Data/hora: 23/06/2024 01:41:38

Biblioteca(s): 	Embrapa Milho e Sorgo.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 1	
Data corrente: 	08/11/2022	
Data da última atualização: 	08/11/2022	
Autoria: 	VEREDIANO, T. A.; AGARWAL, N.; MARTINO, H. S. D.; KOLBA, N.; GRANCIERI, M.; PAES, M. C. D.; TAKO, E.	
Afiliação: 	THAISA AGRIZZI VEREDIANO, Universidade Federal de Viçosa; NIKITA AGARWAL, Cornell University; HÉRCIA STAMPINI DUARTE MARTINO, Universidade Federal de Viçosa; NIKOLAI KOLBA, Cornell University; MARIANA GRANCIERI, Universidade Federal de Viçosa; MARIA CRISTINA DIAS PAES, CNPMS; ELAD TAKO, Cornell University.	
Título: 	Effect of black corn anthocyanin-rich extract (Zea mays L.) on cecal microbial populations in vivo (Gallus gallus).	
Ano de publicação: 	2022	
Fonte/Imprenta: 	Nutrients, v. 14, n. 21, 4679, 2022.	
DOI: 	https://doi.org/10.3390/nu14214679	
Idioma: 	Inglês	
Conteúdo: 	Black corn has been attracting attention to investigate its biological properties due to its anthocyanin composition, mainly cyanidin-3-glucoside. Our study evaluated the effects of black corn extract (BCE) on intestinal morphology, gene expression, and the cecal microbiome. The BCE intra-amniotic administration was evaluated by an animal model in Gallus gallus. The eggs (n = 8 per group) were divided into: (1) no injection; (2) 18 M&#8486; H2O; (3) 5% black corn extract (BCE); and (4) 0.38% cyanidin-3-glucoside (C3G). A total of 1 mL of each component was injected intra-amniotic on day 17 of incubation. On day 21, the animals were euthanized after hatching, and the duodenum and cecum content were collected. The cecal microbiome changes were attributed to BCE administration, increasing the population of Bifidobacterium and Clostridium, and decreasing E. coli. The BCE did not change the gene expression of intestinal inflammation and functionality. The BCE administration maintained the villi height, Paneth cell number, and goblet cell diameter (in the villi and crypt), similar to the H2O injection but smaller than the C3G. Moreover, a positive correlation was observed between Bifidobacterium, Clostridium, E. coli, and villi GC diameter. The BCE promoted positive changes in the cecum microbiome and maintained intestinal morphology and functionality	
Palavras-Chave: 	Barreira intestinal; Célula caliciforme; Cianidina; Intestinal barrier; Milho preto; Phenolic components.	
Thesagro: 	Antocianina; Milho; População Microbiana.	
Thesaurus Nal: 	Cyanidin; Goblet cells.	
Categoria do assunto: 	Q Alimentos e Nutrição Humana	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1148119/1/Effect-of-black-corn-anthocyanin-rich-extract.pdf	
Registro original: 	Embrapa Milho e Sorgo (CNPMS)	
Exemplares: 	CNPMS - (29909-1) - UPC - AP - DD -  -  -  - DIS