| |
|
|
| Registros recuperados : 213 | |
| Registros recuperados : 213 | |
|
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Agricultura Digital. |
|
Data corrente: |
07/01/2010 |
|
Data da última atualização: |
15/01/2020 |
|
Tipo da produção científica: |
Resumo em Anais de Congresso |
|
Autoria: |
HIGA, R. H.; TOZZI, C. L. |
|
Afiliação: |
ROBERTO HIROSHI HIGA, CNPTIA; CLÉSIO LUIS TOZZI, FEEC/UNICAMP. |
|
Título: |
Prediction of binding hot spot residues by using structural and evolutionary parameters. |
|
Ano de publicação: |
2008 |
|
Fonte/Imprenta: |
In: INTERNATIONAL CONFERENCE OF BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 4., 2008, Salvador. Proceedings... Salvador: AB³C, 2008. |
|
Páginas: |
Não paginado. |
|
Idioma: |
Inglês |
|
Notas: |
X-meeting 2008. |
|
Conteúdo: |
In this work, we present a method for predicting hot spot residues by using a set of structural and evolutionary parameters. Unlike previous studies, we use a set of parameters which do not depend on the structure of the protein in complex, so that the predictor can also be used when the interface region is unknown. Despite the fact that no information concerning proteins in complex is used for prediction, the application of the method to a compiled dataset described in the literature achieved a performance of 60.4 percent, as measured by F-Measure, corresponding to a recall of 78.1 percent and a precision of 49.5 percent. This result is higher than those reported by previous studies using the same data set. |
|
Palavras-Chave: |
Estrutura proteica; Hot spot residues; Hot spots; Hot spots prediction; Interações proteína-proteína. |
|
Thesaurus NAL: |
Protein structure. |
|
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
|
Marc: |
LEADER 01492nam a2200217 a 4500
001 1579862
005 2020-01-15
008 2008 bl uuuu u00u1 u #d
100 1 $aHIGA, R. H.
245 $aPrediction of binding hot spot residues by using structural and evolutionary parameters.$h[electronic resource]
260 $aIn: INTERNATIONAL CONFERENCE OF BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 4., 2008, Salvador. Proceedings... Salvador: AB³C$c2008
300 $aNão paginado.
500 $aX-meeting 2008.
520 $aIn this work, we present a method for predicting hot spot residues by using a set of structural and evolutionary parameters. Unlike previous studies, we use a set of parameters which do not depend on the structure of the protein in complex, so that the predictor can also be used when the interface region is unknown. Despite the fact that no information concerning proteins in complex is used for prediction, the application of the method to a compiled dataset described in the literature achieved a performance of 60.4 percent, as measured by F-Measure, corresponding to a recall of 78.1 percent and a precision of 49.5 percent. This result is higher than those reported by previous studies using the same data set.
650 $aProtein structure
653 $aEstrutura proteica
653 $aHot spot residues
653 $aHot spots
653 $aHot spots prediction
653 $aInterações proteína-proteína
700 1 $aTOZZI, C. L.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
