Data/hora: 23/09/2024 12:21:54

Biblioteca(s): 	Embrapa Pecuária Sudeste.	
Data corrente: 	27/10/2014	
Data da última atualização: 	20/03/2023	
Autoria: 	DINIZ, W. J. da S.; TIZIOTO, P.; MOKRY, F. B.; MUDADU, M. de A.; REGITANO, L. C. de A.	
Afiliação: 	WELLISON JARLES DA SILVA DINIZ, UFSCar/SÃO CARLOS, SP; POLYANA CRISTINE TIZIOTO, UFSCar/SÃO CARLOS, SP; FABIANA BARICHELLO MORKRY, UFSCar/SÃO CARLOS, SP; MAURICIO DE ALVARENGA MUDADU, CPPSE; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.	
Título: 	Refinamento de uma região de QTL associada à maciez de carne em bovinos da raça Nelore.	
Ano de publicação: 	2014	
Fonte/Imprenta: 	Ciência e Tecnologia, v. 6, p. 39-43, 2014.	
Idioma: 	Português	
Conteúdo: 	Meat tenderness is the key factor for consumer acceptance. It is known that this trait is at least moderately heritable, so the understanding of its genetic architecture can contribute to the development of quantitative and molecular criteria for beef cattle selection. The aim of this work was to construct haplotype blocks in a QTL region previously described in a genome wide association study in order to reduce its size of 1 Mb and associate them with meat tenderness to identify potential positional candidate genes. For this, genotypes of 374 Nellore animals represented in Illumina BeadChip in the BTA 23 at 24 Mb were used. In this QTL region, where 570 SNPs are located, 149 blocks with size ranging from 0.8 to 23 Kb were formed. Among the 149 haplotypes built, 40 blocks was found as associated with the target trait (p<0.05). In this region, nine genes that are related to physiological processes, such as calcium homeostasis, post-transcriptional processing of proteins and genome replication were identified. This strategy allowed the reduction of QTL size and the identification of putative functional genes, however further studies are needed to determine the role of these genes in meat tenderness.	
Palavras-Chave: 	Shear force; SNP chip.	
Thesaurus Nal: 	meat quality.	
Categoria do assunto: 	G Melhoramento Genético	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/110632/1/PROCI-2014.00082.pdf	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CPPSE - (22654-1) - UPC - AP - DD - PROCI-2014.00082 - DIN - 2014.00082 - DIS