|
|
![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Instrumentação. |
Data corrente: |
19/10/2021 |
Data da última atualização: |
09/06/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MERCANTE, L. A.; ANDRE, R. S.; FACURE, M. H. M.; FUGIKAWA-SANTOS, L.; CORREA, D. S. |
Afiliação: |
DANIEL SOUZA CORREA, CNPDIA. |
Título: |
Design of a bioelectronic tongue for glucose monitoring using zinc oxide nanofibers and graphene derivatives. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Sensors and Actuators Reports, v. 3, 100050, 2021. |
ISSN: |
2666-0539 |
DOI: |
https://doi.org/10.1016/j.snr.2021.100050 |
Idioma: |
Inglês |
Conteúdo: |
Monitoring glucose levels is critical for diabetes management and might be a key step in the development of individualized treatment strategies. In this scenario, tracking salivary glucose has been recognized as a promising strategy due to its merits of ease sampling and non-invasive nature. In this paper, we report on the development of an electrical impedance-based biosensor array to distinguish glucose at different concentrations in saliva. The enzymatic biosensors were made of gold interdigitated electrodes coated with pristine electrospun zinc oxide nanofibers (NFZ) and NFZ combined with graphene-based nanomaterials (i.e., reduced graphene oxide - rGO and graphene quantum dots - GQDs), on which a layer of glucose oxidase (GOx) enzyme was adsorbed. Electrical impedance measurements indicate that the NFZ-GQDs@GOx and NFZ-rGO@GOx platforms presented good linear relationship with glucose concentration in the range of 0.1 to 6 mM. The highest sensitivity was reached for NFZ-rGO@GOx with a detection limit (LOD) of 14 μM, while the LOD was 32 μM for NFZ-GQDs@GOx. Both biosensors were also capable of detecting glucose in artificial saliva using aliquots of 10 μL, with recovery between 87.3 and 106.8%. Furthermore, the three sensing units (NFZ@GOx, NFZ-rGO@GOx and NFZ-GQDs@GOx) were employed to build a bioelectronic tongue. Using Principal Component Analysis (PCA) technique to project the electrical impedance data of all sensing units allowed the discrimination of the different glucose concentrations and interferents. This study reveals the applicability of the developed bioelectronic tongue as noninvasive glucose sensors, which approach could also be pottentially adapted to detect other disease biomarkers present in saliva MenosMonitoring glucose levels is critical for diabetes management and might be a key step in the development of individualized treatment strategies. In this scenario, tracking salivary glucose has been recognized as a promising strategy due to its merits of ease sampling and non-invasive nature. In this paper, we report on the development of an electrical impedance-based biosensor array to distinguish glucose at different concentrations in saliva. The enzymatic biosensors were made of gold interdigitated electrodes coated with pristine electrospun zinc oxide nanofibers (NFZ) and NFZ combined with graphene-based nanomaterials (i.e., reduced graphene oxide - rGO and graphene quantum dots - GQDs), on which a layer of glucose oxidase (GOx) enzyme was adsorbed. Electrical impedance measurements indicate that the NFZ-GQDs@GOx and NFZ-rGO@GOx platforms presented good linear relationship with glucose concentration in the range of 0.1 to 6 mM. The highest sensitivity was reached for NFZ-rGO@GOx with a detection limit (LOD) of 14 μM, while the LOD was 32 μM for NFZ-GQDs@GOx. Both biosensors were also capable of detecting glucose in artificial saliva using aliquots of 10 μL, with recovery between 87.3 and 106.8%. Furthermore, the three sensing units (NFZ@GOx, NFZ-rGO@GOx and NFZ-GQDs@GOx) were employed to build a bioelectronic tongue. Using Principal Component Analysis (PCA) technique to project the electrical impedance data of all sensing units allowed the discrimination of the different ... Mostrar Tudo |
Palavras-Chave: |
Electrospinning; Electrospinning Electrospun nanofibers; Reduced graphene oxide. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02503naa a2200229 a 4500 001 2135416 005 2022-06-09 008 2021 bl uuuu u00u1 u #d 022 $a2666-0539 024 7 $ahttps://doi.org/10.1016/j.snr.2021.100050$2DOI 100 1 $aMERCANTE, L. A. 245 $aDesign of a bioelectronic tongue for glucose monitoring using zinc oxide nanofibers and graphene derivatives.$h[electronic resource] 260 $c2021 520 $aMonitoring glucose levels is critical for diabetes management and might be a key step in the development of individualized treatment strategies. In this scenario, tracking salivary glucose has been recognized as a promising strategy due to its merits of ease sampling and non-invasive nature. In this paper, we report on the development of an electrical impedance-based biosensor array to distinguish glucose at different concentrations in saliva. The enzymatic biosensors were made of gold interdigitated electrodes coated with pristine electrospun zinc oxide nanofibers (NFZ) and NFZ combined with graphene-based nanomaterials (i.e., reduced graphene oxide - rGO and graphene quantum dots - GQDs), on which a layer of glucose oxidase (GOx) enzyme was adsorbed. Electrical impedance measurements indicate that the NFZ-GQDs@GOx and NFZ-rGO@GOx platforms presented good linear relationship with glucose concentration in the range of 0.1 to 6 mM. The highest sensitivity was reached for NFZ-rGO@GOx with a detection limit (LOD) of 14 μM, while the LOD was 32 μM for NFZ-GQDs@GOx. Both biosensors were also capable of detecting glucose in artificial saliva using aliquots of 10 μL, with recovery between 87.3 and 106.8%. Furthermore, the three sensing units (NFZ@GOx, NFZ-rGO@GOx and NFZ-GQDs@GOx) were employed to build a bioelectronic tongue. Using Principal Component Analysis (PCA) technique to project the electrical impedance data of all sensing units allowed the discrimination of the different glucose concentrations and interferents. This study reveals the applicability of the developed bioelectronic tongue as noninvasive glucose sensors, which approach could also be pottentially adapted to detect other disease biomarkers present in saliva 653 $aElectrospinning 653 $aElectrospinning Electrospun nanofibers 653 $aReduced graphene oxide 700 1 $aANDRE, R. S. 700 1 $aFACURE, M. H. M. 700 1 $aFUGIKAWA-SANTOS, L. 700 1 $aCORREA, D. S. 773 $tSensors and Actuators Reports$gv. 3, 100050, 2021.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Instrumentação (CNPDIA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registro Completo
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
22/03/2012 |
Data da última atualização: |
05/04/2019 |
Tipo da produção científica: |
Comunicado Técnico/Recomendações Técnicas |
Autoria: |
LAGUNA, L. E.; EGITO, A. S. do; BENEVIDES, S. D.; SANTOS, K. M. O. dos; LIMA, A. R. |
Afiliação: |
LUIS EDUARDO LAGUNA, CNPC; ANTONIO SILVIO DO EGITO, CNPC; SELENE DAIHA BENEVIDES, CNPC; KARINA MARIA OLBRICH DOS SANTOS, CNPC; ADRIANO RODRIGUES LIMA, CNPC. |
Título: |
Queijo de cabra maturado adicionado de pasta de pimentão. |
Ano de publicação: |
2011 |
Fonte/Imprenta: |
Sobral: Embrapa Caprinos e Ovinos, 2011. |
Páginas: |
5 f. |
Série: |
(Embrapa Caprinos e Ovinos. Comunicado Técnico, 125). |
Idioma: |
Português |
Notas: |
Prática / Processo Agropecuário |
Palavras-Chave: |
Pasta de pimentão; Queijo de cabra. |
Thesagro: |
Caprino; Capsicum Annuum; Pimentão; Planta Para Condimento; Produto derivado do leite; Tecnologia de alimento. |
Thesaurus NAL: |
Goat cheese. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/58378/1/COT-125.pdf
|
Marc: |
LEADER 00875nam a2200289 a 4500 001 1919896 005 2019-04-05 008 2011 bl uuuu u0uu1 u #d 100 1 $aLAGUNA, L. E. 245 $aQueijo de cabra maturado adicionado de pasta de pimentão.$h[electronic resource] 260 $aSobral: Embrapa Caprinos e Ovinos$c2011 300 $a5 f. 490 $a(Embrapa Caprinos e Ovinos. Comunicado Técnico, 125). 500 $aPrática / Processo Agropecuário 650 $aGoat cheese 650 $aCaprino 650 $aCapsicum Annuum 650 $aPimentão 650 $aPlanta Para Condimento 650 $aProduto derivado do leite 650 $aTecnologia de alimento 653 $aPasta de pimentão 653 $aQueijo de cabra 700 1 $aEGITO, A. S. do 700 1 $aBENEVIDES, S. D. 700 1 $aSANTOS, K. M. O. dos 700 1 $aLIMA, A. R.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
Expressão de busca inválida. Verifique!!! |
|
|