| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Arroz e Feijão. |
|
Data corrente: |
06/11/2017 |
|
Data da última atualização: |
06/11/2017 |
|
Tipo da produção científica: |
Artigo em Anais de Congresso |
|
Autoria: |
VIANELLO, R. P. |
|
Afiliação: |
ROSANA PEREIRA VIANELLO, CNPAF. |
|
Título: |
Advances in common bean genome-wide analysis and impacts for the breeding programs. |
|
Ano de publicação: |
2017 |
|
Fonte/Imprenta: |
In: CONGRESSO NACIONAL DE PESQUISA DE FEIJÃO, 12., 2017, Piracicaba. Produtividade e sustentabilidade da cultura do feijão: do campo para a mesa: resumos. Piracicaba: CENA: IAC, 2017. |
|
Páginas: |
p. 285-286. |
|
Idioma: |
Inglês |
|
Notas: |
CONAFE. Palestra. |
|
Conteúdo: |
Conservation and knowledge of common bean genetic resources for sustainable management and proper utilization are of great importance to increase genetic gain in breeding programs. The Brazilian common bean core collection (CONFE) represents the genetic diversity of a large collection and presents a great potential to be widely explored to improve utilization of germplams for association analysis of agronomic traits and genome selection. In the last years, SNP markers have been increasingly developed based on the analysis of the accessions from CONFE, and applied for genetic analysis, investigation of the genetic structure along the domestication sites and breeding programs, as well as the identification of genomic regions related to traits of agronomic interest through association analysis and genomic selection. |
|
Palavras-Chave: |
Association panel; Melhoramento genético; Molecular breeding. |
|
Thesagro: |
Feijão; Phaseolus vulgaris. |
|
Thesaurus Nal: |
Beans; Genetic variation. |
|
Categoria do assunto: |
S Ciências Biológicas |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/166097/1/CNPAF-2017-conafep285.pdf
|
|
Marc: |
LEADER 01604nam a2200217 a 4500
001 2078882
005 2017-11-06
008 2017 bl uuuu u00u1 u #d
100 1 $aVIANELLO, R. P.
245 $aAdvances in common bean genome-wide analysis and impacts for the breeding programs.$h[electronic resource]
260 $aIn: CONGRESSO NACIONAL DE PESQUISA DE FEIJÃO, 12., 2017, Piracicaba. Produtividade e sustentabilidade da cultura do feijão: do campo para a mesa: resumos. Piracicaba: CENA: IAC$c2017
300 $ap. 285-286.
500 $aCONAFE. Palestra.
520 $aConservation and knowledge of common bean genetic resources for sustainable management and proper utilization are of great importance to increase genetic gain in breeding programs. The Brazilian common bean core collection (CONFE) represents the genetic diversity of a large collection and presents a great potential to be widely explored to improve utilization of germplams for association analysis of agronomic traits and genome selection. In the last years, SNP markers have been increasingly developed based on the analysis of the accessions from CONFE, and applied for genetic analysis, investigation of the genetic structure along the domestication sites and breeding programs, as well as the identification of genomic regions related to traits of agronomic interest through association analysis and genomic selection.
650 $aBeans
650 $aGenetic variation
650 $aFeijão
650 $aPhaseolus vulgaris
653 $aAssociation panel
653 $aMelhoramento genético
653 $aMolecular breeding
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Arroz e Feijão (CNPAF) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Agricultura Digital. |
|
Data corrente: |
14/02/2013 |
|
Data da última atualização: |
08/01/2020 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 2 |
|
Autoria: |
BITAR, M.; DRUMMOND, M. G.; COSTA, M. G. S.; LOBO, F. P.; CALZAVARA-SILVA, C. E.; BISCH, P. M.; MACHADO, C. R.; MACEDO, A. M.; PIERCE, R. J.; FRANCO, G. R. |
|
Afiliação: |
MAINÁ BITAR, UFRJ, UFMG; MARCELA GONÇALVES DRUMMOND, UFMG, Univ. Lille Nord de France; MAURICIO GARCIA SOUZA COSTA, UFRJ; FRANCISCO PEREIRA LOBO, CNPTIA; CARLOS EDUARDO CALZAVARA-SILVA, Fiocruz; PAULO MASCARELLO BISCH, UFRJ; CARLOS RENATO MACHADO, UFMG; ANDRÉA MARA MACEDO, UFMG; RAYMOND J. PIERCE, Univ. Lille Nord de France; GLÓRIA REGINA FRANCO, UFMG. |
|
Título: |
Modeling the zing finger protein SmZF1 from Schistosoma mansoni: Insights into DNA binding and gene regulation. |
|
Ano de publicação: |
2013 |
|
Fonte/Imprenta: |
Journal of Molecular Graphics and Modelling, New York, v. 39, p. 29-38, 2013. |
|
Idioma: |
Inglês |
|
Conteúdo: |
Zinc finger proteins are widely found in eukaryotes, representing an important class of DNA-binding proteins frequently involved in transcriptional regulation. Zinc finger motifs are composed by two antiparallel b-strands and one a-helix, stabilized by a zinc ion coordinated by conserved histidine and cysteine residues. In Schistosoma mansoni, these regulatory proteins are known to modulate morphological and physiological changes, having crucial roles in parasite development. A previously described C2H2 zinc finger protein, SmZF1, was shown to be present in cell nuclei of different life stages of S. mansoni and to activate gene transcription in a heterologous system. A high-quality SmZF1 tridimensional structure was generated using comparative modeling. Molecular dynamics simulations of the obtained structure revealed stability of the zinc fingers motifs and high flexibility on the terminals, comparable to the profile observed on the template X-ray structure based on thermal b-factors. Based on the protein tridimensional features and amino acid composition, we were able to characterize four C2 H2 zinc finger motifs, the first involved in protein?protein interactions while the three others involved in DNA binding. We defined a consensus DNA binding sequence using three distinct algorithms and further carried out docking calculations, which revealed the interaction of fingers 2?4 with the predicted DNA. A search for S. mansoni genes presenting putative SmZF1 binding sites revealed 415 genes hypothetically under SmZF1 control. Using an automatic annotation and GO assignment approach, we found that the majority of those genes code for proteins involved in developmental processes. Taken together, these results present a consistent base to the structural and functional characterization of SmZF1. MenosZinc finger proteins are widely found in eukaryotes, representing an important class of DNA-binding proteins frequently involved in transcriptional regulation. Zinc finger motifs are composed by two antiparallel b-strands and one a-helix, stabilized by a zinc ion coordinated by conserved histidine and cysteine residues. In Schistosoma mansoni, these regulatory proteins are known to modulate morphological and physiological changes, having crucial roles in parasite development. A previously described C2H2 zinc finger protein, SmZF1, was shown to be present in cell nuclei of different life stages of S. mansoni and to activate gene transcription in a heterologous system. A high-quality SmZF1 tridimensional structure was generated using comparative modeling. Molecular dynamics simulations of the obtained structure revealed stability of the zinc fingers motifs and high flexibility on the terminals, comparable to the profile observed on the template X-ray structure based on thermal b-factors. Based on the protein tridimensional features and amino acid composition, we were able to characterize four C2 H2 zinc finger motifs, the first involved in protein?protein interactions while the three others involved in DNA binding. We defined a consensus DNA binding sequence using three distinct algorithms and further carried out docking calculations, which revealed the interaction of fingers 2?4 with the predicted DNA. A search for S. mansoni genes presenting putative SmZF1 binding sites reve... Mostrar Tudo |
|
Palavras-Chave: |
Ligação de DNA; Regulação gênica. |
|
Thesagro: |
Schistosoma Mansoni. |
|
Thesaurus NAL: |
DNA-binding proteins; Gene expression regulation; Zinc finger motif. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02751naa a2200301 a 4500
001 1949183
005 2020-01-08
008 2013 bl uuuu u00u1 u #d
100 1 $aBITAR, M.
245 $aModeling the zing finger protein SmZF1 from Schistosoma mansoni$bInsights into DNA binding and gene regulation.$h[electronic resource]
260 $c2013
520 $aZinc finger proteins are widely found in eukaryotes, representing an important class of DNA-binding proteins frequently involved in transcriptional regulation. Zinc finger motifs are composed by two antiparallel b-strands and one a-helix, stabilized by a zinc ion coordinated by conserved histidine and cysteine residues. In Schistosoma mansoni, these regulatory proteins are known to modulate morphological and physiological changes, having crucial roles in parasite development. A previously described C2H2 zinc finger protein, SmZF1, was shown to be present in cell nuclei of different life stages of S. mansoni and to activate gene transcription in a heterologous system. A high-quality SmZF1 tridimensional structure was generated using comparative modeling. Molecular dynamics simulations of the obtained structure revealed stability of the zinc fingers motifs and high flexibility on the terminals, comparable to the profile observed on the template X-ray structure based on thermal b-factors. Based on the protein tridimensional features and amino acid composition, we were able to characterize four C2 H2 zinc finger motifs, the first involved in protein?protein interactions while the three others involved in DNA binding. We defined a consensus DNA binding sequence using three distinct algorithms and further carried out docking calculations, which revealed the interaction of fingers 2?4 with the predicted DNA. A search for S. mansoni genes presenting putative SmZF1 binding sites revealed 415 genes hypothetically under SmZF1 control. Using an automatic annotation and GO assignment approach, we found that the majority of those genes code for proteins involved in developmental processes. Taken together, these results present a consistent base to the structural and functional characterization of SmZF1.
650 $aDNA-binding proteins
650 $aGene expression regulation
650 $aZinc finger motif
650 $aSchistosoma Mansoni
653 $aLigação de DNA
653 $aRegulação gênica
700 1 $aDRUMMOND, M. G.
700 1 $aCOSTA, M. G. S.
700 1 $aLOBO, F. P.
700 1 $aCALZAVARA-SILVA, C. E.
700 1 $aBISCH, P. M.
700 1 $aMACHADO, C. R.
700 1 $aMACEDO, A. M.
700 1 $aPIERCE, R. J.
700 1 $aFRANCO, G. R.
773 $tJournal of Molecular Graphics and Modelling, New York$gv. 39, p. 29-38, 2013.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
