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Registro Completo |
Biblioteca(s): |
Embrapa Soja. |
Data corrente: |
25/10/2012 |
Data da última atualização: |
26/07/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
HAGEN, M. K.; LUDKE, A.; ARAUJO, A. S.; MENDES, R. H.; FERNANDES, T. G.; MANDARINO, J. M. G.; LLESUY, S.; JONG, E. V. de; BELLÓ-KLEIN, A. |
Afiliação: |
MARTINE KIENZLE HAGEN, UFRGS; ANA LUDKE, University of Manitoba; ALEX SANDER ARAUJO, UFRGS; ROBERTA HACK MENDES, UFRGS; TÂNIA GATELLI FERNANDES, UFRGS; JOSE MARCOS GONTIJO MANDARINO, CNPSO; SUSANA LLESUY, Universidade de Buenos Aires; ERNA VOGT DE JONG, UFRGS; ADRIANE BELLÓ-KLEIN, UFRGS. |
Título: |
Antioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model. |
Ano de publicação: |
2012 |
Fonte/Imprenta: |
Canadian Journal of Physiology and Pharmacology, Ottawa, v. 90, n. 8, p. 1095-1103, 2012. |
DOI: |
10.1139/y2012-028 |
Idioma: |
Inglês |
Conteúdo: |
This study analyzed and compared the content of isoflavones in 2 soy products, the effectiveness of isoflavones as antioxidants, in vitro, and demonstrated the antioxidant effect of a soy diet in rats with myocardial infarction (MI). Isoflavone content was analyzed in soybean hypocotyl (SH) and isolated soy protein (ISP). The quality (TAR) and quantity (TRAP) of antioxidants present in the samples was quantified. The amount of daidzin was higher in SH (9 times) and genistein in ISP (5 times). SH presented a 3-fold increase in TAR, while both products exhibited same TRAP. The rats were fed an ISP diet for 9 weeks. Animals were distributed among 6 treatment groups: (i) Sham Casein; (ii) Infarct Casein < 25%; (iii) Infarct Casein > 25%; (iv) Sham Soy; (v) Infarct Soy < 25%; and (vi) Infarct Soy > 25%. MI was induced 5 weeks after the commencement of the diets. Lipid peroxidation (LPO), antioxidant enzyme activity, and levels of nitrites/nitrates were determined in blood. Rats receiving the ISP diet demonstrated increased activity of antioxidant enzyme activity and nitrite/nitrate content. In addition, the increase in LPO seen in rats subjected to MI was significantly mitigated when the ISP diet was given. These findings suggest a nutritional approach of using a soy-based diet for the prevention of oxidative-stress-related diseases such as heart failure. |
Thesagro: |
Antioxidante; Enzima; Lipidio; Peroxidase; Proteína; Soja. |
Thesaurus Nal: |
Lipid peroxidation; Nitric oxide; Plant proteins; Soybeans. |
Categoria do assunto: |
W Química e Física |
Marc: |
LEADER 02405naa a2200349 a 4500 001 1938034 005 2017-07-26 008 2012 bl uuuu u00u1 u #d 024 7 $a10.1139/y2012-028$2DOI 100 1 $aHAGEN, M. K. 245 $aAntioxidant characterization of soy derived products in vitro and the effect of a soy diet on peripheral markers of oxidative stress in a heart disease model. 260 $c2012 520 $aThis study analyzed and compared the content of isoflavones in 2 soy products, the effectiveness of isoflavones as antioxidants, in vitro, and demonstrated the antioxidant effect of a soy diet in rats with myocardial infarction (MI). Isoflavone content was analyzed in soybean hypocotyl (SH) and isolated soy protein (ISP). The quality (TAR) and quantity (TRAP) of antioxidants present in the samples was quantified. The amount of daidzin was higher in SH (9 times) and genistein in ISP (5 times). SH presented a 3-fold increase in TAR, while both products exhibited same TRAP. The rats were fed an ISP diet for 9 weeks. Animals were distributed among 6 treatment groups: (i) Sham Casein; (ii) Infarct Casein < 25%; (iii) Infarct Casein > 25%; (iv) Sham Soy; (v) Infarct Soy < 25%; and (vi) Infarct Soy > 25%. MI was induced 5 weeks after the commencement of the diets. Lipid peroxidation (LPO), antioxidant enzyme activity, and levels of nitrites/nitrates were determined in blood. Rats receiving the ISP diet demonstrated increased activity of antioxidant enzyme activity and nitrite/nitrate content. In addition, the increase in LPO seen in rats subjected to MI was significantly mitigated when the ISP diet was given. These findings suggest a nutritional approach of using a soy-based diet for the prevention of oxidative-stress-related diseases such as heart failure. 650 $aLipid peroxidation 650 $aNitric oxide 650 $aPlant proteins 650 $aSoybeans 650 $aAntioxidante 650 $aEnzima 650 $aLipidio 650 $aPeroxidase 650 $aProteína 650 $aSoja 700 1 $aLUDKE, A. 700 1 $aARAUJO, A. S. 700 1 $aMENDES, R. H. 700 1 $aFERNANDES, T. G. 700 1 $aMANDARINO, J. M. G. 700 1 $aLLESUY, S. 700 1 $aJONG, E. V. de 700 1 $aBELLÓ-KLEIN, A. 773 $tCanadian Journal of Physiology and Pharmacology, Ottawa$gv. 90, n. 8, p. 1095-1103, 2012.
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Embrapa Soja (CNPSO) |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
05/08/2015 |
Data da última atualização: |
31/08/2015 |
Tipo da produção científica: |
Resumo em Anais de Congresso |
Autoria: |
MORAES, L. S. R.; JARDIM, I. C. S. F.; QUEIROZ, S. C. do N. de; FERRACINI, V. L.; GOMES, M. A. F. |
Afiliação: |
L. S. R. MORAES, IQ/Unicamp; I. C. S. F. JARDIM, IQ/Unicamp; SONIA CLAUDIA DO N DE QUEIROZ, CNPMA; VERA LUCIA FERRACINI, CNPMA; MARCO ANTONIO FERREIRA GOMES, CNPMA. |
Título: |
Desenvolvimento de metodologia para a determinação de herbicidas em águas das nascentes do rio Araguaia, GO/MT. |
Ano de publicação: |
2005 |
Fonte/Imprenta: |
In: ENCONTRO NACIONAL DE QUÍMICA ANALÍTICA, 13., CONGRESSO IBERO-AMERICANO DE QUÍMICA ANALÍTICA, 1., 2005, Niterói/RJ. A química analítica e o desenvolvimento sustentável. Niterói/RJ: UFF, 2005. |
Idioma: |
Português |
Palavras-Chave: |
Rio Araguaia. |
Thesagro: |
Água; Herbicida. |
Categoria do assunto: |
W Química e Física |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/127506/1/2005RA-055.pdf
|
Marc: |
LEADER 00746nam a2200181 a 4500 001 2021411 005 2015-08-31 008 2005 bl uuuu u00u1 u #d 100 1 $aMORAES, L. S. R. 245 $aDesenvolvimento de metodologia para a determinação de herbicidas em águas das nascentes do rio Araguaia, GO/MT.$h[electronic resource] 260 $aIn: ENCONTRO NACIONAL DE QUÍMICA ANALÍTICA, 13., CONGRESSO IBERO-AMERICANO DE QUÍMICA ANALÍTICA, 1., 2005, Niterói/RJ. A química analítica e o desenvolvimento sustentável. Niterói/RJ: UFF$c2005 650 $aÁgua 650 $aHerbicida 653 $aRio Araguaia 700 1 $aJARDIM, I. C. S. F. 700 1 $aQUEIROZ, S. C. do N. de 700 1 $aFERRACINI, V. L. 700 1 $aGOMES, M. A. F.
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