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| 5. |  | PINHEIRO, R. S. B.; JORGE, A. M.; SOUZA, H. B. A.; BOIAGO, M. M. Coloração da gordura e qualidade da carne de ovelhas de descarte abatidas em distintos estágios fisiológicos. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, v. 62, n. 2, p. 468-474, fev., 2010.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 8. | | PINHEIRO, R. S. B.; JORGE, A. M.; SOUZA, H. B. A. de. Características da carcaça e dos não-componentes da carcaça de ovelhas de descarte abatidas em diferentes estágios fisiológicos. Revista Brasileira de Zootecnia, Viçosa, MG, v. 38, n. 7, p. 1322-1328, jul., 2009.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 11. | | JORGE, A. G. L. S.; ALENCAR, N. F. de; CANDIDO, H. M.; BASSINELLO, P. Z.; COLOMBARI FILHO, J. M. Avaliação de linhagens elite de pericarpo preto para o desenvolvimento de novas cultivares de arroz especial. In: SEMINÁRIO JOVENS TALENTOS, 11., 2017, Santo Antônio de Goiás. Coletânea dos resumos apresentados. Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2017. p. 44. (Embrapa Arroz e Feijão. Documentos, 316).| Biblioteca(s): Embrapa Arroz e Feijão. |
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| 13. | | VILELA, S. F. G.; BARBOSA, J. O.; ROSSONI, R. D.; SANTOS, J. D.; PRATA, M. C. de A.; ANBINDER, A. L.; JORGE, A. O. C.; JUNQUEIRA, J. C. Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella. Virulence, v. 6, n. 1, p. 29-39, 2015.| Biblioteca(s): Embrapa Gado de Leite. |
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| 14. | | ROSSONI, R. D.; BARBOSA, J. O.; VILELA, S. F. G.; SANTOS, J. D.; PRATA, M. C. de A.; JORGE, A. O. C.; JUNQUEIRA, J. C. Interaction between Candida albicans and krusei: in vivo study using galleria mellonella and immunosuppressed mice as a model hosts. In: CONGRESS OF EUROPEAN MICROBIOLOGISTS, 5., 2013, Leipzig, Germany. Abstracts... Leipzig: [s.n.], 2013.| Biblioteca(s): Embrapa Gado de Leite. |
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| 15. | | HONSHO, C. S.; JORGE, A. T.; OLIVEIRA, L. T.; PAULINO-JUNIOR, D.; MATTOS JUNIOR, E.; NISHIMURA, L. T.; DIAS, W. O. Intraocular pressure and Schirmer tear test values in maned wolf (Chrysocyon brachyurus). Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 9, p. 919-923, set. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 16. | | CANDIDO, H. M.; JORGE, A. G. L. S.; ALENCAR, N. F. de; MAGALHAES JUNIOR, A. M. de; BASSINELLO, P. Z.; COLOMBARI FILHO, J. M. Desempenho agronômico de linhagens de arroz irrigado em ensaios de VCU para tipos especiais. In: SEMINÁRIO JOVENS TALENTOS, 11., 2017, Santo Antônio de Goiás. Coletânea dos resumos apresentados. Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2017. p. 54. (Embrapa Arroz e Feijão. Documentos, 316).| Biblioteca(s): Embrapa Arroz e Feijão. |
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| 17. | | CÃNDIDO, H. M.; JORGE, A. G. L. S.; ALENCAR, N. F. de; MAGALHÃES JUNIOR, A. M. de; BASSINELLO, P. Z.; VANIER, N. L.; COLOMBARI FILHO, J. M. Desempenho agronômico de linhagens de arroz irrigado em ensaios de VCU para tipos especiais. In: CONGRESSO BRASILEIRO DE ARROZ IRRIGADO, 10., 2017, Gramado. Intensificação sustentável: anais. Gramado: Sosbai, 2017.| Biblioteca(s): Embrapa Arroz e Feijão. |
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| 18. | | RESENDE, F. D. de; QEUIROZ, A. C. de; FONTES, C. A. de A.; RODRIGUEZ, R. R.; FREITAS, J. A. de; SOARES, J. E.; JORGE, A. M. Fibra em detergente neutro versus fibra em detergente acido na formulacao de dietas para ruminantes. Revista da Sociedade Brasleira de Zootecnia, v.24, n.3, p.342-350, 1995.| Biblioteca(s): Embrapa Caprinos e Ovinos. |
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| 19. | | LOPES, E. R.; MORGADO, T. O.; MEIRELES, Y. S.; JORGE, A. A.; ZAGO, A. A. Q.; CORRÊA, S. H. R.; PAZ, R. C. R. da; NÉSPOLI, P. B. Ultrassonografia abdominal de tamanduás-bandeira (Myrmecophaga tridactyla Linnaeus, 1758) mantidos em cativeiro. Pesquisa Veterinária Brasileira, Brasília, DF, v. 35, n. 11, p. 919-924, nov. 2015.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 20. | | ALENCAR, N. F. de; CANDIDO, H. M.; JORGE, A. G. L. S.; RANGEL, P. H. N.; ABREU, A. G. de; BASSINELLO, P. Z.; COLOMBARI FILHO, J. M. Caracterização morfoagronômica de recursos genéticos de arroz aromático tipo basmati para utilização no melhoramento genético. In: SEMINÁRIO JOVENS TALENTOS, 11., 2017, Santo Antônio de Goiás. Coletânea dos resumos apresentados. Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2017. p. 22. (Embrapa Arroz e Feijão. Documentos, 316).| Biblioteca(s): Embrapa Arroz e Feijão. |
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| Registros recuperados : 32 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
04/10/2011 |
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Data da última atualização: |
23/09/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SALLES, H. O.; VASCONCELOS, I. M.; SANTOS, L. F. L.; OLIVEIRA, H. D.; COSTA, P. P. C.; NASCIMENTO, N. R. F.; SANTOS, C. F.; SOUSA, D. F.; JORGE, A. R. C.; MENEZES, D. B.; MONTEIRO, H. S. A.; GONDIM, D. M. F.; OLIVEIRA, J. T. A. |
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Afiliação: |
HEVILA OLIVEIRA SALLES FIGUEIREDO, CNPC; Universidade Federal do Ceará (UFC), Fortaleza, CE.; Universidade Estadual do Ceará (UECe) - Fortaleza, CE.; UECe; UECe; UECe; UECe; UFC, Fortaleza, CE.; UFC; UFC; UFC; UFC; UFC. |
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Título: |
Towards a better understanding of Ipomoea asarifolia toxicity: evidence of the involvement of a leaf lectin. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Toxicon, v. 58, p. 502-508, 2011. |
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DOI: |
10.1016/j.toxicon.2011.08.011 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Natural intoxication of livestock by ingestion of Ipomoea asarifolia leaves has been reported to occur widely in Brazil. Previous studies carried out by our research group provided strong evidence that a lectin could be involved with the toxic properties of I. asarifolia.To reinforce this hypothesis, a lectin-enriched fraction (LEF) was isolated from I. asarifolia leaves and its toxic effects were assessed. Leaves of I. asarifolia were excised from plants growing widely in the ?eld, mechanically wounded and maintained in a chamber at 25 3 C for 72 h in the dark, under near 100% relative humidity. The leaf proteins were extracted, ammonium sulfate precipitated, chromatographed on DEAE-cellulose and Phenyl-Sepharose to produce LEF that under SDS?PAGE showed a molecular mass of 44.0 kDa and after N-terminal amino acid analysis a primary sequence composed of AGYTPVLDIGAEVLAAGEPY. The in vivo toxicity of LEF assessed by intraorbital injection in mice showed induced severe uncoordinated movements without death. LEF reduced the muscular contraction in a dose depend way and at 29.8 mg/mL (CE50) it produces 50% inhibition of contraction, suggesting that LEF blunts autonomic neurotransmission. Isolated rat kidneys were perfused with LEF and no effects on the perfusion pressure or renal vascular resistance were observed, but urinary ?ow and glomerular ?ltration rate increased. Moreover, the percentage of tubular transport of Naþ,Kþ and Cl decreased. Histological examination of the kidneys perfused with LEF exhibited little alterations. These toxic effects observed above were concomitant with the increase of LEF hemag-glutination activity, which strongly suggest that one of the toxic principles of I. asarifolia is a lectin present in its leaves. MenosAbstract: Natural intoxication of livestock by ingestion of Ipomoea asarifolia leaves has been reported to occur widely in Brazil. Previous studies carried out by our research group provided strong evidence that a lectin could be involved with the toxic properties of I. asarifolia.To reinforce this hypothesis, a lectin-enriched fraction (LEF) was isolated from I. asarifolia leaves and its toxic effects were assessed. Leaves of I. asarifolia were excised from plants growing widely in the ?eld, mechanically wounded and maintained in a chamber at 25 3 C for 72 h in the dark, under near 100% relative humidity. The leaf proteins were extracted, ammonium sulfate precipitated, chromatographed on DEAE-cellulose and Phenyl-Sepharose to produce LEF that under SDS?PAGE showed a molecular mass of 44.0 kDa and after N-terminal amino acid analysis a primary sequence composed of AGYTPVLDIGAEVLAAGEPY. The in vivo toxicity of LEF assessed by intraorbital injection in mice showed induced severe uncoordinated movements without death. LEF reduced the muscular contraction in a dose depend way and at 29.8 mg/mL (CE50) it produces 50% inhibition of contraction, suggesting that LEF blunts autonomic neurotransmission. Isolated rat kidneys were perfused with LEF and no effects on the perfusion pressure or renal vascular resistance were observed, but urinary ?ow and glomerular ?ltration rate increased. Moreover, the percentage of tubular transport of Naþ,Kþ and Cl decreased. Histological examination o... Mostrar Tudo |
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Palavras-Chave: |
Ipomoea asarifolia; Lectin; Sulato de amônia. |
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Thesagro: |
Erva daninha; Lectina; Planta tóxica; Salsa; Toxidez. |
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Thesaurus NAL: |
toxicity. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02855naa a2200385 a 4500
001 1902176
005 2019-09-23
008 2011 bl uuuu u00u1 u #d
024 7 $a10.1016/j.toxicon.2011.08.011$2DOI
100 1 $aSALLES, H. O.
245 $aTowards a better understanding of Ipomoea asarifolia toxicity$bevidence of the involvement of a leaf lectin.$h[electronic resource]
260 $c2011
520 $aAbstract: Natural intoxication of livestock by ingestion of Ipomoea asarifolia leaves has been reported to occur widely in Brazil. Previous studies carried out by our research group provided strong evidence that a lectin could be involved with the toxic properties of I. asarifolia.To reinforce this hypothesis, a lectin-enriched fraction (LEF) was isolated from I. asarifolia leaves and its toxic effects were assessed. Leaves of I. asarifolia were excised from plants growing widely in the ?eld, mechanically wounded and maintained in a chamber at 25 3 C for 72 h in the dark, under near 100% relative humidity. The leaf proteins were extracted, ammonium sulfate precipitated, chromatographed on DEAE-cellulose and Phenyl-Sepharose to produce LEF that under SDS?PAGE showed a molecular mass of 44.0 kDa and after N-terminal amino acid analysis a primary sequence composed of AGYTPVLDIGAEVLAAGEPY. The in vivo toxicity of LEF assessed by intraorbital injection in mice showed induced severe uncoordinated movements without death. LEF reduced the muscular contraction in a dose depend way and at 29.8 mg/mL (CE50) it produces 50% inhibition of contraction, suggesting that LEF blunts autonomic neurotransmission. Isolated rat kidneys were perfused with LEF and no effects on the perfusion pressure or renal vascular resistance were observed, but urinary ?ow and glomerular ?ltration rate increased. Moreover, the percentage of tubular transport of Naþ,Kþ and Cl decreased. Histological examination of the kidneys perfused with LEF exhibited little alterations. These toxic effects observed above were concomitant with the increase of LEF hemag-glutination activity, which strongly suggest that one of the toxic principles of I. asarifolia is a lectin present in its leaves.
650 $atoxicity
650 $aErva daninha
650 $aLectina
650 $aPlanta tóxica
650 $aSalsa
650 $aToxidez
653 $aIpomoea asarifolia
653 $aLectin
653 $aSulato de amônia
700 1 $aVASCONCELOS, I. M.
700 1 $aSANTOS, L. F. L.
700 1 $aOLIVEIRA, H. D.
700 1 $aCOSTA, P. P. C.
700 1 $aNASCIMENTO, N. R. F.
700 1 $aSANTOS, C. F.
700 1 $aSOUSA, D. F.
700 1 $aJORGE, A. R. C.
700 1 $aMENEZES, D. B.
700 1 $aMONTEIRO, H. S. A.
700 1 $aGONDIM, D. M. F.
700 1 $aOLIVEIRA, J. T. A.
773 $tToxicon$gv. 58, p. 502-508, 2011.
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