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| Registros recuperados : 72 | |
| 61. |  | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; COLE, J. B.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; SILVA, M. V. G. B. Single nucleotide variants and indels identified from whole-genome resequencing of Gyr, Girolando, and Holstein cattle breeds. Journal of Animal Science, v. 95, p. 80-81, 2017. Suplemento 4, Resumo 164. Edição de Abstracts do ASAS-CSAS Annual Meeting and Trade Show, Baltimore, 2017. Na publicação: A. Zerlotini, M. V. G. B. da Silva.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 62. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Sequencing and de novo genome assembley of a Nelore (Bos indicus) bull. In: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. Abstracts... Jersey City: Scherago International, 2013. P0522.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 63. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Sequencing and de novo genome assembly of a nelore (Bos indicus) bull. In: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.], 2013. Não paginado. Pôster 0522.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Gado de Corte. |
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| 64. | | STAFUZZA, N. B.; ZERLOTINI, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; BUZANSKAS, M. E.; CHUD, T. C.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R. S.; COLE, J. B.; SILVA, M. V. G. B. Genetic variants with potencial loss of function in Gyr, Girolando, and Guzerat cattle breeds by resequencing. Journal of Animal Science, v. 95, n. 4, p. 81, 2017. Edição dos abstracts do of Breeding and Genetics Symposium, Baltimore, 2017.| Biblioteca(s): Embrapa Gado de Leite. |
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| 65. | | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; BUZANSKAS, M. E.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; COLE, J. B.; SILVA, M. V. G. B. Genetic variants with potential loss of function in Gyr, Girolando, and Guzerat cattle breeds by resequencing. Journal of Animal Science, v. 95, p. 81, 2017. Suplemento 4, Resumo 165. Edição de Abstracts do ASAS-CSAS Annual Meeting and Trade Show, Baltimore, 2017. Na publicação: A. Zerlotini, M. V. G. B. da Silva.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 66. | | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; BUZANSKAS, M. E.; CHUD, T. C.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R. S.; COLE, J. B.; SILVA, M. V. G. B. Genetiv variants with potencial loss of function in Gyr, Girolando, and Guzerat cattle breeds by resequencing. Journal of Animal Science, v. 95, n. suppl. 4, p. 81, 2017. Abstract of Breeding and Genetics Symposium, Baltimore, 2017.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 67. | | PANDOLFI, J. R. C.; SILVA, V. S.; KRAMER, B.; LOBO, F. P.; ZANELLI, C. F.; ARAUJO, F. R.; CALICH, V. L. G.; PEIXOTO, J. de O.; CANTAO, M. E.; MORES, N.; LOYOLA, W.; GRINGS, V. H.; COLDEBELLA, A.; SLUSZZ, T.; BORDIN, L. C.; LAZZAROTTI, M.; LOPES, L. dos S.; IBELLI, A. M. G.; AMARAL, A. L. do; TESSMANN, A. L. Prospection and production of recombinant antigens for the diagnosis of animal tuberculosis. In: SIMPÓSIO EMBRAPA LabEx EUA DE SANIDADE ANIMAL, 2., 2012, Brasília. Anais... Brasília: Embrapa Estudos e Capacitação, 2012. p. 50-51. Projeto/Plano de Ação: 11.11.11.111.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 68. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. De novo assembly of a Nelore (Bos indicus) bull genome based on short read sequences. In: PLANT & ANIMAL GENOME CONFERENCE, 22., 2014, San Diego, CA. [Abstracts]. San Diego: [s.n.], 2014. Não paginado. P554.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 69. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. De novo assembly of a Nelore (Bos indicus) bull genome based on short read sequences. In: PLANT & ANIMAL GENOME CONFERENCE, 22., 2014, San Diego, CA. [Abstracts...]. San Diego: [s.n.], 2014. Não paginado. P554.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 70. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Next generation sequencing and de novo assembly of a Nelore (Bos indicus) bull genome. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 64., 2013, Nantes. Abstracts... Session 25, Poster 34| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 71. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Next generation sequencing and de novo assembly of a Nelore (Bos indicus) bull genome. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 64., 2013, Nantes. Abstracts... Session 25, Poster 34| Biblioteca(s): Embrapa Gado de Corte. |
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| 72. | | RUIZ, J. C.; D'AFONSECA, V.; SILVA, A.; ALI, A.; PINTO, A. C.; SANTOS, A. R.; ROCHA, A. A. M. C.; LOPES, D. O.; DORELLA, F. A.; PACHECO, L. G. C.; COSTA, M. P.; TURK, M. Z.; SEYFFERT, N.; MORAES, P. M. R. O.; SOARES, S. C.; ALMEIDA, S. S.; CASTRO, T. L. P.; ABREU, V. A. C.; TROST, E.; BAUMBACH, J.; TAUCH, A.; SCHNEIDER, M. P. C.; McCULLOCH, J.; CERDEIRA, L. T.; RAMOS, R. T. J.; ZERLOTINI, A.; DOMINITINI, A.; RESENDE, D. M.; COSER, E. M.; OLIVEIRA, L. M.; PEDROSA, A. L.; VIEIRA, C. U.; GUIMARAES, C. T.; BARTHOLOMEU, D. C.; OLIVEIRA, D. M.; SANTOS, F. R.; RABELO, E. M.; LOBO, F. P.; FRANCO, G. R.; COSTA, A. F.; CASTRO, I. M.; DIAS, S. R. C.; FERRO, J. A.; ORTEGA, J. M.; PAIVA, L. V.; ALMEIDA, J. F.; GOULART, L. R.; FERRO, M. I. T.; CARNEIRO, N. P.; FALCÃO, P. R. K.; GRYNBERG, P.; TEIXEIRA, S. M. R.; BROMMONSCHENKEL, S.; OLIVEIRA, S. C.; MEYER, R.; MOORE, R. J.; MIYOSHI, A.; OLIVEIRA, G. C.; AZEVEDO, V. Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. Plos One, San Francisco, v. 6, n. 4, p. 1-16, 2011.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Milho e Sorgo. |
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| Registros recuperados : 72 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
19/05/2017 |
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Data da última atualização: |
30/12/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; COLE, J. B.; SILVA, M. V. G. B. |
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Afiliação: |
NEDENIA BONVINO STAFUZZA, FCAV/Unesp; ADHEMAR ZERLOTINI NETO, CNPTIA; FRANCISCO PEREIRA LOBO, CNPTIA; MICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; TATIANE CRISTINA SELEGUIM CHUD, FCAV/Unesp; ALEXANDRE RODRIGUES CAETANO, Cenargen; DANÍSIO PRADO MUNARI, FCAV/Unesp; DORIAN J. GARRICK, Iowa State University; MARCO ANTONIO MACHADO, CNPGL; MARTA FONSECA MARTINS, CNPGL; MARIA RAQUEL CARVALHO, UFMG; JOHN BRUCE COLE, Agricultural Research Service; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
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Título: |
Single nucleotide variants and InDels identified from whole-genome re-sequencing of Guzerat, Gyr, Girolando and Holstein cattle breeds. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Plos One, v. 12, n. 3, p. 1-15, 2017. |
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DOI: |
https://doi.org/10.1371/journal.pone.0173954 |
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Idioma: |
Inglês |
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Notas: |
Artigo e0173954. Na publicação: Adhemar Zerlotini, Marcos Vinicius Gualberto Barbosa da Silva. |
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Conteúdo: |
Whole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated molecular mechanisms that impact economically important traits for Gyr, Girolando, Guzerat and Holstein breeding programs. MenosWhole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated... Mostrar Tudo |
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Palavras-Chave: |
Genetic variants; Genomic markers; Important traits; Molecular mechanisms; Polimorfismo de nucleotídeo único; Potential genomic markers; Raças bovinas; Single nucleotide variations. |
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Thesagro: |
Gado; Variação genética. |
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Thesaurus NAL: |
Cattle breeds; Genome; Single nucleotide polymorphism; Sires. |
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Categoria do assunto: |
--
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/171980/1/AP-Single-nucleotide-Stafuzza-etal.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/161515/1/Cnpgl-2017-PlosOne-Stafuzza-Single.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/180929/1/journal.pone.0173954.pdf
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Marc: |
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024 7 $ahttps://doi.org/10.1371/journal.pone.0173954$2DOI
100 1 $aSTAFUZZA, N. B.
245 $aSingle nucleotide variants and InDels identified from whole-genome re-sequencing of Guzerat, Gyr, Girolando and Holstein cattle breeds.$h[electronic resource]
260 $c2017
500 $aArtigo e0173954. Na publicação: Adhemar Zerlotini, Marcos Vinicius Gualberto Barbosa da Silva.
520 $aWhole-genome re-sequencing, alignment and annotation analyses were undertaken for 12 sires representing four important cattle breeds in Brazil: Guzerat (multi-purpose), Gyr, Girolando and Holstein (dairy production). A total of approximately 4.3 billion reads from an Illumina HiSeq 2000 sequencer generated for each animal 10.7 to 16.4-fold genome coverage. A total of 27,441,279 single nucleotide variations (SNVs) and 3,828,041 insertions/deletions (InDels) were detected in the samples, of which 2,557,670 SNVs and 883,219 InDels were novel. The submission of these genetic variants to the dbSNP database significantly increased the number of known variants, particularly for the indicine genome. The concordance rate between genotypes obtained using the Bovine HD BeadChip array and the same variants identified by sequencing was about 99.05%. The annotation of variants identified numerous non-synonymous SNVs and frameshift InDels which could affect phenotypic variation. Functional enrichment analysis was performed and revealed that variants in the olfactory transduction pathway was over represented in all four cattle breeds, while the ECM-receptor interaction pathway was over represented in Girolando and Guzerat breeds, the ABC transporters pathway was over represented only in Holstein breed, and the metabolic pathways was over represented only in Gyr breed. The genetic variants discovered here provide a rich resource to help identify potential genomic markers and their associated molecular mechanisms that impact economically important traits for Gyr, Girolando, Guzerat and Holstein breeding programs.
650 $aCattle breeds
650 $aGenome
650 $aSingle nucleotide polymorphism
650 $aSires
650 $aGado
650 $aVariação genética
653 $aGenetic variants
653 $aGenomic markers
653 $aImportant traits
653 $aMolecular mechanisms
653 $aPolimorfismo de nucleotídeo único
653 $aPotential genomic markers
653 $aRaças bovinas
653 $aSingle nucleotide variations
700 1 $aZERLOTINI NETO, A.
700 1 $aLOBO, F. P.
700 1 $aYAMAGISHI, M. E. B.
700 1 $aCHUD, T. C. S.
700 1 $aCAETANO, A. R.
700 1 $aMUNARI, D. P.
700 1 $aGARRICK, D. J.
700 1 $aMACHADO, M. A.
700 1 $aMARTINS, M. F.
700 1 $aCARVALHO, M. R.
700 1 $aCOLE, J. B.
700 1 $aSILVA, M. V. G. B.
773 $tPlos One$gv. 12, n. 3, p. 1-15, 2017.
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Embrapa Agricultura Digital (CNPTIA) |
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