022.100408 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Organophosphate insecticides such as dimethoate (DMT) are widely used in agriculture. As a side effect, however, these insecticides contaminate bodies of water, resulting in damage to aquatic organisms. The development of nanopesticides may be an innovative alternative in the control of agricultural pests, increasing effectiveness and reducing their toxicological effects. Based upon this, the present study has investigated encapsulated DMT in alginate chitosan nanoparticles (nanoDMT) and evaluated its toxicological effects on non-target organisms. The nanoparticles were characterized by DLS, NTA and AFM, as well as being evaluated by the release profile. Nanoparticle toxicity was also evaluated in comparison with DMT, empty nanoparticles and DMT (NP + DMT), and commercial formulations (cDMT), in the embryos and larvae of Danio rerio (zebrafish) according to lethality, morphology, and behavior. The nanoparticle control (NP) showed hydrodynamic size values of 283 ± 4 nm, a PDI of 0.5 ± 0.05 and a zeta potential of -31 ± 0.4 mV. For nanoparticles containing dimethoate, the nanoparticles showed 301 ± 7 nm size values, a PDI of 0.45 ± 0.02, a zeta potential of -27.9 ± 0.2 mV, and an encapsulation of 75 ± 0.32%, with slow-release overtime (52% after 48 h). The AFM images showed that both types of nanoparticles showed spherical morphology. Major toxic effects on embryo larval development were observed in commercial dimethoate exposure followed by the technical pesticide, predominantly in the highest tested concentrations. With regard to the toxic effects of sodium alginate/chitosan, although there was an increase for LC50?96 h concerning the technical dimethoate, the behavior of the larvae was not affected. The data obtained demonstrate that nanoencapsulated dimethoate reduces the toxicity of insecticides on zebrafish larvae, suggesting that nanoencapsulation may be safer for non-target species, by eliminating collateral effects and thus promoting sustainable agriculture. MenosAbstract: Organophosphate insecticides such as dimethoate (DMT) are widely used in agriculture. As a side effect, however, these insecticides contaminate bodies of water, resulting in damage to aquatic organisms. The development of nanopesticides may be an innovative alternative in the control of agricultural pests, increasing effectiveness and reducing their toxicological effects. Based upon this, the present study has investigated encapsulated DMT in alginate chitosan nanoparticles (nanoDMT) and evaluated its toxicological effects on non-target organisms. The nanoparticles were characterized by DLS, NTA and AFM, as well as being evaluated by the release profile. Nanoparticle toxicity was also evaluated in comparison with DMT, empty nanoparticles and DMT (NP + DMT), and commercial formulations (cDMT), in the embryos and larvae of Danio rerio (zebrafish) according to lethality, morphology, and behavior. The nanoparticle control (NP) showed hydrodynamic size values of 283 ± 4 nm, a PDI of 0.5 ± 0.05 and a zeta potential of -31 ± 0.4 mV. For nanoparticles containing dimethoate, the nanoparticles showed 301 ± 7 nm size values, a PDI of 0.45 ± 0.02, a zeta potential of -27.9 ± 0.2 mV, and an encapsulation of 75 ± 0.32%, with slow-release overtime (52% after 48 h). The AFM images showed that both types of nanoparticles showed spherical morphology. Major toxic effects on embryo larval development were observed in commercial dimethoate exposure followed by the technical pesticide, ... Mostrar Tudo |
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Thesagro: |
Impacto Ambiental; Inseticida; Peixe de Água Doce; Toxidez. |
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Thesaurus NAL: |
Danio rerio; Dimethoate; Ecotoxicology; Encapsulation; Environmental impact; Nanocapsules; Toxicity. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
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100 1 $aVALLIM, J. H.
245 $aChitosan nanoparticles containing the insecticide dimethoate$ba new approach in the reduction of harmful ecotoxicological effects.$h[electronic resource]
260 $c2022
520 $aAbstract: Organophosphate insecticides such as dimethoate (DMT) are widely used in agriculture. As a side effect, however, these insecticides contaminate bodies of water, resulting in damage to aquatic organisms. The development of nanopesticides may be an innovative alternative in the control of agricultural pests, increasing effectiveness and reducing their toxicological effects. Based upon this, the present study has investigated encapsulated DMT in alginate chitosan nanoparticles (nanoDMT) and evaluated its toxicological effects on non-target organisms. The nanoparticles were characterized by DLS, NTA and AFM, as well as being evaluated by the release profile. Nanoparticle toxicity was also evaluated in comparison with DMT, empty nanoparticles and DMT (NP + DMT), and commercial formulations (cDMT), in the embryos and larvae of Danio rerio (zebrafish) according to lethality, morphology, and behavior. The nanoparticle control (NP) showed hydrodynamic size values of 283 ± 4 nm, a PDI of 0.5 ± 0.05 and a zeta potential of -31 ± 0.4 mV. For nanoparticles containing dimethoate, the nanoparticles showed 301 ± 7 nm size values, a PDI of 0.45 ± 0.02, a zeta potential of -27.9 ± 0.2 mV, and an encapsulation of 75 ± 0.32%, with slow-release overtime (52% after 48 h). The AFM images showed that both types of nanoparticles showed spherical morphology. Major toxic effects on embryo larval development were observed in commercial dimethoate exposure followed by the technical pesticide, predominantly in the highest tested concentrations. With regard to the toxic effects of sodium alginate/chitosan, although there was an increase for LC50?96 h concerning the technical dimethoate, the behavior of the larvae was not affected. The data obtained demonstrate that nanoencapsulated dimethoate reduces the toxicity of insecticides on zebrafish larvae, suggesting that nanoencapsulation may be safer for non-target species, by eliminating collateral effects and thus promoting sustainable agriculture.
650 $aDanio rerio
650 $aDimethoate
650 $aEcotoxicology
650 $aEncapsulation
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700 1 $aCASTRO, V. L. S. S. de
773 $tNanoImpact$gv. 27, article 100408, 2022.
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