|
|
| Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Corte. Para informações adicionais entre em contato com cnpgc.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Corte. |
Data corrente: |
17/07/2018 |
Data da última atualização: |
27/09/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
ANDREOTTI, R.; GIACHETTO, P. F.; CUNHA, R. C. |
Afiliação: |
RENATO ANDREOTTI E SILVA, CNPGC; POLIANA FERNANDA GIACHETTO, CNPTIA; RODRIGO CASQUERO CUNHA, Bolsista PNPD/Capes. |
Título: |
Advances in tick vaccinology in Brazil: from gene expression to immunoprotection. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
Frontiers in Bioscience - Scholar, v. 10, n. 1, p. 127-142, Jan. 2018 |
Idioma: |
Inglês |
Conteúdo: |
Rhipicephalus (Boophilus) microplus has substantial economic impact on the cattle breeding industry and, chemical control and tick resistance development are the major concern. There is a worldwide search for new options, and control using vaccines has been the main focus nowadays. Studies performed in Brazil found that Bm86-based immunization of bovines reduced the infestation of R. (B.) microplus of vaccinated bovines by 45% to 60%. Native Boophilus microplus tripsin inhibitors (BmTIs) with trypsin-, kallikrein-, and elastase-inhibiting activities have been used as immunogens in bovines reaching 72.8.% of efficacy. The reverse vaccinology approach has also been used for antigen search using transcriptome analysis to identify and characterize potential antigens. Study has generated more than 600 million sequences using RNA-seq of larvae, nymphs, salivary glands, intestines, and ovaries of the tick R. (B) microplus. Based on the set of transcripts obtained using this strategy, a total of 20,326 protein sequences have been identified. A pipeline analysis built in house identified the protein sequences that were most likely to be immunogenic based on the overall structural characteristic analysis. |
Thesagro: |
Vacina. |
Thesaurus Nal: |
Gene expression; Rhipicephalus microplus; Transcriptome; Vaccines. |
Categoria do assunto: |
-- X Pesquisa, Tecnologia e Engenharia |
Marc: |
LEADER 01823naa a2200205 a 4500 001 2093371 005 2018-09-27 008 2018 bl uuuu u00u1 u #d 100 1 $aANDREOTTI, R. 245 $aAdvances in tick vaccinology in Brazil$bfrom gene expression to immunoprotection.$h[electronic resource] 260 $c2018 520 $aRhipicephalus (Boophilus) microplus has substantial economic impact on the cattle breeding industry and, chemical control and tick resistance development are the major concern. There is a worldwide search for new options, and control using vaccines has been the main focus nowadays. Studies performed in Brazil found that Bm86-based immunization of bovines reduced the infestation of R. (B.) microplus of vaccinated bovines by 45% to 60%. Native Boophilus microplus tripsin inhibitors (BmTIs) with trypsin-, kallikrein-, and elastase-inhibiting activities have been used as immunogens in bovines reaching 72.8.% of efficacy. The reverse vaccinology approach has also been used for antigen search using transcriptome analysis to identify and characterize potential antigens. Study has generated more than 600 million sequences using RNA-seq of larvae, nymphs, salivary glands, intestines, and ovaries of the tick R. (B) microplus. Based on the set of transcripts obtained using this strategy, a total of 20,326 protein sequences have been identified. A pipeline analysis built in house identified the protein sequences that were most likely to be immunogenic based on the overall structural characteristic analysis. 650 $aGene expression 650 $aRhipicephalus microplus 650 $aTranscriptome 650 $aVaccines 650 $aVacina 700 1 $aGIACHETTO, P. F. 700 1 $aCUNHA, R. C. 773 $tFrontiers in Bioscience - Scholar$gv. 10, n. 1, p. 127-142, Jan. 2018
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Gado de Corte (CNPGC) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registros recuperados : 6 | |
1. | | VIVENZA, P. A. D.; PANCOTI, C. G.; BORGES, A. L. C. C.; LOPES, F. C. F.; CAMPOS, M. M.; FONSECA, M. P. DA; LAGE, H. F. Avaliação da digestibilidade e consumo da materia organica e proteina bruta de dietas a base de cana de açucar tratada com oxido de calcio em diferentes tempos de hidrolise, na alimentação de novilhas mestiças holandes x zebu. In: Congresso Brasileiro de Zootecnia, 21., 2011, Maceió. Anais...Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
| |
4. | | LOPES, F. C. F.; AMARAL, G. M. P. de M.; LAGE, H. F.; RODRIGUES, J. A. S.; SILVA, J. S. da; FONSECA, M. P. da. Produção de metano por novilhos suplementados com aditivos. In: SEMANA DE INICIAÇÃO CIENTÍFICA DA UFMG, 21., 2012, Belo Horizonte, MG. [Resumos]... Belo Horizonte: Universidade Federal de Minas Gerais, 2012.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
| |
5. | | PANCOTI, C. G.; BORGES, A. L. DA C. C.; LOPES, F. C. F.; SILVA, R. R. E; CAMPOS, M. M.; SILVA, J. S.; LAGE, H. F.; FONSECA, M. P. DA. Comportamento ingestivo de novilhas recebendo dietas contendo cana de açucar tratada com oxido de calcio em diferentes tempos de hidrolise. In: Congresso Brasileiro de Zootecnia, 21., 2011, Maceió. Anais...Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
| |
6. | | FONSECA, M. P. da; BORGES, A. L. da C. C.; SILVA, R. R. e; LAGE, H. F.; FERREIRA, A. L.; LOPES, F. C. F.; PANCOTI, C. G.; RODRIGUES, J. A. S. Intake, apparent digestibility, and methane emission in bulls receiving a feed supplement of monensin, virginiamycin, or a combination. Animal Production Science, v. 56, n. 7, p. 1041-1045, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite; Embrapa Milho e Sorgo. |
| |
Registros recuperados : 6 | |
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|