Data/hora: 20/06/2024 11:48:14

Biblioteca(s): 	Embrapa Agroindústria de Alimentos.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 1	
Data corrente: 	27/07/2015	
Data da última atualização: 	12/02/2016	
Autoria: 	SILVA, C. M.; ROSA, L. O. L.; STEPHAN, M. P.; BRIGIDA, A. I. S.; CABRAL, L. M. C.; SILVA, G. O. DA; GUARIDO, K. L.; GOMES, D. M.; SILVA-SANTOS, J. E. DA.	
Afiliação: 	CAROLINE MELLINGER SILVA, CTAA; LUISA O. L. ROSA, UFRJ; MARILIA PENTEADO STEPHAN, CTAA; ANA IRAIDY SANTA BRIGIDA, CTAA; LOURDES MARIA CORREA CABRAL, CTAA; GABRIEL O. DA SILVA, UFSC; KARLA L. GUARIDO, UFSC; DANILO MACÊDO GOMES, UFSC; JOSÉ EDUARDO DA SILVA-SANTOS, UFSC.	
Título: 	Dual function peptides from pepsin hydrolysates of whey protein isolate.	
Ano de publicação: 	2015	
Fonte/Imprenta: 	International Dairy Journal, v. 48, p. 73-79, sep., 2015.	
ISSN: 	0958-6946	
Idioma: 	Inglês	
Conteúdo: 	The aim of this study was to investigate the effect of pepsin hydrolysates of whey protein isolate (WPI) on vascular relaxation and emulsifying capacity. WPI was subjected to pepsin hydrolysis for 5 h. The chromatographic profiles of the samples showed the formation of a wide variety of peptides. Addition of WPI hydrolysates in phenylephrine-contracted rat aortic rings induced a similar concentrationdependent relaxation in both endothelium-intact and endothelium-denuded preparations. In endothelium-denuded vessels the maximum relaxation induced by WPI fractions increased along the time, reaching over 70% after 3 h-hydrolysis on. In addition, the vascular relaxation was not associated with an inhibition of the angiotensin-converting enzyme or activation of Kþ channels. Hydrolysed fractions were further evaluated for the emulsifying capacity (EC) and all tested fractions were able to keep an EC over 60%. These results reinforce the potential of WPI pepsin-hydrolysates as an option in the search for dual function peptides from whey proteins.	
Palavras-Chave: 	Pepsin hydrolysates; Protein isolate; WPI.	
Categoria do assunto: 	Q Alimentos e Nutrição Humana	
Registro original: 	Embrapa Agroindústria de Alimentos (CTAA)	
Exemplares: 	CTAA - (12834-1) - UPC - AP - DD -  -  -  - DIS