Data/hora: 17/06/2024 01:04:56

Biblioteca(s): | Embrapa Gado de Leite.
Data corrente: | 31/07/2018
Data da última atualização: | 24/01/2023
Autoria: | VIEIRA, A. M.; BRASIEL, P. G. de A.; FERREIRA, M. S.; MATEUS, K.; FIGUEIREDO, M. S.; LISBOA, P. C.; MOURA, E. G. de; CORRÊA, J. O. do A.; LOPES, F. C. F.; SILVA, P. H. F. da; SABARENSE, C. M.; DUTRA, S. C. P. L.; AGUIAR, A. S. de.
Afiliação: | Adriana Moura Vieira, UFJF; Poliana Guiomar de Almeida Brasiel, UFJF; Maíra Schuchter Ferreira, UFJF; Kacia Mateus, UFJF; Mariana Sarto Figueiredo, UERJ; Patrícia Cristina Lisboa, UERJ; Egberto Gaspar de Moura, UERJ; José Otavio do Amaral Corrêa, UFJF; FERNANDO CESAR FERRAZ LOPES, CNPGL; Paulo Henrique Fonseca da Silva, UFJF; Céphora Maria Sabarense, UFJF; Sheila Cristina Potente Luquetti Dutra, UFJF; Aline Silva de Aguiar, UFJF.
Título: | Maternal soybean diet during lactation alters breast milk composition and programs the lipid profile in adult male rat offspring.
Ano de publicação: | 2018
Fonte/Imprenta: | Endocrine, v. 60, n. 2, p. 272-281, 2018.
Idioma: | Inglês
Conteúdo: | Abstract PURPOSE: To evaluate the effects of maternal dietary soybean during lactation on the milk composition, body composition, lipid profile and glucose homeostasis of dams and offspring at weaning (21 days) and adulthood (150 days). METHODS: Lactating rats were divided into: casein control (C): casein diet; soy (S): soybean diet; soy oil control (SOC): casein diet, but with fat content similar to the S group. RESULTS: At 21 days, S mothers showed lower estradiol, total cholesterol (TC), low-density lipoprotein cholesterol (LDL) and triglycerides (TG) in serum; and lower TC and TG in milk. The S offspring had lower body weight, body fat mass, TC, LDL, hyperleptinemia and hypertriglyceridemia. At 150 days, S offspring presented higher total mineral content and lower TC (v. SOC) and LDL (v. C and SOC), and hyperinsulinemia with lower glycemia v. SOC group, which had lower insulinemia with higher glycemia, TC and LDL. CONCLUSIONS: Maternal intake of soybeans in lactation changes the lipid content of breast milk and programmed offspring for phenotype of the lower metabolic risk, with lower serum TC and LDL, and seems to protect the progeny of alterations in glucose metabolism despite the higher lipid content. The difference in fat content of breast milk and the higher isoflavones content of soy diet are possible imprinting factors that could program the offspring.
Palavras-Chave: | Lipid profile; Programming; Soybean.
Thesaurus Nal: | Glucose; Lactation.
Categoria do assunto: | Q Alimentos e Nutrição Humana
Registro original: | Embrapa Gado de Leite (CNPGL)
Exemplares: | CNPGL - (24067-1) - UPC - AP - DD -  -  -  - DIS